GHS Classification Result

Chemical Name:N-Nitrosodiethanolamine
CAS:1116-54-7

Result:
ID: 51
Classifier: Ministry of Health, Labour and Welfare (MHLW), Ministry of the Environment (MOE)
Year Classified: FY2007
Reference Manual: GHS Classification Manual (10 Feb, 2006)
Technical Guidance Document on the GHS Classification (6 Dec, 2005)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Classification not possible - - - - It contains chemical groups (N-nitroso group) associated with explosive properties. Since no test results are available, classification is not possible.
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Liquid (white - yellow oil (CRC))
3 Aerosols Not applicable - - - - Not aerosol products.
4 Oxidizing gases Not applicable - - - - Liquid (white - yellow oil (CRC))
5 Gases under pressure Not applicable - - - - Liquid (white - yellow oil (CRC))
6 Flammable liquids Classification not possible - - - - Classification is not possible due to insufficient test results available. (Its flash point is reported to be 11.6degC (IARC 77, 2000). According to the Industrial Safety and Health Act, the substance is designated as an inflammable dangerous substance.)
7 Flammable solids Not applicable - - - - Liquid (white - yellow oil (CRC))
8 Self-reactive substances and mixtures Classification not possible - - - - It contains chemical groups (N-nitroso group) associated with explosive properties. Since no test results are available, classification is not possible.
9 Pyrophoric liquids Classification not possible - - - - No data available.
10 Pyrophoric solids Not applicable - - - - Liquid (white - yellow oil (CRC))
11 Self-heating substances and mixtures Classification not possible - - - - No data available.
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable - - - - The chemical structure of the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13 Oxidizing liquids Classification not possible - - - - It is an organic compound containing oxygen (but not fluorine or chlorine), which is chemically bonded to nitrogen. Since no test results based on standardized testing methods are available, classification is not possible.
14 Oxidizing solids Not applicable - - - - Liquid (white - yellow oil (CRC))
15 Organic peroxides Not applicable - - - - Organic compounds containing no bivalent -O-O- structure
16 Corrosive to metals Classification not possible - - - - No data available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Not classified - - - - Based on the report that single oral administration of 7.5 g/kg bw of this substance did not kill rats (IARC 17, 1978), the substance was classified into the "Not classified" category.
1 Acute toxicity (Dermal) Classification not possible - - - - No data available.
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Solid
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - - No data available.
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - - No data available.
2 Skin corrosion/irritation Classification not possible - - - - No data available.
3 Serious eye damage/eye irritation Classification not possible - - - - No data available.
4 Respiratory sensitization Classification not possible - - - - No data available.
4 Skin sensitization Classification not possible - - - - No data available.
5 Germ cell mutagenicity Classification not possible - - - - Reverse mutation tests, which are a kind of in vitro mutagenicity test, gave positive results (IARC 77, 2000) and in vivo tests revealed DNA damage in rats (IARC 77, 2000) and mice (RTECS, accessed in October 2007). However, since no other in vivo test results are available, classification is not possible.
6 Carcinogenicity Category 2 Warning H351: Suspected of causing cancer P308+P313: IF exposed or concerned: Get medical advice/attention.
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P405: Store locked up.
P501: Dispose of contents/container to ...
It is rated as "Group 2B" by the IARC (1987), "2B" by Japan Society for Occupational Health (2007), "B2" by the U.S. EPA (1993), and "R" by the U.S. NTP (2005). Based on these ratings, the substance was classified into Category 2.
7 Reproductive toxicity Classification not possible - - - - No data available.
8 Specific target organ toxicity - Single exposure Classification not possible - - - - No data available.
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - No data available.
10 Aspiration hazard Classification not possible - - - - No data available.

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Classification not possible - - - - No data available.
11 Hazardous to the aquatic environment (Long-term) Classification not possible - - - - No data available.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model Label by MHLW

MHLW Website (in Japanese Only)

Model SDS by MHLW

MHLW Website (in Japanese Only)


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