NITE - Chemical Management Field

GHS Classification Result （Revision of the past classification result）

Chemical Name：Calcium hypochlorite
CAS：7778-54-3

Result：


ID:	21B3066
Classifier:	Ministry of Health, Labour and Welfare （MHLW）, Ministry of the Environment （MOE）
Year Classified:	FY2009
Reference Manual:	GHS Classification Guidance by the Japanese Government （March, 2009）

PHYSICAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Explosives	Not classified	-	-	-	-	The substance is classified into Division 5.1 in UNRTDG (UN1748).
2	Flammable gases （including chemically unstable gases）	Not applicable	-	-	-	-	Solid (room temperature)
3	Aerosols	Not applicable	-	-	-	-	Not aerosol products
4	Oxidizing gases	Not applicable	-	-	-	-	Solid (room temperature)
5	Gases under pressure	Not applicable	-	-	-	-	Solid (room temperature)
6	Flammable liquids	Not applicable	-	-	-	-	Solid (room temperature)
7	Flammable solids	Not classified	-	-	-	-	Not combustible (NPFA (13th, 2006), Hommel (1996), IUCLID (2000))
8	Self-reactive substances and mixtures	Not applicable	-	-	-	-	The substance is classified as Oxidizing solids.
9	Pyrophoric liquids	Not applicable	-	-	-	-	Solid (room temperature)
10	Pyrophoric solids	Not classified	-	-	-	-	Not combustible (NPFA (13th, 2006), Hommel (1996), IUCLID (2000))
11	Self-heating substances and mixtures	Not classified	-	-	-	-	Not combustible (NPFA (13th, 2006), Hommel (1996), IUCLID (2000))
12	Substances and mixtures which, in contact with water, emit flammable gases	Not applicable	-	-	-	-	The chemical structure of the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13	Oxidizing liquids	Not applicable	-	-	-	-	Solid (room temperature)
14	Oxidizing solids	Category 2		Danger	H272: May intensity fire; oxidizer	P370+P378: In case of fire: Use ... for extinction. P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P220: Keep/Store away from clothing/.../combustible materials. P221: Take any precaution to avoid mixing with combustibles/... P280: Wear protective gloves/protective clothing/eye protection/face protection. P501: Dispose of contents/container to ...	The substance is classified into Division 5.1, PG II in UNRTDG (UN1748).
15	Organic peroxides	Not applicable	-	-	-	-	Inorganic compound
16	Corrosive to metals	Classification not possible	-	-	-	-	Test methods applicable to solid (melting point >55 degC) substances are not available.

