Chemical Name:Sodium Pentachlorophenate
CAS:131-52-2
ID: | 1350 |
Classifier: | Inter-ministerial Committee on GHS |
Year Classified: | FY2006 |
Reference Manual: | GHS Classification Manual (10 Feb, 2006) |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
1 | Explosives | Not applicable | - | - | - | - | There are no chemical groups associated with explosive properties present in the molecules. |
2 | Flammable gases (including chemically unstable gases) | Not applicable | - | - | - | - | Solid (GHS definition) |
3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
4 | Oxidizing gases | Not applicable | - | - | - | - | Solid (GHS definition) |
5 | Gases under pressure | Not applicable | - | - | - | - | Solid (GHS definition) |
6 | Flammable liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
7 | Flammable solids | Not classified | - | - | - | - | Non-combustible (ICSC (J) (1997)) |
8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | There are no chemical groups associated with explosive or self-reactive properties present in the molecule. |
9 | Pyrophoric liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
10 | Pyrophoric solids | Not classified | - | - | - | - | Non-combustible (ICSC (J), 1997) |
11 | Self-heating substances and mixtures | Not classified | - | - | - | - | Not combustible (ICSC(J) (1997)) |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified | - | - | - | - | Stable to water (the water solubility is obtained) |
13 | Oxidizing liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
14 | Oxidizing solids | Not classified | - | - | - | - | UNRTDG No. 2567, Class: 6.1; PG II (Not 5.1). |
15 | Organic peroxides | Not applicable | - | - | - | - | Organic compounds containing no -0-0- structure |
16 | Corrosive to metals | Classification not possible | - | - | - | - | Test methods applicable to solid substances are not available. |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Category 3 | Danger | H301: Toxic if swallowed |
P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment (see ... on this label). P330: Rinse mouth. P405: Store locked up. P501: Dispose of contents/container to ... |
Category 3 based on SPECIES: Rat; ENDPOINT: LD50; VALUE: 71mg/kg; REFERENCE SOURCE: EHC 71 (1987) | |
1 | Acute toxicity (Dermal) | Category 2 | Danger | H310: Fatal in contact with skin |
P302+P350: IF ON SKIN: Gently wash with plenty of soap and water. P262: Do not get in eyes, on skin, or on clothing. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P280: Wear protective gloves/protective clothing/eye protection/face protection. P310: Immediately call a POISON CENTER or doctor/physician. P322: Specific treatment (see ... on this label). P361: Remove/Take off immediately all contaminated clothing. P363: Wash contaminated clothing before reuse. P405: Store locked up. P501: Dispose of contents/container to ... |
It was set as Category 2 based on rat LD50 =f 104mg/kg (EHC 71, 1987) of the dermal administration test. | |
1 | Acute toxicity (Inhalation: Gases) | Not applicable | - | - | - | - | Solid (GHS definition) |
1 | Acute toxicity (Inhalation: Vapours) | Not applicable | - | - | - | - | The vapor pressure of this substance is very low (it is 0.0000000036Pa at 25degC), and it was considered to be difficult to carry out vapor exposure. So it was out of a classification. |
1 | Acute toxicity (Inhalation: Dusts and mists) | Category 2 | Danger | H330: Fatal if inhaled |
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P284: Wear respiratory protection. P310: Immediately call a POISON CENTER or doctor/physician. P320: Specific treatment is urgent (see ... on this label). P405: Store locked up. P501: Dispose of contents/container to ... |
It was set as category 2 based on rat LC50 value 0.147mg/L/4H of an inhalation administration test (0.294mg/L/2H) (EHC 71, 1987). | |
2 | Skin corrosion/irritation | Category 2 | Warning | H315: Causes skin irritation |
P302+P352: IF ON SKIN: Wash with plenty of soap and water. P332+P313: If skin irritation occurs: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P321: Specific treatment (see ... on this label). P362: Take off contaminated clothing and wash before reuse. |
Since there is the description with redness and the pain which stimulate human skin (ICSC(J)1997; HSDB, 2003; SITTIG, 4th, 2002), and it was classified into R36/37/38 (eyes, respiratory systems and skin are stimulated) according to EU-Annex I (Accessed in Sept.2006), it was thought that there was skin irritation and it was set as category 2. | |
