GHS Classification Result
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：Calcium peroxide
CAS：1305-79-9
Result：
| ID: | 21A3710 |
| Classifier: | Ministry of Health, Labour and Welfare （MHLW）, Ministry of the Environment （MOE） |
| Year Classified: | FY2009 |
| Reference Manual: | GHS Classification Guidance by the Japanese Government （March, 2009） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | Not classified | - | - | - | - | Classified into Not classified since the substance is classified into Division 5.1, PG II in UNRTDG (UN1457) though it contains chemical groups (-O-O-) associated with explosive properties present in the molecules. |
| 2 | Flammable gases （including chemically unstable gases） | Not applicable | - | - | - | - | Solid (GHS definition) |
| 3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products. |
| 4 | Oxidizing gases | Not applicable | - | - | - | - | Solid (GHS definition) |
| 5 | Gases under pressure | Not applicable | - | - | - | - | Solid (GHS definition) |
| 6 | Flammable liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
| 7 | Flammable solids | Not classified | - | - | - | - | Classified into Not classified since the substance is not flammable (Weiss (2nd, 1986)). |
| 8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | The substance is classified as Oxidizing agents. |
| 9 | Pyrophoric liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
| 10 | Pyrophoric solids | Not classified | - | - | - | - | Classified into Not classified since the substance is not flammble (Weiss (2nd, 1986)). |
| 11 | Self-heating substances and mixtures | Not classified | - | - | - | - | Classified into Not classified since the substance is not flammble (Weiss (2nd, 1986)). |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified | - | - | - | - | Classified into Not classified since it can be judged that the substance does not form combustible gas from the information of "Reacts very slowly with water at room temperature to form limewater and oxygen gas". |
| 13 | Oxidizing liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
| 14 | Oxidizing solids | Category 2 |
|
Danger | H272: May intensity fire; oxidizer |
P370+P378: In case of fire: Use ... for extinction. P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P220: Keep/Store away from clothing/.../combustible materials. P221: Take any precaution to avoid mixing with combustibles/... P280: Wear protective gloves/protective clothing/eye protection/face protection. P501: Dispose of contents/container to ... |
The substance is classified into Division 5.1, PG II in UNRTDG (UN1457). |
| 15 | Organic peroxides | Not applicable | - | - | - | - | Inorganic compound |
| 16 | Corrosive to metals | Classification not possible | - | - | - | - | Test methods applicable to solid substances are not available. |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Not classified | - | - | - | - | Based on LD50 values of >5400 mg/kg and 8640 mg/kg for rats (Pesticide safety information (Japan Crop Protection Association) (1994)), the substance was classified into "Not classified". |
| 1 | Acute toxicity （Dermal） | Not classified | - | - | - | - | Based on a LD50 value of >5400 mg/kg for rats (Pesticide safety information (Japan Crop Protection Association) (1994)), the substance was classified as "Not classified". |
| 1 | Acute toxicity （Inhalation: Gases） | Not applicable | - | - | - | - | Solid (GHS definition) |
| 1 | Acute toxicity （Inhalation: Vapours） | Classification not possible | - | - | - | - | No data available. |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Classification not possible | - | - | - | - | Classification not possible due to lack of data. As relevant information, a LC50 value was >1.75 mg/L/4h for rats (Pesticide safety information (Japan Crop Protection Association) (1994)). |
| 2 | Skin corrosion/irritation | Not classified | - | - | - | - | Since in a skin primary irritation test with rabbits where 0.5 g powder was applied on the skin for 4-hour, there were no changes in the skin at any observation time, the substance was considered not to be primary skin irritant (Pesticide safety information (Japan Crop Protection Association) (1994)). The substance was classified as "Not classified". |
| 3 | Serious eye damage/eye irritation | Category 1 |
|
Danger | H318: Causes serious eye damage |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P280: Wear protective gloves/protective clothing/eye protection/face protection. P310: Immediately call a POISON CENTER or doctor/physician. |
In an eye primary irritation test with rabbits where 0.1 g powder was applied into the eye, corneal opacity or cloudiness, iris congestion, conjunctival redness and chemosis occurred and persisted to day 21 in the unwashed eye group. Since these findings were attributed to strong alkali calcium hydroxide formed by the hydrolysis of calcium peroxide in the moisture condition of the eye (Pesticide safety information (Japan Crop Protection Association) (1994)), the substance was classified into Category 1. |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available. |
| 4 | Skin sensitization | Not classified | - | - | - | - | Based on a report of negative for skin sensitization in a guinea pig maximization test where some animals in the treated group and control group showed slight erythema but animals in the positive control group showed obvious erythema, crust formation and edema (Pesticide safety information (Japan Crop Protection Association) (1994)), the substance was classified as "Not classified". |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | Classification not possible due to lack of data from in vivo mutagenicity tests. From in vitro mutagenicity tests, there is a report of a negative Ames test (Pesticide safety information (Japan Crop Protection Association) (1994)). |
| 6 | Carcinogenicity | Classification not possible | - | - | - | - | No data available. |
| 7 | Reproductive toxicity | Classification not possible | - | - | - | - | No data available. |
| 8 | Specific target organ toxicity - Single exposure | Classification not possible | - | - | - | - | Although lethargy, piloerection and slight diuresis were observed immediately after oral administration of 8640 mg/kg to rats, these signs disappeared within 4 days and no gross pathological lesions were observed (Pesticide safety information (Japan Crop Protection Association)). Following dermal application to rats and mice at 5400 mg/kg, no abnormality was observed in general condition, treated area of the skin or necropsy (Pesticide safety information (Japan Crop Protection Association)). Additionally, when rats were exposed to 1.75 mg/L (dusts) by inhalation for 4-hour, no treatment-related death or signs were observed and the histopathological examination revealed no treatment-related findings (Pesticide safety information (Japan Crop Protection Association)). Based on the data, the substance corresponds to "Not classified" with oral and dermal exposures since no toxicity was observed at dose levels exceeding the upper limit of the guidance value range for Category 2. However, with inhalation routes, there are no data at a dose level near the cut-off value. Overall, classification was not possible. |
| 9 | Specific target organ toxicity - Repeated exposure | Classification not possible | - | - | - | - | No data available. |
| 10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available. |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Classification not possible | - | - | - | - | No data available. |
| 11 | Hazardous to the aquatic environment （Long-term） | Classification not possible | - | - | - | - | No data available. |
NOTE:
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* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
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Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website （in Japanese Only） |
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Model SDS by MHLW |
MHLW Website （in Japanese Only） |