GHS Classification Result

Chemical Name:tin difluoride
CAS:7783-47-3

Result:
ID: 1280
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual (10 Feb, 2006)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecules.
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Solid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Solid (GHS definition)
5 Gases under pressure Not applicable - - - - Solid (GHS definition)
6 Flammable liquids Not applicable - - - - Solid (GHS definition)
7 Flammable solids Not classified - - - - Non-combustible (ICSC (J) (2004))
8 Self-reactive substances and mixtures Not applicable - - - - There are no chemical groups associated with explosive or self-reactive properties present in the molecule.
9 Pyrophoric liquids Not applicable - - - - Solid (GHS definition)
10 Pyrophoric solids Not classified - - - - Non-combustible (ICSC (J), 2004)
11 Self-heating substances and mixtures Not classified - - - - Not combustible (ICSC(J) (2004))
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - - Stable to water (the water solubility is obtained)
13 Oxidizing liquids Not applicable - - - - Solid (GHS definition)
14 Oxidizing solids Classification not possible - - - - No data available
15 Organic peroxides Not applicable - - - - Inorganic compound
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Category 3 Danger H301: Toxic if swallowed P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P321: Specific treatment (see ... on this label).
P330: Rinse mouth.
P405: Store locked up.
P501: Dispose of contents/container to ...
Based on the rat oral LD50 values : 360mg/kg (RTECS, 2004) and 200-300mg/kg (HSDB, 2003), we adopted the lower value (200-300mg/kg) to classify the substance as Category 3.
1 Acute toxicity (Dermal) Classification not possible - - - - No data available
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Solid (GHS definition)
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - - No data available
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - - No data available
2 Skin corrosion/irritation Classification not possible - - - - There is the description that effect was not acknowledged by the coating of the 0.1% solution (DFGOT 14, 2000) or 0.5% solution (CICAD 65, 2005) to the rabbit skin. But data is insufficient and it cannot be classified.
3 Serious eye damage/eye irritation Category 2A-2B Warning H319: Causes serious eye irritation P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
From the description that eye irritation was indicated with this product (ICSC, 2004), and eye irritation was indicated with inorganic tin compounds (ACGIH-TLV(2006)), it was set as Category 2A-2B. In addition, detailed categorization is difficult.
4 Respiratory sensitization Classification not possible - - - - No data available
4 Skin sensitization Classification not possible - - - - No data available
5 Germ cell mutagenicity Not classified - - - - There is the negativity in the mouse small core test (CICAD 65, 2005;DFGOT 14, 2000), it is classified as the out of the Category. In addition, there is a slightly positive reports in in vitro mutagenicity test (Ames test) (CICAD 65, 2005; DFGOT 14, 2000; RTRCS, 2004). But it is not regarded as a result with the reliability instead of the reaction under a general condition (CICAD 65, 2005).
6 Carcinogenicity Classification not possible - - - - In the assessment including the this product, IARC set fluoride to Group 3 (CICAD 65, 2005;HSDB, 2003), and ACGIH set fluoride to A4(ACGIH-TLV, 2006) (neither of them can not be classified as a human carcinogen). However, IARC did not carry out the carcinogenicity assessment of the tin compounds nor the first tin of fluoridation. Therefore, it is presupposed that it cannot be classified since data is insufficient.
7 Reproductive toxicity Classification not possible - - - - Although effect was not seen in the rat generating toxicity test by pregnancy term medication (CICAD 65, 2005), the effect on reproduction ability is unknown. And since its data is insufficient, it cannot be classified.
8 Specific target organ toxicity - Single exposure Category 3 (Respiratory tract irritation) Warning H335: May cause respiratory irritation (respiratory tract irritation) P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P271: Use only outdoors or in a well-ventilated area.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P405: Store locked up.
P501: Dispose of contents/container to ...
Although there was no data of this product, since it was supposed that an inorganic tin compound indicates respiratory irritant, it was considered as Category 3 (respiratory irritant) in ACGIH-TLV (2006).
9 Specific target organ toxicity - Repeated exposure Category 1 (lung, bone, tooth) Danger H372: Cause damage to organs through prolonged or repeated exposure (lung, bone, tooth) P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P314: Get medical advice/attention if you feel unwell.
P501: Dispose of contents/container to ...
This product may affect a tooth or a bone (fluorosis) (ICSC, 2004), and it is supposed that it has a possibility of pneumoconiosis by as an inorganic tin compound, and has an effect on bone of fluorosis by as fluoride (ACGIH-TLV (2006)). Therefore, it was classified into Category 1 (lungs, bones, tooth). In addition, descriptions of "expression of benign pneumoconiosis" and "dental caries prophylaxis" are seen in SEISYO.
10 Aspiration hazard Classification not possible - - - - No data available

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Classification not possible - - - - No data available
11 Hazardous to the aquatic environment (Long-term) Classification not possible - - - - No data available.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model Label by MHLW

MHLW Website (in Japanese Only)

Model SDS by MHLW

MHLW Website (in Japanese Only)


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