GHS Classification Result (Revision of the past classification result)

Chemical Name:Nickel(II) nitrate
CAS:13138-45-9

Result:
ID: 20A2367
Classifier: Ministry of Health, Labour and Welfare (MHLW), Ministry of the Environment (MOE)
Year Classified: FY2008
Reference Manual: GHS Classification Guidance by the Japanese Government (Sep, 2008)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Classification not possible - - - - It belongs to nitrates and contains chemical groups associated with explosive properties. Since no further information is available, classification is not possible.
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Solid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products.
4 Oxidizing gases Not applicable - - - - Solid (GHS definition)
5 Gases under pressure Not applicable - - - - Solid (GHS definition)
6 Flammable liquids Not applicable - - - - Solid (GHS definition)
7 Flammable solid Not classified - - - - Not combustible (Hommel (1996))
8 Self-reactive substances and mixtures Not applicable - - - - The substance is oxidizing solid (UNRTDG Division 5.1, Packing group III).
9 Pyrophoric liquids Not applicable - - - - Solid (GHS definition)
10 Pyrophoric solids Not classified - - - - Not combustible (Hommel (1996))
11 Self-heating substances and mixtures Classification not possible - - - - Test methods applicable to solid substances with their melting points <= 140degC are not available.
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - - It is a metal compound, its water solubility is 99.2 g/100 g water at 25degC (Lide (84th, 2003)), and it is stable in contact with water (Weiss (2nd, 1986)).
13 Oxidizing liquids Not applicable - - - - Solid (GHS definition)
14 Oxidizing solids Category 3 Warning H272: May intensity fire; oxidizer P370+P378: In case of fire: Use ... for extinction.
P210: Keep away from heat/sparks/open flames/hot surfaces. ? No smoking.
P220: Keep/Store away from clothing/.../combustible materials.
P221: Take any precaution to avoid mixing with combustibles/...
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P501: Dispose of contents/container to ...
Since it is rated as Division 5.1, Packing group III by the UNRTDG (solid), the substance was classified into Category 3.
15 Organic peroxides Not applicable - - - - Inorganic compound
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Classification not possible - - - - No data available.
1 Acute toxicity (Dermal) Classification not possible - - - - No data available.
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Solid (GHS definition)
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - - No data available.
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - - No data available.
2 Skin corrosion/irritation Classification not possible - - - - No data available.
3 Serious eye damage/eye irritation Classification not possible - - - - No data available.
4 Respiratory sensitization Category 1 Danger H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled P304+P341: IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342+P311: If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P285: In case of inadequate ventilation wear respiratory protection.
P501: Dispose of contents/container to ...
It is rated as R42/43 in the EU classification. In addition, Nickel and its compounds are categorized into respiratory tract sensitizers (Group 2) in Recommendations of Occupational Exposure Limits (Japan Society for Occupational Health, 2008). Based on this information, the substance was classified into Category 1.
4 Skin sensitization Category 1 Warning H317: May cause an allergic skin reaction P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P333+P313: If skin irritation or rash occurs: Get medical advice/attention.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P272: Contaminated work clothing should not be allowed out of the workplace.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P321: Specific treatment (see ... on this label).
P363: Wash contaminated clothing before reuse.
P501: Dispose of contents/container to ...
It is rated as R42/43 in the EU classification. In addition, Nickel and its compounds are categorized into skin sensitizers (Group 1) in Recommendations of Occupational Exposure Limits (Japan Society for Occupational Health, 2008). Based on this information, the substance was classified into Category 1.
5 Germ cell mutagenicity Not classified - - - - Both dominant lethal tests using mice that received intraperitoneal administration (in vivo heritable mutagenicity tests using germ cells) and micronucleus assays (in vivo mutagenicity tests using somatic cell) produced negative results (EHC 108 (1991)). Based on these negative results, the substance was classified into the "Not classified" category. Regarding in vitro mutagenicity tests, Ames tests gave negative results (EHC 108 (1991)).
6 Carcinogenicity Category 1A Danger H350: May cause cancer P308+P313: IF exposed or concerned: Get medical advice/attention.
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P405: Store locked up.
P501: Dispose of contents/container to ...
It is rated as "Group 1" by the IARC (IARC 49 (1990)), "A1" by ACGIH (ACGIH (2001)), "Carc. Cat. 1" by EU (EU-Annex 1 (2009)), and "1" by Japan Society for Occupational Health (Recommendations of Occupational Exposure Limits (2008)). Based on these ratings, the substance was classified into Category 1A.
7 Reproductive toxicity Classification not possible - - - - No data available. See also health hazards associated with other nickel compounds (Nickel(II) chloride and nickel sulfate, etc.).
8 Specific target organ toxicity - Single exposure Classification not possible - - - - No data available. See also health hazards associated with other nickel compounds (Nickel(II) chloride and nickel sulfate, etc.).
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - No data available. See also health hazards associated with other nickel compounds (Nickel(II) chloride and nickel sulfate, etc.).
10 Aspiration hazard Classification not possible - - - - No data available.

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) - - - - - -
11 Hazardous to the aquatic environment (Long-term) - - - - - -


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model Label by MHLW

MHLW Website (in Japanese Only)

Model SDS by MHLW

MHLW Website (in Japanese Only)


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