GHS Classification Result

Chemical Name：Ceramic fibres (alminosilicate)
CAS：

Result：
ID: 105
Classifier: Ministry of Health, Labour and Welfare （MHLW）, Ministry of the Environment （MOE）
Year Classified: FY2007
Reference Manual: GHS Classification Manual （10 Feb, 2006）
Technical Guidance Document on the GHS Classification （6 Dec, 2005）

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecules.
2 Flammable gases （including chemically unstable gases） Not applicable - - - - Solid
3 Aerosols Not applicable - - - - Not aerosol products.
4 Oxidizing gases Not applicable - - - - Solid
5 Gases under pressure Not applicable - - - - Solid
6 Flammable liquids Not applicable - - - - Solid
7 Flammable solids Not classified - - - - A nonflammable inorganic compound.
8 Self-reactive substances and mixtures Not applicable - - - - There are no chemical groups present in the molecule associated with explosive or self-reactive properties.
9 Pyrophoric liquids Not applicable - - - - Solid
10 Pyrophoric solids Not classified - - - - A nonflammable inorganic compound.
11 Self-heating substances and mixtures Not classified - - - - A nonflammable inorganic compound.
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - - It is a stable substance containing aluminum and silicon.
13 Oxidizing liquids Not applicable - - - - Solid
14 Oxidizing solids Not classified - - - - A stable silicate
15 Organic peroxides Not applicable - - - - Inorganic compound
16 Corrosive to metals Not classified - - - - A stable silicate

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity （Oral） Classification not possible - - - - No data available.
1 Acute toxicity （Dermal） Classification not possible - - - - No data available.
1 Acute toxicity （Inhalation: Gases） Not applicable - - - - Since the substance is a solid, it was classified into the "Not applicable" category.
1 Acute toxicity （Inhalation: Vapours） Classification not possible - - - - No data available.
1 Acute toxicity （Inhalation: Dusts and mists） Classification not possible - - - - No data available.
2 Skin corrosion/irritation Category 2 Warning H315: Causes skin irritation P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P321: Specific treatment （see ... on this label）.
P362: Take off contaminated clothing and wash before reuse. 		Based on the report that ceramic fibres cause skin irritation to workers who handle them (ACGIH, 2001), the substance was classified into Category 2.
3 Serious eye damage/eye irritation Classification not possible - - - - No data available.
4 Respiratory sensitization Classification not possible - - - - No data available.
4 Skin sensitization Classification not possible - - - - No data available.
5 Germ cell mutagenicity Classification not possible - - - - Regarding in vitro mutagenicity tests, a chromosomal aberration test using human embryonic lung cells gave positive results (IARC 81, 2002) and a micronucleus test using CHO cells also yielded positive results (IARC 81, 2002). However, since no appropriate in vivo test results are available, classification is not possible.
6 Carcinogenicity Category 2 Warning H351: Suspected of causing cancer P308+P313: IF exposed or concerned: Get medical advice/attention.
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P405: Store locked up.
P501: Dispose of contents/container to ... 		Refractory ceramic fibres are rated as "2B" by the IARC 81 (2002) and man-made mineral fibers (ceramic fibers and micro glass fibers) are rated as "2B" by the Japan Society for Occupational Health (2007). Based on these ratings, the substance was classified into Category 2. As additional background information, refractory ceramic fibres are rated as "A2" by the ACGIH (1996).
7 Reproductive toxicity Classification not possible - - - - No data available.
8 Specific target organ toxicity - Single exposure Category 3 （Respiratory tract irritation） Warning H335: May cause respiratory irritation (respiratory tract irritation) P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P271: Use only outdoors or in a well-ventilated area.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P405: Store locked up.
P501: Dispose of contents/container to ... 		Based on the report that ceramic fibres cause temporary upper respiratory tract irritation to workers who handle them (ACGIH, 2001), the substance was classified into Category 3 (respiratory tract irritation).
9 Specific target organ toxicity - Repeated exposure Category 1 (lung) Danger H372: Cause damage to organs through prolonged or repeated exposure (lung) P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P314: Get medical advice/attention if you feel unwell.
P501: Dispose of contents/container to ... 		In humans, a loss of forced vital capacity of the lung was noted in workers exposed to refractory ceramic fibres (IARC 81, 2002). In test animals, pulmonary fibrosis was found in rats that underwent inhalation exposure to 9 or 18 mg/m3 (75 or 120 fibres/cc; diameter, 1 micrometer; length, 30 micrometers) of ceramic fibres for 18 months (ACGIH, 2001). In male Syrian golden hamsters exposed for 18 months by nose-only inhalation for 6 hours per day on 5 days per week to 30 mg/m3 (approximately 220 fibres/cm3; diameter, 1 micrometer; length, 25 micrometers) or lower concentrations of ceramic fibres, inflammation of the lung was noted histologically as macrophage infiltration (IARC 81, 2002). Based on these reports, we determine that the lung is the target organ. Thus, the substance was classified into Category 1 (lung).
10 Aspiration hazard Classification not possible - - - - No data available.

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment （Acute） Classification not possible - - - - No data available.
11 Hazardous to the aquatic environment （Long-term） Classification not possible - - - - No data available.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：
Reference Manual
Definitions / Abbreviations

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