Chemical Name：allyl methacrylate; 2-methyl-2-propenoic acid 2-propenyl ester
CAS：96-05-9

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Explosives	Not applicable	-	-	-	-	There are no chemical groups associated with explosive properties present in the molecules.
2	Flammable gases （including chemically unstable gases）	Not applicable	-	-	-	-	Liquid (GHS definition)
3	Aerosols	Not applicable	-	-	-	-	Not aerosol products.
4	Oxidizing gases	Not applicable	-	-	-	-	Liquid (GHS definition)
5	Gases under pressure	Not applicable	-	-	-	-	Liquid (GHS definition)
6	Flammable liquids	Category 3		Warning	H226: Flammable liquid and vapour	P303+P361+P353: IF ON SKIN （or hair）: Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P370+P378: In case of fire: Use ... for extinction. P403+P235: Store in a well-ventilated place. Keep cool. P210: Keep away from heat/sparks/open flames/hot surfaces. ? No smoking. P233: Keep container tightly closed. P240: Ground/bond container and receiving equipment. P241: Use explosion-proof electrical/ventilating/lighting/.../equipment. P242: Use only non-sparking tools. P243: Take precautionary measures against static discharge. P280: Wear protective gloves/protective clothing/eye protection/face protection. P501: Dispose of contents/container to ...	Since its flash point is 33degC (GESTIS (accessed in September 2008)), or 37degC (Chemical Risk Information Platform (CHRIP) (accessed in September 2008)), and 33degC (Lange (16th, 2005)), the substance was classified into Category 3.
7	Flammable solid	Not applicable	-	-	-	-	Liquid (GHS definition)
8	Self-reactive substances and mixtures	Classification not possible	-	-	-	-	Its acrylic groups are equivalent to unsaturated bonds. However, due to a lack of information, classification is not possible.
9	Pyrophoric liquids	Classification not possible	-	-	-	-	No data available.
10	Pyrophoric solids	Not applicable	-	-	-	-	Liquid (GHS definition)
11	Self-heating substances and mixtures	Classification not possible	-	-	-	-	Test methods applicable to liquid substances are not available.
12	Substances and mixtures which, in contact with water, emit flammable gases	Not applicable	-	-	-	-	The chemical structure of the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13	Oxidizing liquids	Not applicable	-	-	-	-	The substance contains oxygen (but not fluorine or chlorine) which is chemically bonded only to carbon or hydrogen.
14	Oxidizing solids	Not applicable	-	-	-	-	Liquid (GHS definition)
15	Organic peroxides	Not applicable	-	-	-	-	Organic compounds containing no bivalent -O-O- structure in the molecule
16	Corrosive to metals	Classification not possible	-	-	-	-	No data available.

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Acute toxicity （Oral）	Category 4		Warning	H302: Harmful if swallowed	P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P330: Rinse mouth. P501: Dispose of contents/container to ...	Since its rat LD50 value is 430 mg/kg (HSDB (2002)), the substance was classified into Category 4.
1	Acute toxicity （Dermal）	Category 3		Danger	H311: Toxic in contact with skin	P302+P352: IF ON SKIN: Wash with plenty of soap and water. P280: Wear protective gloves/protective clothing/eye protection/face protection. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P322: Specific treatment （see ... on this label）. P361: Remove/Take off immediately all contaminated clothing. P363: Wash contaminated clothing before reuse. P405: Store locked up. P501: Dispose of contents/container to ...	Since its rabbit LD50 value is 500 mg/kg (HSDB (2002)), the substance was classified into Category 3.
1	Acute toxicity （Inhalation: Gases）	Not applicable	-	-	-	-	Liquid (GHS definition)
1	Acute toxicity （Inhalation: Vapours）	Classification not possible	-	-	-	-	It is reported that its rat LC50 = 1.8 mg/L (RTECS (2006)), but its exposure time is not reported. Therefore, classification is not possible based only on this information.
1	Acute toxicity （Inhalation: Dusts and mists）	Classification not possible	-	-	-	-	No data available.
2	Skin corrosion/irritation	Category 2		Warning	H315: Causes skin irritation	P302+P352: IF ON SKIN: Wash with plenty of soap and water. P332+P313: If skin irritation occurs: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P321: Specific treatment （see ... on this label）. P362: Take off contaminated clothing and wash before reuse.	In a Draize test using rabbits, the substance was moderately irritating (RTECS (2006): 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 371, 1986). Therefore, it was classified into Category 2.
3	Serious eye damage/eye irritation	Not classified	-	-	-	-	In a Draize test using rabbits, redness of the conjunctivas was observed, and the total scores of three animals showing that symptom in 24 hours out of six animals were 4, 6, and 4, respectively, and all of them became 0 in four days (ECETOC TR48 (1998)). Since no injury would be observed in any of the animals within four days, the substance was classified into "Not classified".
4	Respiratory sensitization	Classification not possible	-	-	-	-	No data available.
4	Skin sensitization	Classification not possible	-	-	-	-	No data available.
5	Germ cell mutagenicity	Classification not possible	-	-	-	-	No data available.
6	Carcinogenicity	Classification not possible	-	-	-	-	No data available.
7	Reproductive toxicity	Classification not possible	-	-	-	-	No data available.
8	Specific target organ toxicity - Single exposure	Classification not possible	-	-	-	-	No data available.
9	Specific target organ toxicity - Repeated exposure	Classification not possible	-	-	-	-	It is reported that in an inhalation exposure test using rats for eight weeks, at the dose of 0.056 mg/L, weight changes of the urinary bladder, the spleen, and the thymus were noted (RTECS (2006)). But there is no other information available, and due to the lack of data, classification is not possible.
10	Aspiration hazard	Classification not possible	-	-	-	-	No data available.

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
11	Hazardous to the aquatic environment （Acute）	Category 1		Warning	H400: Very toxic to aquatic life	P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ...	Based on its 96h-LC50 = 0.99 mg/L for fish (fathead minnow) (AQUIRE, 2008), the substance was classified into Category 1.
11	Hazardous to the aquatic environment （Long-term）	Not classified	-	-	-	-	Although its preexisting classification for acute toxicity is Category 1, since it is rapidly biodegradable (readily biodegradable: based on each standard method; BOD degradability, 62%; TOC degradability, 95%; HPLC degradability, 100% (Biodegradation and Bioconcentration of Existing Chemical Substances under the Chemical Substances Control Law, 2001)) and its log Kow = 2.12 (PHYSPROP Database (2008)), the substance was classified into "Not classified".