GHS Classification Result

Chemical Name:Methyl glycidyl ether
CAS:930-37-0

Result:
ID: 22A4148
Classifier: Ministry of Health, Labour and Welfare (MHLW), Ministry of the Environment (MOE)
Year Classified: FY2010
Reference Manual: GHS Classification Guidance by the Japanese Government (July, 2010)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecule.
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Liquid at room temperature (Tokyo Chemical Industry Co., Ltd. MSDS (Access on Sep. 2010)).
3 Aerosols Not applicable - - - - Not aerosol products.
4 Oxidizing gases Not applicable - - - - Liquid at room temperature (Tokyo Chemical Industry Co., Ltd. MSDS (Access on Sep. 2010)).
5 Gases under pressure Not applicable - - - - Liquid at room temperature (Tokyo Chemical Industry Co., Ltd. MSDS (Access on Sep. 2010)).
6 Flammable liquids Category 2 Danger H225: Highly flammable liquid and vapour P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P370+P378: In case of fire: Use ... for extinction.
P403+P235: Store in a well-ventilated place. Keep cool.
P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P233: Keep container tightly closed.
P240: Ground/bond container and receiving equipment.
P241: Use explosion-proof electrical/ventilating/lighting/.../equipment.
P242: Use only non-sparking tools.
P243: Take precautionary measures against static discharge.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P501: Dispose of contents/container to ...
Although measurement method of the flash point 18 degC is unknown (Gangolli (2nd, 1999)), it is estimated that the flash point measured by the closed-cup method is > 23 degC and initial boiling point reported < 113 degC (Lide (90th, 2009)) is > 35 degC. Therefore, the substance is classified into Category 2.
7 Flammable solids Not applicable - - - - Liquid at room temperature (Tokyo Chemical Industry Co., Ltd. MSDS (Access on Sep. 2010)).
8 Self-reactive substances and mixtures Classification not possible - - - - It contains chemical groups (epoxide group) associated with self-reactive properties in the molecule. Since no test results are available, classification is not possible.
9 Pyrophoric liquids Classification not possible - - - - No data available.
10 Pyrophoric solids Not applicable - - - - Liquid at room temperature (Tokyo Chemical Industry Co., Ltd. MSDS (Access on Sep. 2010)).
11 Self-heating substances and mixtures Classification not possible - - - - Test methods applicable to liquid substances are not available.
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable - - - - The chemical structure of the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13 Oxidizing liquids Not applicable - - - - The substance is an organic compound containing oxygen (but not fluorine or chlorine) which is chemically bonded only to carbon or hydrogen.
14 Oxidizing solids Not applicable - - - - Liquid at room temperature (Tokyo Chemical Industry Co., Ltd. MSDS (Access on Sep. 2010)).
15 Organic peroxides Not applicable - - - - Organic compounds containing no bivalent -O-O- structure.
16 Corrosive to metals Classification not possible - - - - No data available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Category 4 Warning H302: Harmful if swallowed P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P501: Dispose of contents/container to ...
Based on the rat LD50 value of 467 microL/kg (= 462 mg/kg) (RTECS (1998), original literature: National Technical Information Service. (Springfield, VA 22161), formerly U.S. Clearinghouse for Scientific & Technical Information. : OTS0536031), the substance was classified as Category 4.
1 Acute toxicity (Dermal) Category 3 Danger H311: Toxic in contact with skin P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P322: Specific treatment (see ... on this label).
P361: Remove/Take off immediately all contaminated clothing.
P363: Wash contaminated clothing before reuse.
P405: Store locked up.
P501: Dispose of contents/container to ...
Based on the rabbit LD50 value of 707 microL/kg (= 699 mg/kg) (RTECS (1998), original literature: National Technical Information Service. (Springfield, VA 22161), formerly U.S. Clearinghouse for Scientific & Technical Information. : OTS0536031), the substance was classified as Category 3.
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Liquid at room temperature (Tokyo Chemical Industry Co., Ltd. MSDS (Access on Sep. 2010))
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - - No data available.
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - - No data available.
2 Skin corrosion/irritation Classification not possible - - - - No data were available. As relevant notes, in the standard Draize test using rabbit, application of 500 microL of test substance for 24 hours caused severe irritation (RTECS (1998)).
3 Serious eye damage/eye irritation Classification not possible - - - - No data were available. As relevant notes, in the standard Draize test using rabbit, instillation of 10 microL of test substance caused moderate irritation (RTECS (1998)).
4 Respiratory sensitization Classification not possible - - - - No data available.
4 Skin sensitization Classification not possible - - - - In the guinea pig test, sensitization was observed in 2 of 49 animals (positive rate 4.1%) (HSDB (2002)). However, since the information was obtained from the "List 2" information source designated in the GHS classification guidance for the Japanese government and there was no description of the test method, the substance was classified as "Classification not possible".
5 Germ cell mutagenicity Classification not possible - - - - The classification was not possible due to lack of in vivo test data. As relevant information, as for in vitro study, positive results in the Ames test were reported (NTP DB (Access on Aug. 2010)).
6 Carcinogenicity Classification not possible - - - - No data available.
7 Reproductive toxicity Classification not possible - - - - No data available.
8 Specific target organ toxicity - Single exposure Classification not possible - - - - No data available.
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - No data available.
10 Aspiration hazard Classification not possible - - - - No data available.

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Classification not possible - - - - No data available.
11 Hazardous to the aquatic environment (Long-term) Classification not possible - - - - No data available.
12 Hazardous to the ozone layer Classification not possible - - - - This substance is not listed in Annexes to the Montreal Protocol.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model Label by MHLW

MHLW Website (in Japanese Only)

Model SDS by MHLW

MHLW Website (in Japanese Only)


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