GHS Classification Result
GENERAL INFORMATION
REFERENCE INFORMATION
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
GENERAL INFORMATION
| Item | Information |
|---|---|
| CAS RN | 7429-90-5 |
| Chemical Name | Aluminium metal |
| Substance ID | H27-B-015/C-036B_P |
| Classification year (FY) | FY2015 |
| Ministry who conducted the classification | Ministry of Health, Labour and Welfare (MHLW)/Ministry of the Environment (MOE) |
| New/Revised | Revised |
| Classification result in other fiscal year | FY2006 |
| Download of Excel format | Excel file |
REFERENCE INFORMATION
| Item | Information |
|---|---|
| Guidance used for the classification (External link) | GHS Classification Guidance for the Japanese Government (FY2013 revised edition (Ver. 1.1)) |
| UN GHS document (External link) | UN GHS document |
| Definitions/Abbreviations (Excel file) | Definitions/Abbreviations |
| Model Label by MHLW (External link) | MHLW Website (in Japanese Only) |
| Model SDS by MHLW (External link) | MHLW Website (in Japanese Only) |
| OECD/eChemPortal (External link) | eChemPortal |
| Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable |
- |
- | - | There are no chemical groups present in the molecule associated with explosive properties. |
| 2 | Flammable gases (including chemically unstable gases) | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
| 3 | Aerosols | Not applicable |
- |
- | - | Not an aerosol product. |
| 4 | Oxidizing gases | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
| 5 | Gases under pressure | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
| 6 | Flammable liquids | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
| 7 | Flammable solids | Not classified |
- |
- | - | Blockish aluminum is non-flammable (GESTIS (Access on July 2015)). Besides, it is written that finely dispersed particles are explosive in the air (ICSC (2000)). |
| 8 | Self-reactive substances and mixtures | Not applicable |
- |
- | - | There are no chemical groups present in the molecule associated with explosive or self-reactive properties. |
| 9 | Pyrophoric liquids | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
| 10 | Pyrophoric solids | Not classified |
- |
- | - | It is estimated that it does not ignite at normal temperatures from an ignition point of 590 degrees C (ICSC (2000)). |
| 11 | Self-heating substances and mixtures | Not classified |
- |
- | - | Blockish aluminum is non-flammable (GESTIS (Access on July 2015)). |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Category 2, Category 3 |
 Danger Warning |
H261 | P231+P232 P335+P334 P370+P378 P402+P404 P223 P280 P501 |
Blockish aluminum forms an oxide coating (alumite) in the air, and the inside does not corrode (Encyclopedic Dictionary of Chemistry). There is information that powder has a risk of fire and explosion in contact with water (ICSC (2000)). Aluminum powder (surface uncoated) is classified in class 4.3, PGII, III in UNRTDG (UN1396), corresponding to Category 2 or 3. |
| 13 | Oxidizing liquids | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
| 14 | Oxidizing solids | Not applicable |
- |
- | - | It is an inorganic substance. |
| 15 | Organic peroxides | Not applicable |
- |
- | - | It is an inorganic substance. |
| 16 | Corrosive to metals | Classification not possible |
- |
- | - | No established test method suitable for solid substances. |
| Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 1 | Acute toxicity (Oral) | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| 1 | Acute toxicity (Dermal) | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| 1 | Acute toxicity (Inhalation: Gases) | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
| 1 | Acute toxicity (Inhalation: Vapours) | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
| 1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| 2 | Skin corrosion/irritation | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| 3 | Serious eye damage/eye irritation | Classification not possible |
- |
- | - | The classification is not possible due to lack of data. Besides, it is written that dust of this substance may cause mild inflammation in eyes (HSDB (Access on June 2015)). |
| 4 | Respiratory sensitization | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| 4 | Skin sensitization | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| 5 | Germ cell mutagenicity | Classification not possible |
- |
- | - | The classification is not possible due to lack of data. There are no in vivo and in vitro data for metallic aluminum. |
| 6 | Carcinogenicity | Classification not possible |
- |
