GHS Classification Result
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：Dihypochlorous acid barium salt
CAS：13477-10-6
Result：
| ID: | 07-D36 |
| Classifier: | Ministry of Health, Labour and Welfare （MHLW）, Ministry of the Environment （MOE） |
| Year Classified: | FY2007 |
| Reference Manual: |
GHS Classification Manual （10 Feb, 2006） Technical Guidance Document on the GHS Classification （6 Dec, 2005） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | Classification not possible | - | - | - | - | It contains chemical groups (O-halogen) associated with explosive properties. However, since it is not used as explosives, no evaluation was carried out on this substance as explosives. Consequently, it was classified into the "Classification not possible" category. |
| 2 | Flammable gases （including chemically unstable gases） | Not applicable | - | - | - | - | Solid |
| 3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products. |
| 4 | Oxidizing gases | Not applicable | - | - | - | - | Solid |
| 5 | Gases under pressure | Not applicable | - | - | - | - | Solid |
| 6 | Flammable liquids | Not applicable | - | - | - | - | Solid |
| 7 | Flammable solids | Not classified | - | - | - | - | Nonflammable (SITTIG (4th 2002) p. 287) |
| 8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | It contains chemical groups (O-halogen) associated with explosive properties. However, since it is defined as an oxidizing substance, it does not fit the definition of self-reactive substances. Consequently, it was classified into the "Not applicable" category. |
| 9 | Pyrophoric liquids | Not applicable | - | - | - | - | Solid |
| 10 | Pyrophoric solids | Not classified | - | - | - | - | Nonflammable (SITTIG (4th 2002) p. 287) |
| 11 | Self-heating substances and mixtures | Not classified | - | - | - | - | Nonflammable (SITTIG (4th 2002) p. 287) |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified | - | - | - | - | Because the substance is rated as Division 5.1, Subsidiary Risks 6.1, packing group II, and not Division 4.3, by the UNRTDG, it was classified into the "Not classified" category. |
| 13 | Oxidizing liquids | Not applicable | - | - | - | - | Solid |
| 14 | Oxidizing solids | Category 2 |
|
Danger | H272: May intensity fire; oxidizer |
P370+P378: In case of fire: Use ... for extinction. P210: Keep away from heat/sparks/open flames/hot surfaces. ? No smoking. P220: Keep/Store away from clothing/.../combustible materials. P221: Take any precaution to avoid mixing with combustibles/... P280: Wear protective gloves/protective clothing/eye protection/face protection. P501: Dispose of contents/container to ... |
Since the substance containing higher than 22% available chlorine concentration by mass is rated as Division 5.1, Subsidiary Risks 6.1, packing group II (UN 2741) by the UNRTDG, it was classified into Category 2. |
| 15 | Organic peroxides | Not applicable | - | - | - | - | Inorganic substance |
| 16 | Corrosive to metals | Classification not possible | - | - | - | - | No data available. |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Classification not possible | - | - | - | - | No data available. Notes: According to the Japanese Government's GHS classification of calcium hypochlorite, which is similar in chemical structure to this substance, calcium hypochlorite is classified into Category 4 based on its rat LD50 of 850 mg/kg (RTECS, 2005; IUCLID, 2000; HSDB, 2005). |
| 1 | Acute toxicity （Dermal） | Classification not possible | - | - | - | - | No data available. Notes: According to the Japanese Government's GHS classification of calcium hypochlorite, which is similar in chemical structure to this substance, calcium hypochlorite is classified into Category 5 based on its rabbit LD50 of > 2000 mg/kg (IUCLID (2000)) and rabbit LDLo of 2000 mg/kg (RTECS (2005)). |
| 1 | Acute toxicity （Inhalation: Gases） | Not applicable | - | - | - | - | Solid |
| 1 | Acute toxicity （Inhalation: Vapours） | Classification not possible | - | - | - | - | No data available. |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Classification not possible | - | - | - | - | No data available. |
| 2 | Skin corrosion/irritation | Category 2 |
|
Warning | H315: Causes skin irritation |
P302+P352: IF ON SKIN: Wash with plenty of soap and water. P332+P313: If skin irritation occurs: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P321: Specific treatment （see ... on this label）. P362: Take off contaminated clothing and wash before reuse. |