HEALTH HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Acute toxicity （Oral）	Category 4		Warning	H302: Harmful if swallowed	P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P330: Rinse mouth. P501: Dispose of contents/container to ...	Based on a LD50 value of 790 mg/kg for rats (male) (SIDS (2004)), the substance was classified into Category 4. [For health hazards, refer also to sodium hypochlorite.]
1	Acute toxicity （Dermal）	Not classified	-	-	-	-	Based on a LD50 value of >2000 mg/kg for rabbits (IUCLID (2000)), the substance was classified as "Not classified" in JIS Classification (correspond to Category 5 or "Not classified" in GHS classification).
1	Acute toxicity （Inhalation: Gases）	Not applicable	-	-	-	-	Solid (room temperature)
1	Acute toxicity （Inhalation: Vapours）	Classification not possible	-	-	-	-	No data available.
1	Acute toxicity （Inhalation: Dusts and mists）	Classification not possible	-	-	-	-	No data available.
2	Skin corrosion/irritation	Category 1		Danger	H314: Causes severe skin burns and eye damage	P301+P330+P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353: IF ON SKIN （or hair）: Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P310: Immediately call a POISON CENTER or doctor/physician. P321: Specific treatment （see ... on this label）. P363: Wash contaminated clothing before reuse. P405: Store locked up. P501: Dispose of contents/container to ...	Based on a report of "highly corrosive" to rabbit skin (IUCLID (2000)) and classification as C; R34 in EU classification (EU-Annex I (access on May 2009)), the substance was classified into Category 1.
3	Serious eye damage/eye irritation	Category 1		Danger	H318: Causes serious eye damage	P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P280: Wear protective gloves/protective clothing/eye protection/face protection. P310: Immediately call a POISON CENTER or doctor/physician.	Based on reports of "corrosive" to the eyes of test animals (IUCLID (2000)), superficial loss of epithelium from corneas and conjunctivas following experimental application to eyes of rabbits for 30 seconds (HSDB (2002)) and a pH of 11.5 (HSDB (2002)), the substance was classified into Category 1. As relevant information, the substance is also corrosive to the skin.
4	Respiratory sensitization	Classification not possible	-	-	-	-	No data available.
4	Skin sensitization	Category 1		Warning	H317: May cause an allergic skin reaction	P302+P352: IF ON SKIN: Wash with plenty of soap and water. P333+P313: If skin irritation or rash occurs: Get medical advice/attention. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P272: Contaminated work clothing should not be allowed out of the workplace. P280: Wear protective gloves/protective clothing/eye protection/face protection. P321: Specific treatment （see ... on this label）. P363: Wash contaminated clothing before reuse. P501: Dispose of contents/container to ...	Since the substance is on the Frosch contact allergen list (FROSCH, TEXTBOOK OF CONTACT DERMATITIS), the substance was classified into Category 1.
5	Germ cell mutagenicity	Not classified	-	-	-	-	Based on a negative result in a bone marrow micronucleus test by intraperitoneal injection to mice (in vivo somatic cell mutagenicity test) (SIDS (2004)), the substance was classified as "Not classified". As relevant information, from in vitro mutagenicity tests, there are reports of a positive chromosomal aberration test (SIDS (2004)) and a positive Ames tests (SIDS (2004)).
6	Carcinogenicity	Not classified	-	-	-	-	Based on the classifications of "Group 3" in IARC (IARC 52 (1991)), the substance was classified as "Not classified".
7	Reproductive toxicity	Classification not possible	-	-	-	-	Classification not possible due to lack of data. In a rat developmental test by oral administration during the organogenesis period, there were no effects on fetal development (IUCLID (2000)). In a one-generation reproductive toxicity test in rats, no reproductive toxicity was observed (SIDS (2004)). However, since hydrogen chloride or sodium hypochlorite was used in these tests, classification was not possible.
8	Specific target organ toxicity - Single exposure	Category 2 (respiratory system)		Warning	H371: May cause damage to organs (respiratory system)	P309+P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P405: Store locked up. P501: Dispose of contents/container to ...	Inhalation of hypochlorous acid fumes causes severe respiratory tract irritation and pulmonary edema (HSDB (2002)). Since the information is reported in a document in List 2, the substance was classified into Category 2 (respiratory system).
9	Specific target organ toxicity - Repeated exposure	Classification not possible	-	-	-	-	No data available.
10	Aspiration hazard	Classification not possible	-	-	-	-	No data available.

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
11	Hazardous to the aquatic environment （Acute）	Category 1		Warning	H400: Very toxic to aquatic life	P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ...	Classified into Category 1 from its 96h-LC50 = 0.06 mg free chlorine/L (0.12 mg/L as calcium hypochlorite) for fish (Rainbow trout and Channel catfish) (SIDS, 2006).
11	Hazardous to the aquatic environment （Long-term）	Category 1		Warning	H410: Very toxic to aquatic life with long lasting effects	P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ...	Classified into Category 1 since its acute toxicity is Category 1 and it is hard to forecast the behavior in water from which it varies with environmental conditions.
12	Hazardous to the ozone layer	Classification not possible	-	-	-	-	This substance is not listed in Annexes to the Montreal Protocol.

NOTE:

* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：

Reference Manual
Definitions / Abbreviations
Model Label by MHLW	MHLW Website （in Japanese Only）
Model SDS by MHLW	MHLW Website （in Japanese Only）