- | - | In 1970's, increased incidences of bladder and lung cancers were reported in workers at electrolysis tank of aluminum reduction plants. In IARC, working in the aluminum refining process is related to increased risk of cancers in workers, but it is estimated that the causative substance of cancers is not aluminum itself, but polycyclic aromatic hydrocarbon compounds, known carcinogens, or coal tar pitch volatiles, which are by-products derived from the decomposition of electrodes in the electrolysis tank. (IARC Suppl. 7 (1984), ACGIH (7th, 2008), ATSDR (2008)) As results of following epidemiological studies, some reports suggested a functional disorder of respiratory organs, or non-tumor lesions in respiratory organs by exposure to this substance, but there is no report on carcinogenicity (ACGIH (7th, 2008), ATSDR (2008)). Therefore, ACGIH classified in A4 (ACGIH (7th, 2008)). From the above, the substance was classified as "Classification not possible" in this hazard class. |
| 7 | Reproductive toxicity | Classification not possible |
- |
- | - | Due to no information on reproductive toxicity by exposure to this substance, the classification is not possible due to lack of data. Besides, it is reported that in a test in which aluminum chloride or aluminum lactate was dosed in an oral route to pregnant rats during a gestation period, or to neonatal rats on day 5-17 after birth, delayed neurobehavioral development or hypoactivity was observed in newborns (ACGIH (7th, 2008), ATSDR (2008)). |
| 8 | Specific target organ toxicity - Single exposure | Category 1 (respiratory organs) |
 Danger |
H370 | P308+P311 P260 P264 P270 P321 P405 P501 |
This substance (dust, powder) is irritating to the respiratory tract (HSDB (Access on June 2015)). As for humans, inhalation of this substance (dust) could cause lung disorder such as pneumoconiosis (aluminosis) (HSDB (Access on June 2015)). As for experimental animals, it is reported that in single inhalation exposure to this substance (dust) in rats, no change in pulmonary function but enzymatic and cytological changes in bronchoalveolar lavage fluid were observed at 0.05 mg/L, and microgranuloma development occurred in the lung and hilum lymph nodes (microscopic observation) at 0.2 mg/L. These were observed at doses corresponding to Category 1 (ACGIH (7th, 2008), PATTY (6th, 2012)). From the above, because this substance has effects on the respiratory organs in inhalation exposure, it was classified in Category 1 (respiratory system). Besides, respiratory tract irritation was included in effects on the respiratory organs. By adding new information, the previous classification was revised. |
| 9 | Specific target organ toxicity - Repeated exposure | Category 1 (respiratory organs) |
Danger |
H372 | P260 P264 P270 P314 P501 |
As for humans, in an epidemiological survey of 1,142 workers related to manufacturing aluminum and its compounds (1975-1981), effects on lung function were observed in exposure to dust of high concentration (> 100 mg/m3-year as total dust), and in chest X-ray examination, small and irregular nodes were reported in a lower part of the lung in 7-8% (ACGIH (7th, 2008)). As for experimental animals, there is no test report using this substance. Therefore, the substance was classified in Category 1 (respiratory system). Besides, as for humans, it is written that decreased cognitive test results were observed, but the clear conclusion was not be drawn (ATSDR (2008)). Moreover, it is written that aluminum is not a factor causing Alzheimer's disease at this time, and that in many studies, there is no consistent relationship between aluminum and nervous disorder (ACGIH (7th, 2008)). Therefore, central nervous system was not included in a target organ. |
| 10 | Aspiration hazard | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment (Acute) | Classification not possible |
- |
- | - | The classification is not possible because appropriate data are not obtained. |
| 11 | Hazardous to the aquatic environment (Long-term) | Classification not possible |
- |
- | - | No data. |
| 12 | Hazardous to the ozone layer | Classification not possible |
- |
- | - | No data. |
NOTE:
| * A blank or "-" in a cell of classification denotes that the classification of the hazard class was not conducted. * Hazard_statement_and/or_Precautionary_statement will show when hovering the mouse over a code of Hazard_statement_and/or_Precautionary_statement. Hazard_statement_and/or_Precautionary_statement are also provided in the Excel file. * Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. * Codes assigned to each of the hazard statements and codes for each of the precautionary statement are based on the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) in United Nations. |