GHS Classification Result

Chemical Name:Calcium nitrate
CAS:10124-37-5

Result:
ID: 21A3552
Classifier: Ministry of Health, Labour and Welfare (MHLW), Ministry of the Environment (MOE)
Year Classified: FY2009
Reference Manual: GHS Classification Guidance by the Japanese Government (March, 2009)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not classified - - - - Classified into Not classified since the substance is classified into Division 5.1, PG III in UNRTDG (UN1454) though it contains chemical groups (N-O) associated with explosive properties present in the molecules.
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Solid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products.
4 Oxidizing gases Not applicable - - - - Solid (GHS definition)
5 Gases under pressure Not applicable - - - - Solid (GHS definition)
6 Flammable liquids Not applicable - - - - Solid (GHS definition)
7 Flammable solids Not classified - - - - Not combustible (Hommel (1996))
8 Self-reactive substances and mixtures Not applicable - - - - The substance is classified as Oxidizing solids.
9 Pyrophoric liquids Not applicable - - - - Solid (GHS definition)
10 Pyrophoric solids Not classified - - - - Not combustible (Hommel (1996))
11 Self-heating substances and mixtures Not classified - - - - Not combustible (Hommel (1996))
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - - The substance is estimated to be stable against water since data is available that water solubility is 121.2 g/100 mL (ICSC (2003)).
13 Oxidizing liquids Not applicable - - - - Solid (GHS definition)
14 Oxidizing solids Category 3 Warning H272: May intensity fire; oxidizer P370+P378: In case of fire: Use ... for extinction.
P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P220: Keep/Store away from clothing/.../combustible materials.
P221: Take any precaution to avoid mixing with combustibles/...
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P501: Dispose of contents/container to ...
The substance is classified into Division 5.1, PG III in UNRTDG (UN1454).
15 Organic peroxides Not applicable - - - - Inorganic compound
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Not classified - - - - Based on a LD50 value of 9285 mg/kg bw for rats (IUCLID (2000)), this substance was classified into "Not classified".
1 Acute toxicity (Dermal) Classification not possible - - - - Classification not possible due to lack of data. As relevant information, no toxic signs were observed in rats applied for 4-hour with test material (containing this substance at level of 81 - 93%) at 1000 mg/animal (correspond to 1.6 g/kg on the assumptions of body weights 200 g and substance purity of 81%).
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Solid (GHS definition)
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - - No data available.
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - - No data available.
2 Skin corrosion/irritation Classification not possible - - - - Animal test data are not available. There is a report that six farmers got corrosive wounds after contact with fertilizer (calcium nitrate), but the details on composition of the fertilizer, concentration, exposure time, etc. are not available (IUCLID (2000)), therefore, classification is not possible due to lack of data.
3 Serious eye damage/eye irritation Classification not possible - - - - No data available.
4 Respiratory sensitization Classification not possible - - - - No data available.
4 Skin sensitization Classification not possible - - - - No data available.
5 Germ cell mutagenicity Classification not possible - - - - Classification not possible due to lack of data. Although there are reports about gene mutation and micronucleus and chromosome aberration (IUCLID (2000)), the results are only reported as negative or equivocal and the details are not clear.
6 Carcinogenicity Classification not possible - - - - No data available.
7 Reproductive toxicity Classification not possible - - - - No data available.
8 Specific target organ toxicity - Single exposure Classification not possible - - - - No data available. As relevant information, for other water-soluble nitrates, there are reports that potassium nitrate may result in formation of methaemoglobin (ICSC (2009)) and that magnesium nitrate is a methemoglobin-forming agent (HSDB (2003)).
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - No data available. As relevant information, for other water-soluble nitrates, there is a report that methemoglobinemia was developed in humans following ingestion of potassium nitrate over a period of 12 days (HSDB (access on Jan. 2010)).
10 Aspiration hazard Classification not possible - - - - No data available.

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Not classified - - - - Classified into Not classified from its 96h-LC50 = 2400 mg/L for fish (Bluegill) (AQUIRE, 2010).
11 Hazardous to the aquatic environment (Long-term) Not classified - - - - Classified into Not classified since it is not non-water soluble (Very soluble in water, Merck 14th, 2006) and its acute toxicity is low.
12 Hazardous to the ozone layer Classification not possible - - - - This substance is not listed in Annexes to the Montreal Protocol.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model Label by MHLW

MHLW Website (in Japanese Only)

Model SDS by MHLW

MHLW Website (in Japanese Only)


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