NITE - Chemical Management Field

GHS Classification Result

Chemical Name：Chlorobenzilate
CAS：510-15-6

Result：


ID:	1405
Classifier:	Inter-ministerial Committee on GHS
Year Classified:	FY2006
Reference Manual:	GHS Classification Manual （10 Feb, 2006）

PHYSICAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Explosives	Not applicable	-	-	-	-	Containing no chemical groups with explosive properties
2	Flammable gases （including chemically unstable gases）	Not applicable	-	-	-	-	Classified as "solid" according to GHS definition
3	Aerosols	Not applicable	-	-	-	-	Not aerosol products
4	Oxidizing gases	Not applicable	-	-	-	-	Classified as "solid" according to GHS definition
5	Gases under pressure	Not applicable	-	-	-	-	Classified as "solid" according to GHS definition
6	Flammable liquids	Not applicable	-	-	-	-	Classified as "solid" according to GHS definition
7	Flammable solids	Classification not possible	-	-	-	-	Classification not possible due to lack of data, though classified as flammable according to ICSC (2003)
8	Self-reactive substances and mixtures	Not applicable	-	-	-	-	Containing no chemical groups with explosive or self-reactive properties
9	Pyrophoric liquids	Not applicable	-	-	-	-	Classified as "solid" according to GHS definition
10	Pyrophoric solids	Classification not possible	-	-	-	-	No data available
11	Self-heating substances and mixtures	Classification not possible	-	-	-	-	No data available
12	Substances and mixtures which, in contact with water, emit flammable gases	Not applicable	-	-	-	-	Containing no metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At)
13	Oxidizing liquids	Not applicable	-	-	-	-	Classified as "solid" according to GHS definition
14	Oxidizing solids	Not applicable	-	-	-	-	Organic compounds containing oxygen and chlorine (but not fluorine), with the oxygen and chlorine bound to carbon and hydrogen (but not to other elements)
15	Organic peroxides	Not applicable	-	-	-	-	Organic compounds containing no "-O-O-" structure
16	Corrosive to metals	Classification not possible	-	-	-	-	No data available

HEALTH HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Acute toxicity （Oral）	Category 4		Warning	H302: Harmful if swallowed	P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P330: Rinse mouth. P501: Dispose of contents/container to ...	Based on the rat LD50 (oral route) value of 700mg/kg (RTECS (2006)).
1	Acute toxicity （Dermal）	Not classified	-	-	-	-	Based on the rat LD50 (dermal route) value of > 5,000mg/kg (RTECS (2006)).
1	Acute toxicity （Inhalation: Gases）	Not applicable	-	-	-	-	Due to the fact that the substance is a solid according to the GHS definition and inhalation of its gas is not expected.
1	Acute toxicity （Inhalation: Vapours）	Classification not possible	-	-	-	-	No data available
1	Acute toxicity （Inhalation: Dusts and mists）	Classification not possible	-	-	-	-	No data available
2	Skin corrosion/irritation	Category 3	-	Warning	H316: Causes mild skin irritation	P332+P313: If skin irritation occurs: Get medical advice/attention.	Based on the description in the report on rabbit skin irritation tests (exposure duration unknown) (RTECS (2006)): "Mildly irritating to the skin."
3	Serious eye damage/eye irritation	Category 2B	-	Warning	H320: Causes eye irritation	P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P264: Wash ... thoroughly after handling.	Based on the description in the report on rabbit eye irritation tests (RTECS (2006)): "Mildly irritating to the eye."
4	Respiratory sensitization	Classification not possible	-	-	-	-	No data available
4	Skin sensitization	Classification not possible	-	-	-	-	No data available
5	Germ cell mutagenicity	Classification not possible	-	-	-	-	Based on the absence of data on in vivo studies and no positive data on in vitro mutagenicity tests (several indices), described in NTP DB (Access on June 2006) and IARC 30 (1983).
6	Carcinogenicity	Not classified	-	-	-	-	Due to the fact that the substance is classified as Group 3 by IARC (1987).
7	Reproductive toxicity	Classification not possible	-	-	-	-	Classification not possible due to the insufficiency of data.
8	Specific target organ toxicity - Single exposure	Category 1 (central nervous system)		Danger	H370: Causes damage to organs (central nervous system)	P307+P311: IF exposed: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ...	Based on the human evidence including "ataxia, mild excitement/confusion" (IARC (1983)), and the evidence from animal studies including "ataxia, lacrimation, wheeze, laboured breathing and coma" (IARC 30 (1983)). The effects on experimental animals were observed at dosing levels within the guidance value ranges for Category 2.
9	Specific target organ toxicity - Repeated exposure	Category 2 (central nervous system, blood system)		Warning	H373: May cause damage to organs through prolonged or repeated exposure (central nervous system, blood system)	P260: Do not breathe dust/fume/gas/mist/vapours/spray. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ...	Based on the human evidence including "tonic-clonic epilepsy" (HSDB (2003)), and the evidence from animal studies including "moderate to severe anemia; extramedullary hematopoiesis of the liver and spleen and erythroid hyperplasia of the bone marrow" (IRIS (2003)), "depression with salivation, lacrimation, diarrhea, and deep rapid respiration" (HSDB (2003)). The effects on experimental animals were observed at dosing levels within the guidance value ranges for Category 2.
10	Aspiration hazard	Classification not possible	-	-	-	-	No data available

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
11	Hazardous to the aquatic environment （Acute）	Category 1		Warning	H400: Very toxic to aquatic life	P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ...	It was classified into Category 1 from 96 hours LC50=0.6mg/L of the fish (Rainbow Trout) (HSDB, 2004).
11	Hazardous to the aquatic environment （Long-term）	Category 1		Warning	H410: Very toxic to aquatic life with long lasting effects	P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ...	Since the acute toxicity was Category 1 and it had no rapidly degrading (the decomposition by BOD: 0% (Existing Chemicals Safety Check Data)), and it had the bio-accumulation (BCF=709 (Existing Chemicals Safety Check Data)), it was classified into Category 1.

NOTE:

* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：

Reference Manual
Definitions / Abbreviations
Model Label by MHLW	MHLW Website （in Japanese Only）
Model SDS by MHLW	MHLW Website （in Japanese Only）