GHS Classification Result

Chemical Name：Petrolatum; Petrolatum
CAS：8009-03-8

Result：
ID: 20A2246
Classifier: Ministry of Health, Labour and Welfare （MHLW）, Ministry of the Environment （MOE）
Year Classified: FY2008
Reference Manual: GHS Classification Guidance by the Japanese Government （Sep, 2008）

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Classification not possible - - - - Due to dissociation of nitrogen and oxygen from hydrocarbon through the formation of ammonia and water, the saturation of unsaturated bonds and the deposition and separation of its metal components by the catalysts during the hydrorefining process, the substance does not contain chemical groups associated with explosive properties.
2 Flammable gases （including chemically unstable gases） Not applicable - - - - The substance is a semi solid (Merck (14th, 2006)) and it is assumed to be a liquid at ordinary temperature.
3 Aerosols Not applicable - - - - Not aerosol products.
4 Oxidizing gases Not applicable - - - - The substance is a semi solid (Merck (14th, 2006)) and it is assumed to be a liquid at ordinary temperature.
5 Gases under pressure Not applicable - - - - The substance is a semi solid (Merck (14th, 2006)) and it is assumed to be a liquid at ordinary temperature.
6 Flammable liquids Not classified - - - - Since it is a semi solid (Merck (14th, 2006)) and its flash point is 182-221degC (ICSC (2002)), the substance was classified into "Not classified".
7 Flammable solid Not applicable - - - - The substance is a semi solid (Merck (14th, 2006)) and it is assumed to be a liquid at ordinary temperature.
8 Self-reactive substances and mixtures Not applicable - - - - Due to dissociation of nitrogen and oxygen from hydrocarbon through the formation of ammonia and water, the saturation of unsaturated bonds and the deposition and separation of its metal components by the catalysts during the hydrorefining process, the substance does not contain chemical groups associated with explosive or self-reactive properties.
9 Pyrophoric liquids Not classified - - - - Its autoignition point is > 290degC (ICSC (2002), ICSC (J) (2002)).
10 Pyrophoric solids Not applicable - - - - The substance is a semi solid (Merck (14th, 2006)) and it is assumed to be a liquid at ordinary temperature.
11 Self-heating substances and mixtures Classification not possible - - - - No data available.
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable - - - - Due to deposition and separation of its metal components by the catalysts during the hydrorefining process, the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, and At).
13 Oxidizing liquids Not applicable - - - - The substance is a semi solid (Merck (14th, 2006)) and it is assumed to be a liquid at ordinary temperature.
14 Oxidizing solids Not applicable - - - - The substance does not contain oxygen, fluorine or chlorine.
15 Organic peroxides Not applicable - - - - Organic compounds containing no bivalent -O-O- structure in the molecule
16 Corrosive to metals Classification not possible - - - - Its melting point is around 55degC; classification is not possible due to lack of data.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity （Oral） Classification not possible - - - - No data available.
1 Acute toxicity （Dermal） Classification not possible - - - - No data available. As relevant notes, its mixture with paraffin wax (CAS No. 8002-74-2) (1-to-1 ratio) has a rabbit LD50 value of 3600 mg/kg bw (IUCLID (2000)).
1 Acute toxicity （Inhalation: Gases） Not applicable - - - - The substance is a semi solid (Merck (14th, 2006)) and it is assumed to be a liquid at ordinary temperature.
1 Acute toxicity （Inhalation: Vapours） Classification not possible - - - - No data available.
1 Acute toxicity （Inhalation: Dusts and mists） Classification not possible - - - - No data available.
2 Skin corrosion/irritation Not classified - - - - According to Patty (5th, 2001), the substance is non-irritating, and it is documented to be used as a dermal test vehicle. Based on these reports, the substance was classified into "Not classified".
3 Serious eye damage/eye irritation Category 2B - Warning H320: Causes eye irritation P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/attention.
P264: Wash ... thoroughly after handling. 		Since the substance was evaluated to be slightly irritating in rabbits (IUCLID, (2000)), it was classified into Category 2B.
4 Respiratory sensitization Classification not possible - - - - No data available.
4 Skin sensitization Not classified - - - - Based on the following documents, the substance was classified into "Not classified": the substance was evaluated to be not sensitizing in humans (IUCLID (2000)); although dermatitis developed by repeated exposure, the substance was not sensitizing (IUCLID (2000)); and the substance is nonallergenic and is used as a dermal test vehicle (Patty (5th, 2001)).
5 Germ cell mutagenicity Classification not possible - - - - No data available.
6 Carcinogenicity Classification not possible - - - - In mixed diet tests using rats (FDRL, about 3000 mg/kg/day), no signs of carcinogenicity were detected in the application of either two kinds of white substances or one yellow substance (color differences were due to the degree of refinement) (EHC 20 (1982)). Similarly, the 80-week dermal administration tests using mice that were treated with 25 or 50 mg did not find signs of carcinogenicity (IUCLID (2000)). In addition, according to Patty, the highly refined substance showed little or no signs of carcinogenicity (Patty (5th, 2001)). Referring to the EU classification, the substance of low refinement (yellow, amber, and brown vaseline) is for industrial use, and it sometimes contains polycyclic aromatics that are carcinogenic, and therefore, it is rated as Category 2 (equivalent to Category 1B based on the JIS classification criteria) (EU-Annex 1 (accessed in September 2008)). Overall, since information on low-refined, yellow substance is not available, the substance was classified into "Classification not possible".
7 Reproductive toxicity Classification not possible - - - - No data available.
8 Specific target organ toxicity - Single exposure Classification not possible - - - - In a skin test using rabbits that were exposed to 4 ml/kg for 24 hours, toxic symptoms (abnormalities found in autopsy or systemic effects) were not recognized. However, test substance was a mixture with paraffin (CAS No. 8002-74-2) (1-to-1 ratio) (IUCLID (2000)). Since the information gathered was of this test and a hypodermic administration test only (IUCLID (2000)), the substance was classified into "Classification not possible" due to lack of data.
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - In 2-year mixed diet tests using rats (FDRL, about 3000 mg/kg/day, (90-day correction: 24000 mg/kg/day)), no toxic symptoms (abnormalities in behavior, mortality rate, blood items, urine, organs, and tissues) were detected in the application of either two kinds of white substances or one yellow substance (color differences were due to the degree of refinement) (IUCLID (2000)). This document indicates that the substance is to be rated as "Not classified" for oral administration; however, since no information on other routes is available, the substance was classified into "Classification not possible".
10 Aspiration hazard Classification not possible - - - - No data available.

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment （Acute） Classification not possible - - - - No data available.
11 Hazardous to the aquatic environment （Long-term） Classification not possible - - - - No data available.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：
Reference Manual
Definitions / Abbreviations
Model Label by MHLW

 MHLW Website （in Japanese Only）
Model SDS by MHLW

 MHLW Website （in Japanese Only）

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