GHS Classification Result
GENERAL INFORMATION
REFERENCE INFORMATION
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
GENERAL INFORMATION
| Item | Information |
|---|---|
| CAS RN | 19430-93-4 |
| Chemical Name | 3,3,4,4,5,5,6,6,6-Nonafluoro-1-hexene |
| Substance ID | H27-A-010, C-010A_P |
| Classification year (FY) | FY2015 |
| Ministry who conducted the classification | Ministry of Health, Labour and Welfare (MHLW)/Ministry of the Environment (MOE) |
| New/Revised | New |
| Classification result in other fiscal year | |
| Download of Excel format | Excel file |
REFERENCE INFORMATION
| Item | Information |
|---|---|
| Guidance used for the classification (External link) | GHS Classification Guidance for the Japanese Government (FY2013 revised edition (Ver. 1.1)) |
| UN GHS document (External link) | UN GHS document |
| Definitions/Abbreviations (Excel file) | Definitions/Abbreviations |
| Model Label by MHLW (External link) | MHLW Website (in Japanese Only) |
| Model SDS by MHLW (External link) | MHLW Website (in Japanese Only) |
| OECD/eChemPortal (External link) | eChemPortal |
| Hazard class | Classification |
Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable |
- |
- | - | There are no chemical groups present in the molecule associated with explosive properties. |
| 2 | Flammable gases (including chemically unstable gases) | Not applicable |
- |
- | - | "Liquids" according to GHS definition. |
| 3 | Aerosols | Not applicable |
- |
- | - | Not an aerosol product. |
| 4 | Oxidizing gases | Not applicable |
- |
- | - | "Liquids" according to GHS definition. |
| 5 | Gases under pressure | Not applicable |
- |
- | - | "Liquids" according to GHS definition. |
| 6 | Flammable liquids | Category 2 |
 Danger |
H225 |
P303+P361+P353
P370+P378 P403+P235 P210 P233 P240 P241 P242 P243 P280 P501 |
Baced on a flash point of -17 degrees C (closed cup) and a boiling point of 58 degrees C (ICSC (2008)), it was classified in Category 2. |
| 7 | Flammable solids | Not applicable |
- |
- | - | "Liquids" according to GHS definition. |
| 8 | Self-reactive substances and mixtures | Classification not possible |
- |
- | - | It contains a chemical group related to self-reactivity (ethylene group), but the classification is not possible due to no test data. |
| 9 | Pyrophoric liquids | Classification not possible |
- |
- | - | Due to no data, the classification is not possible. |
| 10 | Pyrophoric solids | Not applicable |
- |
- | - | "Liquids" according to GHS definition. |
| 11 | Self-heating substances and mixtures | Classification not possible |
- |
- | - | No established test method suitable for liquid substances. |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable |
- |
- | - | Not containing metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At). |
| 13 | Oxidizing liquids | Not applicable |
- |
- | - | It is an organic compound containing fluorine (but not chlorine or oxygen) which is not chemically bonded to the elements other than carbon or hydrogen. |
| 14 | Oxidizing solids | Not applicable |
- |
- | - | "Liquids" according to GHS definition. |
| 15 | Organic peroxides | Not applicable |
- |
- | - | It is an organic compound that does not contain bivalent -O-O- structure in the molecule. |
| 16 | Corrosive to metals | Classification not possible |
- |
- | - | Due to no data, the classification is not possible. |
| Hazard class | Classification |
Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 1 | Acute toxicity (Oral) | Not classified |
- |
- | - | Baced on a reported lethal dose of > 25 g/kg for rats (ACGIH (7th, 2004)), it was classified as "Not classified." |
| 1 | Acute toxicity (Dermal) | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| 1 | Acute toxicity (Inhalation: Gases) | Not applicable |
- |
- | - | "Liquids" according to GHS definition. |
| 1 | Acute toxicity (Inhalation: Vapours) | Classification not possible |
- |
- | - |
The classification is not possible due to lack of data. Besides, it is reported that although exposure time is unknown, toxic effects were not observed when mice were given by inhalation at 7,196 ppm (ACGIH (7th, 2004)). |
| 1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| 2 | Skin corrosion/irritation | Classification not possible |
- |
- | - |
The classification is not possible due to lack of data. Besides, there is the information that in a skin irritation test of the undiluted liquid of this substance using rabbits, it was not irritating (ACGIH (7th, 2004)), but no other information was obtained. Therefore, it was classified as "Classification not possible" due to lack of data. |
| 3 | Serious eye damage/eye irritation | Category 2B |
Warning |
H320 |
P305+P351+P338
P337+P313 P264 |
Baced on the information, without a detailed description, that in an eye irritation test applied this substance to rabbits, slight irritation was observed but it recovered within two days (ACGIH (7th, 2004)), it was classified in Category 2B. |
| 4 | Respiratory sensitization | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| 4 | Skin sensitization | Classification not possible |
- |
- | - |
The classification is not possible due to lack of data. Besides, it is reported that in a maximization test using guinea pigs (OECD TG 406), sensitization was not observed (ACGIH (7th, 2004)), but the details such as test conditions are unknown. |
| 5 | Germ cell mutagenicity | Classification not possible |
- |
- | - |
Due to no option of "Not classified" in the revised Classification Guidance, it was classified as "Classification not possible." As for in vivo, it is reported that a micronucleus test using mouse bone marrow cells was negative (ACGIH (7th, 2004)). Besides, as for in vitro, both a bacterial reverse mutation test and an HPRT test for gene mutation were negative (ACGIH (7th, 2004)). |
| 6 | Carcinogenicity | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| 7 | Reproductive toxicity | Classification not possible |
- |
- | - |
The classification is not possible due to lack of data. Besides, it is described that in an inhalation exposure test to this substance for pregnant rats, teratogenicity was not observed even at the dose where maternal toxicity (reduced weight gain, decreased food consumption) occurred. (ACGIH (7th, 2004), HSDB (Access on June 2015)) |
| 8 | Specific target organ toxicity - Single exposure | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| 9 | Specific target organ toxicity - Repeated exposure | Classification not possible |
- |
- | - |
There is no information on humans. As for experimental animals, there are data from a 2-week or 28-day inhalation toxicity test using rats and toxic effects by an inhalation route were not observed at the doses within guidance value range of up to Category 2. Besides, effects on the liver (hepatocellular vacuolization, decreased partial thromboplastin time) were found, however, the dose was out of the range of Category 2 (ACGIH (7th, 2004)). Because there is no toxic information in either other routes or humans, the substance was classified as "Classification not possible" due to lack of data. |
| 10 | Aspiration hazard | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| Hazard class | Classification |
Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment (Acute) | Classification not possible |
- |
- | - | No data. |
| 11 | Hazardous to the aquatic environment (Long-term) | Classification not possible |
- |
- | - | No data. |
| 12 | Hazardous to the ozone layer | Classification not possible |
- |
- | - | No data. |
NOTE:
|
* A blank or "-" in a cell of classification denotes that the classification of the hazard class was not conducted. * Hazard_statement_and/or_Precautionary_statement will show when hovering the mouse over a code of Hazard_statement_and/or_Precautionary_statement. Hazard_statement_and/or_Precautionary_statement are also provided in the Excel file. * Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. * Codes assigned to each of the hazard statements and codes for each of the precautionary statement are based on the Globally Harmonized System of Classification and Labelling of Chemicals iGHSj in United Nations. |