3 | Serious eye damage/eye irritation | Category 2A-2B | Warning | H319: Causes serious eye irritation |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. |
From the description with redness, pain and stimulate the human eye (ICSC(J), 1997; HSDB, 2003; SITTIG, 4th, 2002), and it is classified into R36/37/38( eye, respiratory organ, and skin are stimulated) according to Annex I (Accessed in Sept. 2006), it thought that there was eye irritation. And it was set as Category 2A-2B. In addition, detailed categorization is difficult. | |
4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available |
4 | Skin sensitization | Classification not possible | - | - | - | - | No data available |
5 | Germ cell mutagenicity | Not classified | - | - | - | - | There is no this substance data. But when based on the knowledge of pentachlorophenol (CAS No.87-86-5) (EHC 71, 1987), with an inadequate test, there was dominant fatality test negativity, no significant difference though the effect occurs by the mouse spot test, and Ames test negativity. So it is classified as the out of the Category, about this substance, sodium solt. |
6 | Carcinogenicity | Category 2 | Warning | H351: Suspected of causing cancer |
P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ... |
Since it was classified into carcinogenic category 3; R40 (evidence is restricted although carcinogenic concerns is caused to humans) in EU-Annex I (Accessed in Sept.2006). So it was set as 2. | |
7 | Reproductive toxicity | Category 2 | Warning | H361: Suspected of damaging fertility or the unborn child |
P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ... |
Since embryo absorption, fetal death and teratogenicity were observed at the dose indicating maternal toxicity in tests of oral mixed feed administration to 8-19 days pregnant female rats (EHC 71, 1987), it was set as Category 2. In addition, embryo and fetus toxicity is observed but not teratogenicity of pentachlorophenol (CAS: No.87-86-5) (EHC 71, 1987; HSG 19, 1989), although teratogenicity was seen in this study. | |
8 | Specific target organ toxicity - Single exposure | Category 2 (lung, cardiovascular system, central nervous system, liver, kidney) | Warning | H371: May cause damage to organs (lung, cardiovascular system, central nervous system, liver, kidney) |
P309+P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P405: Store locked up. P501: Dispose of contents/container to ... |
There is description that it affects human lungs, a cardiovascular system, a central nervous system, liver, and the kidney in ICSC (J)(1997), SITTIG (4th, 2002) of Priority 2 document, and it was considered as Category 2 (lungs, a cardiovascular system, a central nervous system, liver, kidney). In addition, there is description of influence on these internal organs as knowledge of pentachlorophenol (CAS No.87-86-5) in EHC 71 (1987). | |
9 | Specific target organ toxicity - Repeated exposure | Category 1 (skin, central nervous system, liver, kidney), Category 2 (central nervous system) |
Danger Warning |
H372: Cause damage to organs through prolonged or repeated exposure (skin, central nervous system, liver, kidney) H373: May cause damage to organs through prolonged or repeated exposure (central nervous system) |
P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ... |
Since there is the statement of influence into the human skin (chloracne), liver, and kidney (EHC 71 (1987) of Priority 1 document), it was classified into Category 1 (skin, liver, kidney). Since it is supposed that it has also effect on a central nervous systems besides these organs (ICSC (J) (1997) of Priority 2 document), it was classified into Category 2 (central nervous systems). | |
10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Category 1 | Warning | H400: Very toxic to aquatic life |
P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ... |
It was classified into Category 1 from 96-hour LC50=0.01mg/L of fishes (Carp) (EHC71, 1987). | |
11 | Hazardous to the aquatic environment (Long-term) | Category 1 | Warning | H410: Very toxic to aquatic life with long lasting effects |
P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ... |
Classified into Category 1, since acute toxicity was Category 1, supposed not rapidly degrading (BIOWIN), though supposed less bioaccumulative (log Kow=2.05 (PHYSPROP Database, 2005)). |
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
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Model SDS by MHLW |
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