Although no test results on this substance are available, barium and soluble compounds are reported to be skin irritants (ACGIH (2001)). In addition, barium is documented to be a mild skin irritant in rabbits (EHC 107 (1990)). Based on these reports, the substance was classified into Category 2. Notes: According to the Japanese Government's GHS classification of calcium hypochlorite, which is similar in chemical structure to this substance, calcium hypochlorite is classified into Category 1A-1C based on the following reports: it causes moderate to severe damage to the skin (HSDB (2005)); contact to it can severely irritate and burn the skin (HSFS (2003)); and it was found to be skin corrosive in rabbits (IUCLID (2000)). |
| 3 | Serious eye damage/eye irritation | Category 2A |
|
Warning | H319: Causes serious eye irritation |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. |
Although no test results on this substance are available, barium and soluble compounds are reported to be eye irritants (ACGIH (2001)). In addition, barium is documented to be a severe eye irritant in rabbits (EHC 107 (1990)). Based on these reports, the substance was classified into Category 2A. Notes: According to the Japanese Government's GHS classification of calcium hypochlorite, which is similar in chemical structure to this substance, calcium hypochlorite is classified into Category 1 based on reports that coming into contact with it can severely irritate and burn the eyes (HSFS (2003)) and it was found to be an eye corrosive in eye irritation tests with laboratory animals (IUCLID (2000)). |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available. |
| 4 | Skin sensitization | Classification not possible | - | - | - | - | No data available. |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | No data available. |
| 6 | Carcinogenicity | Classification not possible | - | - | - | - | No data available. |
| 7 | Reproductive toxicity | Classification not possible | - | - | - | - | No data available. |
| 8 | Specific target organ toxicity - Single exposure | Category 1 (gastrointestinal tract, skeletal muscle, heart) |
|
Danger | H370: Causes damage to organs (gastrointestinal tract, skeletal muscle, heart) |
P307+P311: IF exposed: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ... |
Although no test results on this substance are available, barium and soluble compounds are attributed to the stimulation of the gastrointestinal tract, myocardium, and other muscles (ACGIH (2001)). In addition, clinical features of barium poisoning include acute gastroenteritis and loss of deep reflexes with onset of skeletal muscular paralysis (EHC 107 (1990)). In animal experiments, the effects of barium ingestion include salivation, nausea, diarrhea, tachycardia, hypokalamia, twitching, flaccid paralysis of skeletal muscle, respiratory muscle paralysis, and ventricular fibrillation (EHC 107 (1990)). Based on these reports, the substance was classified into Category 1 (gastrointestinal tract, skeletal muscle, and heart). Notes: According to the Japanese Government's GHS classification of calcium hypochlorite, which is similar in chemical structure to this substance, calcium hypochlorite is classified into Category 2 (respiratory system) as its target organ was determined to be the respiratory system, based on the report that breathing calcium hypochlorite can irritate the lungs and may cause pulmonary edemas (HSDB (2005), HSFS (2003)) |
| 9 | Specific target organ toxicity - Repeated exposure | Category 2 (central nervous system, lung, heart, testis) |
|
Warning | H373: May cause damage to organs through prolonged or repeated exposure (central nervous system, lung, heart, testis) |
P260: Do not breathe dust/fume/gas/mist/vapours/spray. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ... |
Although no test results on this substance are available, repeated subcutaneous injections of barium chloride affected the central nervous system in rabbits, and repeated inhalation exposure induced interstitial pneumonitis in guinea pigs, rats, and hamsters (ACGIH (2001)). In addition, chronic exposure to barium compounds in drinking water or via inhalation affected the cardiac muscle and testes at doses that fall under Category 2 guidance values or higher doses (EHC 107 (1990)). Thus, the substance was classified into Category 2 (central nervous system, lung, heart, and testis). |
| 10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available. |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Classification not possible | - | - | - | - | No data available. |
| 11 | Hazardous to the aquatic environment （Long-term） | Classification not possible | - | - | - | - | No data available. |
NOTE:
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* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
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Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website （in Japanese Only） |
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Model SDS by MHLW |
MHLW Website （in Japanese Only） |