|
Hazard class
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Classification
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Symbol
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Signal word
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Hazard statement
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Precautionary statement
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Rationale for the classification
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1
|
Acute toxicity （Oral）
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Classification not possible
|
-
|
-
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-
|
-
|
Classification not possible due to lack of data. As relevant information, LD50 values are 5790 mg/kg (RTECS (2003)) and 1800 mg/kg (GESTIS (access on Nov. 2009)) for rats.
|
|
1
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Acute toxicity （Dermal）
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Classification not possible
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-
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-
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-
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-
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No data available.
|
|
1
|
Acute toxicity （Inhalation: Gases）
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Not applicable
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-
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-
|
-
|
-
|
Solid (GHS definition)
|
|
1
|
Acute toxicity （Inhalation: Vapours）
|
Classification not possible
|
-
|
-
|
-
|
-
|
No data available.
|
|
1
|
Acute toxicity （Inhalation: Dusts and mists）
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Classification not possible
|
-
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-
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-
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-
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No data available.
|
|
2
|
Skin corrosion/irritation
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Classification not possible
|
-
|
-
|
-
|
-
|
Classification not possible due to lack of data. Although there is a report that when a 80% water-based paste was applied on the skin of rabbits, violet residues of the test substance were found after 24-hour and after 1 week. There were no signs of inflammation (GESTIS (access on Nov. 2009)). The original literature can not be confirmed and experimental details are not clear.
|
|
3
|
Serious eye damage/eye irritation
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Classification not possible
|
-
|
-
|
-
|
-
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Classification not possible due to lack of data. There is a result of "mild" irritating in a Draize test where 500 mg was applied to the skin of rabbits for 24-hour (RTECS (2003)). As information in a document in List 3, there is a report that application of 50 mg of substance into the conjunctival sac of rabbits resulted in slight irritation (reddening). Although the effect was noticeable after 1-hour and also after 24-hour (GESTIS (access on Nov. 2009)), the details are not clear.
|
|
4
|
Respiratory sensitization
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Classification not possible
|
-
|
-
|
-
|
-
|
No data available.
|
|
4
|
Skin sensitization
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Classification not possible
|
-
|
-
|
-
|
-
|
No data available.
|
|
5
|
Germ cell mutagenicity
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Classification not possible
|
-
|
-
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-
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-
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Classification not possible due to lack of data from in vivo mutagenicity tests. From in vitro mutagenicity tests, there are reports of a positive Ames test and a positive CHL cell chromosomal aberration test (Mutagenicity Test Data of Existing Chemical Substances based on the toxicity investigation system of the Industrial Safety and Health Law (1996)). In addition, the substance is an existing chemical substance, for which mutagenicity was established under the provisions of Article 57-3 of the Industrial Safety and Health Law
|
|
6
|
Carcinogenicity
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Classification not possible
|
-
|
-
|
-
|
-
|
No data available.
|
|
7
|
Reproductive toxicity
|
Classification not possible
|
-
|
-
|
-
|
-
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No data available.
|
|
8
|
Specific target organ toxicity - Single exposure
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Classification not possible
|
-
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-
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-
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-
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No data available.
|
|
9
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Specific target organ toxicity - Repeated exposure
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Classification not possible
|
-
|
-
|
-
|
-
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Classification not possible due to lack of data. As information in a document in List 3, there is a report of changes to the hemogram and functional changes to the liver and kidneys following oral administration to rats at 125 mg/kg for 30 days (GESTIS (access on Nov. 2009)), however, the details are not clear. Additionally, it was reported that as a consequence of repeated exposure of factory workers who handled anthraquinone and its derivatives, only irritation to the airways, functional changes to the nervous system and gastrointestinal complaints were reported, however signs of an incipient toxic pneumofibrosis were diagnosed by x-ray after long-term exposure (GESTIS (access on Nov. 2009)), however, the original literature can not be confirmed and the details are not clear.
|
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10
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Aspiration hazard
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Classification not possible
|
-
|
-
|
-
|
-
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No data available.
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