GHS Classification Result

Chemical Name：Decanoic acid
CAS：334-48-5

Result：
ID: 1-256
Classifier: Ministry of Economy, Trade and Industry （METI）, Ministry of the Environment （MOE）
Year Classified: FY2008
Reference Manual: GHS Classification Guidance by the Japanese Government （Sep, 2008）

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecules.
2 Flammable gases （including chemically unstable gases） Not applicable - - - - Solid
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Solid
5 Gases under pressure Not applicable - - - - Solid
6 Flammable liquids Not applicable - - - - Solid
7 Flammable solids Classification not possible - - - - Classification not possible due to lack of data
8 Self-reactive substances and mixtures Not applicable - - - - There are no chemical groups associated with explosive or self-reactive properties present in the molecule.
9 Pyrophoric liquids Not applicable - - - - Solid
10 Pyrophoric solids Not classified - - - - Even if it contacts the normal temperature air, it does not ignite spontaneously (ignition temperature 377degC (Yaws,1997)).
11 Self-heating substances and mixtures Classification not possible - - - - The test method applicable for substances becoming liquid or gas at 140degC of test temperature has not been established.
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable - - - - Metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At) are not included.
13 Oxidizing liquids Not applicable - - - - Solid
14 Oxidizing solids Not applicable - - - - Although it is an organic compound including oxygen, not fluorine and chlorine, this oxygen has not chemically bound to any elements other than carbon and hydrogen.
15 Organic peroxides Not applicable - - - - The organic compound not including peroxy group in molecule.
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity （Oral） Not classified - - - - LD50 value 3,301 mg/kg of the oral administration test employing rat (JECFA (1998)), which corresponded to the U.N. GHS acute toxicity Category 5, fell under unadopted category in Japan and were classified into "Not classified".
1 Acute toxicity （Dermal） Not classified - - - - From a description of LD50 value of >5,000 mg/kg (Patty (5th, 2001)) in the dermal administration test employing rabbits, it was classified into "Not classified".
1 Acute toxicity （Inhalation: Gases） Not applicable - - - - Since it was a solid by the definition of GHS and inhalation in gas was not assumed, it was classified into "Not applicable".
1 Acute toxicity （Inhalation: Vapours） Classification not possible - - - - It is written that there is no mortality in 8-hour saturated steam exposure of rats (Patty (5th, 2001)). Since saturated vapor pressure level (25degC) is 0.0003 mg/L, LC50 value is presumed to be >0.0003 mg/L.. This value is in the range of the Category 1 of the vapor standard, and since classification cannot be specified, classification is not possible.
1 Acute toxicity （Inhalation: Dusts and mists） Classification not possible - - - - Classification not possible due to lack of data
2 Skin corrosion/irritation Category 2 Warning H315: Causes skin irritation P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P321: Specific treatment （see ... on this label）.
P362: Take off contaminated clothing and wash before reuse. 		Since there is a description, "moderately to severely irritating" (IUCLID (2000)) in the 24-hour administration study with rabbits, it was classified in Category 2.
3 Serious eye damage/eye irritation Category 1 Danger H318: Causes serious eye damage P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P310: Immediately call a POISON CENTER or doctor/physician. 		Since it has been described that the severe damages to corneal opacity, a conjunctiva, or the iris were seen in rabbits (IUCLID (2000)), and the damage fell level 9 (the highest level is 10.) for rabbits and the corneal injury after 72-hour would be level 10 (HSDB (2002)), it was classified into Category 1.
4 Respiratory sensitization Classification not possible - - - - Classification is not possible since there is no data.
4 Skin sensitization Not classified - - - - It was classified into "Not classified" from descriptions that skin sensitization was not observed in the patch test to humans (Patty (5th, 2001), IUCLID (2000)), and that skin sensitization was not indicated in the Buehler test employing 20 guinea pig (IUCLID (2000)).
5 Germ cell mutagenicity Classification not possible - - - - Although it is described as negative (Patty (5th, 2001), NTP DB (Access on September 2008)) in the Ames test employing in vitro bacterial cells, classification is not possible because there is no data of in vivo examination.
6 Carcinogenicity Classification not possible - - - - Since it is described that no evidence of carcinogenicityity is reported in the oral administration test employing rats (Patty (5th, 2001)) and no evaluation by major international evaluation agencies is made, classification is not possible.
7 Reproductive toxicity Classification not possible - - - - Classification not possible due to lack of data
8 Specific target organ toxicity - Single exposure Classification not possible - - - - Although it is described that excessive hypersalivation and diarrhea were seen and at high-dose (10,000 mg/kg), decline of nerve line control, and central nervous system control are seen in the oral administration test employing rats (IUCLID (2000)), it is the condition at the dose exceeding the guidance value of Category 2, and, classification is not possible due to insufficient data.
9 Specific target organ toxicity - Repeated exposure Not classified - - - - It has been described that the effects on stomach were not seen in 150 days oral administration test employing rats (Patty (5th, 2001)) and the effects on organ weights, liver, kidney were not seen in 102 days oral administration test employing dogs. (IUCLID (2000)). Since effects were not seen at the dose out of the range of the guidance value of Category 2 in both of them, it was classified into "Not classified ".
10 Aspiration hazard Classification not possible - - - - Classification not possible due to lack of data

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment （Acute） Category 3 - - H402: Harmful to aquatic life P273: Avoid release to the environment.
P501: Dispose of contents/container to ... 		It was classified into Category 3 from 72 hours EC50=12mg/L of the algae (Pseudokirchneriella subcapitata) (Environmental Agency eco-toxicity tests of chemicals (1998)).
11 Hazardous to the aquatic environment （Long-term） Category 3 - - H412: Harmful to aquatic life with long lasting effects P273: Avoid release to the environment.
P501: Dispose of contents/container to ... 		Since acute toxicity was Category 3, there were no data about rapid degradability and there were bio-accumulation (LogKow = 4.09 (PHYSPROP Database (2008))), it was classified into Category 3.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：
Reference Manual
Definitions / Abbreviations
Model Label by MHLW

 MHLW Website （in Japanese Only）
Model SDS by MHLW

 MHLW Website （in Japanese Only）

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