| Item | Information |
|---|---|
| CAS RN | 147-14-8 |
| Chemical Name | Phthalocyanine Blue |
| Substance ID | H28-A-043, C-094A |
| Classification year (FY) | FY2016 |
| Ministry who conducted the classification | Ministry of Health, Labour and Welfare (MHLW)/Ministry of the Environment (MOE) |
| New/Revised | New |
| Classification result in other fiscal year | |
| Download of Excel format | Excel file |
| Item | Information |
|---|---|
| Guidance used for the classification (External link) | GHS Classification Guidance for the Japanese Government (FY2013 revised edition (Ver. 1.1)) |
| UN GHS document (External link) | UN GHS document |
| Definitions/Abbreviations (Excel file) | Definitions/Abbreviations |
| Model Label by MHLW (External link) | MHLW Website (in Japanese Only) |
| Model SDS by MHLW (External link) | MHLW Website (in Japanese Only) |
| OECD/eChemPortal (External link) | eChemPortal |
| Hazard class | Classification |
Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable |
- |
- | - | There are no chemical groups associated with explosive properties present in the molecule. |
| 2 | Flammable gases (including chemically unstable gases) | Not applicable |
- |
- | - | Solid (GHS definition). |
| 3 | Aerosols | Not applicable |
- |
- | - | Not aerosol products. |
| 4 | Oxidizing gases | Not applicable |
- |
- | - | Solid (GHS definition). |
| 5 | Gases under pressure | Not applicable |
- |
- | - | Solid (GHS definition). |
| 6 | Flammable liquids | Not applicable |
- |
- | - | Solid (GHS definition). |
| 7 | Flammable solids | Classification not possible |
- |
- | - | No data available. Besides, it is written that it is poorly flammable (GESTIS (Access on July 2016)). |
| 8 | Self-reactive substances and mixtures | Not applicable |
- |
- | - | There are no chemical groups present in the molecule associated with explosive or self-reactive properties. |
| 9 | Pyrophoric liquids | Not applicable |
- |
- | - | Solid (GHS definition). |
| 10 | Pyrophoric solids | Classification not possible |
- |
- | - | No data available. Besides, it is written that it is poorly flammable (GESTIS (Access on July 2016)). |
| 11 | Self-heating substances and mixtures | Classification not possible |
- |
- | - | No data available. Besides, it is written that it is poorly flammable (GESTIS (Access on July 2016)). |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified |
- |
- | - | It is estimated that it does not react vigorously with water due to the observation result of being insoluble in water (ICSC(J) (2006)). |
| 13 | Oxidizing liquids | Not applicable |
- |
- | - | Solid (GHS definition). |
| 14 | Oxidizing solids | Not applicable |
- |
- | - | Organic compounds containing no oxygen, fluorine or chlorine |
| 15 | Organic peroxides | Not applicable |
- |
- | - | Organic compounds containing no bivalent -O-O- structure in the molecule |
| 16 | Corrosive to metals | Classification not possible |
- |
- | - | Test methods applicable to solid substances are not available. |
| Hazard class | Classification |
Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 1 | Acute toxicity (Oral) | Not classified |
- |
- | - | Based on the LD50 value of > 10,000 mg/kg (SIDS (2002)) for rats, the substance was classified as "Not Classified." |
| 1 | Acute toxicity (Dermal) | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
| 1 | Acute toxicity (Inhalation: Gases) | Not applicable |
- |
- | - | Solid (GHS definition) |
| 1 | Acute toxicity (Inhalation: Vapours) | Not applicable |
- |
- | - | Solid (GHS definition) |
| 1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
| 2 | Skin corrosion/irritation | Not classified |
- |
- | - | In a skin irritation test according to US test guidelines (16 CFR 1500.41 - Method of testing primary irritant substances), in which this substance was applied for 24 hours, negative is reported (SIDS (2002)). Moreover, it was reported that it is nonirritating to the skin of rabbits (HSDB (Access on August 2016)). Therefore, the substance was classified as "Not classified." |
| 3 | Serious eye damage/eye irritation | Classification not possible |
- |
- | - |
Classification not possible due to lack of data. Besides, it is reported that this substance was assessed as non-irritating to the eyes in two independent tests using rabbits (HSDB (Access on August 2016), GESTIS (Access on July 2016)), however, the information was not adopted for the evidence of classification because details were not available. |
| 4 | Respiratory sensitization | Classification not possible |
- |
- | - | Classification not possible due to lack of data. Besides, it was reported that it evidently gave no evidence of sensitization in an animal study (HSDB (Access on August 2016)), but the information was not adopted for the evidence of classification because details on the test are not available. |
| 4 | Skin sensitization | Classification not possible |
- |
- | - | Classification not possible due to lack of data. Besides, it was reported that it evidently gave no evidence of sensitization in an animal study (HSDB (Access on August 2016)), but the information was not adopted for the evidence of classification because details on the test are not available. |
| 5 | Germ cell mutagenicity | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
| 6 | Carcinogenicity | Classification not possible |
- |
- | - | Classification not possible due to lack of data. Besides, it is described that no tumors were found after an 8-month administration to mice (SIDS (2002)). |
| 7 | Reproductive toxicity | Classification not possible |
- |
- | - |
In a preliminary reproduction toxicity screening test (OECD TG 421) using rats by an oral route (gavage administration), blue discoloration of feces and blue-green or grayish blue discolorations of the contents of the stomach and the intestines were noted in a F0 generation, but effects on fertility of parental animals and offspring were not observed up to 1,000 mg/kg/day (SIDS (2002), JECDB (Access on September 2016)). However, classification cannot be determined only by this result because this test is a screening test. There is no other data available for the classification. Classification is not possible from those reasons. |
| 8 | Specific target organ toxicity - Single exposure | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
| 9 | Specific target organ toxicity - Repeated exposure | Classification not possible |
- |
- | - |
No data available for humans. As for experimental animals, a 28-day repeated dose toxicity study using rats by gavage and 13-week repeated dose toxicity studies using rats or mice by feeding were performed, and no effects were observed within the range equivalent to Category 2 (SIDS (2002), JECDB (Access on September 2016)). However, the substance was classified as "Classification not possible" due to lack of data because there are no information etc. available for other routes. |
| 10 | Aspiration hazard | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
| Hazard class | Classification |
Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment (Acute) | Classification not possible |
- |
- | - | No data available. |
| 11 | Hazardous to the aquatic environment (Long-term) | Classification not possible |
- |
- | - | No data available. |
| 12 | Hazardous to the ozone layer | Classification not possible |
- |
- | - | No data available. |
|
* A blank or "-" in a cell of classification denotes that the classification of the hazard class was not conducted. * Hazard_statement_and/or_Precautionary_statement will show when hovering the mouse over a code of Hazard_statement_and/or_Precautionary_statement. Hazard_statement_and/or_Precautionary_statement are also provided in the Excel file. * Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. * Codes assigned to each of the hazard statements and codes for each of the precautionary statement are based on the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) in United Nations. |