GHS Classification Result

Chemical Name:barium di(acetate)
CAS:543-80-6

Result:
ID: 1331
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual (10 Feb, 2006)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecules.
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Solid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Solid (GHS definition)
5 Gases under pressure Not applicable - - - - Solid (GHS definition)
6 Flammable liquids Not applicable - - - - Solid (GHS definition)
7 Flammable solids Not classified - - - - Non-combustible (ICSC (J) (2001))
8 Self-reactive substances and mixtures Not applicable - - - - There are no chemical groups associated with explosive or self-reactive properties present in the molecule.
9 Pyrophoric liquids Not applicable - - - - Solid (GHS definition)
10 Pyrophoric solids Not classified - - - - Non-combustible (ICSC (J), 2001)
11 Self-heating substances and mixtures Not classified - - - - Not combustible (ICSC(J) (2001))
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - - Stable to water (the water solubility is obtained)
13 Oxidizing liquids Not applicable - - - - Solid (GHS definition)
14 Oxidizing solids Classification not possible - - - - No data available
15 Organic peroxides Not applicable - - - - Inorganic compound
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Category 4 Warning H302: Harmful if swallowed P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P501: Dispose of contents/container to ...
Category 4 based on SPECIES: Rat; ENDPOINT: LD50; VALUE: 921mg/kg; REFERENCE SOURCE: RTECS (2004)
1 Acute toxicity (Dermal) Classification not possible - - - - No data available
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Solid (GHS definition)
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - - No data available
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - - No data available
2 Skin corrosion/irritation Classification not possible - - - - Data without. In addition, there is description with a stimulus (ACGIH-TLV, 2005) about the skin as a water-soluble barium compounds.
3 Serious eye damage/eye irritation Classification not possible - - - - Without Data. In addition, there is description with a stimulus (ACGIH-TLV, 2005) about an eye as a water-soluble barium compounds.
4 Respiratory sensitization Classification not possible - - - - No data available
4 Skin sensitization Classification not possible - - - - No data available
5 Germ cell mutagenicity Classification not possible - - - - No data available
6 Carcinogenicity Classification not possible - - - - No data available
7 Reproductive toxicity Classification not possible - - - - No data available
8 Specific target organ toxicity - Single exposure Category 1 (digestive system, heart, muscle), Category 2 (nervous system) Danger
Warning
H370: Causes damage to organs (digestive system, heart, muscle)
H371: May cause damage to organs (nervous system)
P307+P311: IF exposed: Call a POISON CENTER or doctor/physician.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P309+P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician.
It was considered as Category 1 (a digestive systems, the heart, muscles) and Category 2 (nervous system) based on the description that gastrointestinal irritation, muscle disorder (ACGIH-TLV, 2005), gastroenteritis, hypokalemia, high blood pressure, arrhythmia, and skeletal muscle paralysis (CICAD 33, 2001) are caused as a water-soluble barium compounds, gastrointestinal tract were affwcted, and organs (the heart, a nervous system and muscles) were affected by the fall of potassium levels in blood, paralysis of muscles, abnormal heart rhythm, and a respiratory failure may be produced by short-term exposure to humans (ICSC (J), 2001).
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - Although proteinuria was extensively observed in the male rat in the long-term administrations tests in drinking water to the rat (EHC 107, 1990) and the renal effect was suggested, it could not be classified due to insufficient data.
10 Aspiration hazard Classification not possible - - - - No data available

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Classification not possible - - - - Insufficient data available.
11 Hazardous to the aquatic environment (Long-term) Classification not possible - - - - Classification not possible due to lack of data


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model Label by MHLW

MHLW Website (in Japanese Only)

Model SDS by MHLW

MHLW Website (in Japanese Only)


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