GHS Classification Result

Chemical Name:Silicate(2-), hexafluoro-, disodium
CAS:16893-85-9

Result:
ID: 1199
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual (10 Feb, 2006)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecules.
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Solid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Solid (GHS definition)
5 Gases under pressure Not applicable - - - - Solid (GHS definition)
6 Flammable liquids Not applicable - - - - Solid (GHS definition)
7 Flammable solids Not classified - - - - Non-combustible (ICSC (J) (1994))
8 Self-reactive substances and mixtures Not applicable - - - - There are no chemical groups associated with explosive or self-reactive properties present in the molecule.
9 Pyrophoric liquids Not applicable - - - - Solid (GHS definition)
10 Pyrophoric solids Not classified - - - - Non-combustible (ICSC (J), 1994)
11 Self-heating substances and mixtures Not classified - - - - Not combustible (ICSC(J) (1994))
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - - Stable to water (the water solubility is obtained)
13 Oxidizing liquids Not applicable - - - - Solid (GHS definition)
14 Oxidizing solids Not classified - - - - UNRTDG No. 2674, Class: 6.1; PG III (Not 5.1).
15 Organic peroxides Not applicable - - - - Inorganic compound
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Category 3 Danger H301: Toxic if swallowed P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P321: Specific treatment (see ... on this label).
P330: Rinse mouth.
P405: Store locked up.
P501: Dispose of contents/container to ...
Based on the LD50 = 125mg/kg in the oral administration tests with rats (RTECS, 2003; IUCLID, 2000; HSDB, 2003), the substance was classified as Category 3.
1 Acute toxicity (Dermal) Classification not possible - - - - No data available
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Solid (GHS definition)
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - - No data available
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - - No data available
2 Skin corrosion/irritation Category 3 - Warning H316: Causes mild skin irritation P332+P313: If skin irritation occurs: Get medical advice/attention. From the description of redness and the pain which stimulate the human skin (ICSC, 1994;SITTIG, 2002) and the description of a mild degree stimulus and weak congestion in the rabbit skin (RTECS, 2003;IUCLID, 2000), it thought that there was mild irritation and it was set as category 3.
3 Serious eye damage/eye irritation Category 2A Warning H319: Causes serious eye irritation P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
Due to the descriptions that it irritates to the eye, causes redness and pain (ICSC, 1994;SITTIG, 2002), and that irritates to rabbit eye and the obstacle to cornea (RTECS, 2003;IUCLID, 2000), it was classified into Category 2A.
4 Respiratory sensitization Classification not possible - - - - No data available
4 Skin sensitization Classification not possible - - - - No data available
5 Germ cell mutagenicity Classification not possible - - - - There is no result of in vivo mutagenicity test and there is the result that the in vitro mutagenicity test (Ames test) is negative (IUCLID, 2000). But it cannot be classified because of insufficient data.
6 Carcinogenicity Classification not possible - - - - Although fluoride was classified into A4 (corresponding to outer Category) in ACGIH-TLV (2005), due to insufficient data, it cannot be classified.
7 Reproductive toxicity Classification not possible - - - - Although there is no developmental toxicity in fluoride according to MAK/BAT (2005), it cannot be classified since data is insufficient.
8 Specific target organ toxicity - Single exposure Category 2 (heart), Category 3 (respiratory tract irritation) Warning H371: May cause damage to organs (heart)
H335: May cause respiratory irritation (respiratory tract irritation)
P309+P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P405: Store locked up.
P501: Dispose of contents/container to ...
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P271: Use only outdoors or in a well-ventilated area.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
It was considered as Category 2 (heart) base on the description that "calcium metabolism is affected and a heart problem is produced" in ICSC (1994) of Priority 2 document. Moreover, it was considered as Category 3 (respiratory irritant) based on the description that fluoride has an airway irritation in ACGIH-TLV (2005) of Priority 1 document, in addition, "an airway is stimulated" in ICSC (1994) of priority 2 document.
9 Specific target organ toxicity - Repeated exposure Category 1 (bone) Danger H372: Cause damage to organs through prolonged or repeated exposure (bone) P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P314: Get medical advice/attention if you feel unwell.
P501: Dispose of contents/container to ...
It is classified into Category 1 (bone) based on the description of th effect on a bone (fluorosis) of fluoride (ACGIH-TLV (2005) of Priority 1 document), and in addition, the description of "a bone is affected and fluorosis is occured" (ICSC (1994) of priority 2 document).
10 Aspiration hazard Classification not possible - - - - No data available

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Category 3 - - H402: Harmful to aquatic life P273: Avoid release to the environment.
P501: Dispose of contents/container to ...
It was classified into Category 3 from 96-hour LC50=49000microg/L of fishes (Bluegill) (AQUIRE, 2003).
11 Hazardous to the aquatic environment (Long-term) Category 3 - - H412: Harmful to aquatic life with long lasting effects P273: Avoid release to the environment.
P501: Dispose of contents/container to ...
Classified into Category 3, since acute toxicity was Category 3, and behavior in water and bioaccumulative potential are unknown.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model Label by MHLW

MHLW Website (in Japanese Only)

Model SDS by MHLW

MHLW Website (in Japanese Only)


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