GHS Classification Result

Chemical Name：potassium nitrite
CAS：7758-09-0

Result：
ID: 1111
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual （10 Feb, 2006）

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not classified - - - - Not classified based on UNRTDG No. 1488, Class: 5.1, PGIII, though being nitrates containing N-O bonds as chemical groups associated with explosive properties present. "The substance has a high reactivity and could explode by the contact of various substances, fire, or heat." (ICSC(J), 200; Sax, 11th, 2004)
2 Flammable gases （including chemically unstable gases） Not applicable - - - - Solid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Solid (GHS definition)
5 Gases under pressure Not applicable - - - - Solid (GHS definition)
6 Flammable liquids Not applicable - - - - Solid (GHS definition)
7 Flammable solids Not classified - - - - Nonflammable (ICSC (J), 2000). (However, this product is highly reactive and combustion is promoted by a contact with other substance. (ICSC(J), 2000))
8 Self-reactive substances and mixtures Not applicable - - - - Classified in oxidizing solids
9 Pyrophoric liquids Not applicable - - - - Solid (GHS definition)
10 Pyrophoric solids Not classified - - - - Non-combustible (ICSC (J), 2000)
11 Self-heating substances and mixtures Not classified - - - - Not combustible (ICSC(J) (2000))
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - - Stable to water (the water solubility is obtained)
13 Oxidizing liquids Not applicable - - - - Solid (GHS definition)
14 Oxidizing solids Category 2 Danger H272: May intensity fire; oxidizer P370+P378: In case of fire: Use ... for extinction.
P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P220: Keep/Store away from clothing/.../combustible materials.
P221: Take any precaution to avoid mixing with combustibles/...
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P501: Dispose of contents/container to ... 		UNRTDG No. 1488, Class: 5.1; PG II.
15 Organic peroxides Not applicable - - - - Inorganic compound
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity （Oral） Classification not possible - - - - Classification not possible due to lack of data
1 Acute toxicity （Dermal） Classification not possible - - - - No data available
1 Acute toxicity （Inhalation: Gases） Not applicable - - - - Solid (GHS definition)
1 Acute toxicity （Inhalation: Vapours） Classification not possible - - - - No data. (It is a solid. And there is no vapor pressure information, and it is unknown whether exposure to vapor is possible.)
1 Acute toxicity （Inhalation: Dusts and mists） Category 5 - Warning H333: May be harmful if inhaled P304+P312: IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. It was set as Category 5 based on mouse LC50 value 42mg/L/4H (85g/m3/2H) (RTECS, 1997).
2 Skin corrosion/irritation Category 2 Warning H315: Causes skin irritation P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P321: Specific treatment （see ... on this label）.
P362: Take off contaminated clothing and wash before reuse. 		It was set as category 2 from the description that "reddening of the skin which stimulates the skin violently." (ICSC, 2000; SITTIG, 2002; HSFS, 2004)
3 Serious eye damage/eye irritation Category 2B - Warning H320: Causes eye irritation P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/attention.
P264: Wash ... thoroughly after handling. 		Due to the description that "it irritates to the eye, causes redness and pain" (ICSC, 2000; SITTIG, 2002), and it was classified into Category 2B.
4 Respiratory sensitization Classification not possible - - - - No data available
4 Skin sensitization Classification not possible - - - - No data available
5 Germ cell mutagenicity Classification not possible - - - - Although the in vitro mutagenicity test (RTECS, 1997) was positive, there being no examination data of in vivo mutagenicity. So it was presupposed that it cannot classify.
6 Carcinogenicity Classification not possible - - - - No data available
7 Reproductive toxicity Category 2 Warning H361: Suspected of damaging fertility or the unborn child P308+P313: IF exposed or concerned: Get medical advice/attention.
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P405: Store locked up.
P501: Dispose of contents/container to ... 		There were two reports as for reproductive potential study of rats and guinea pig (RTECS(1997)), although the description about the general toxicity of those parental animals did not have, reproductive toxicity was manifestated (the influence on a fertility, a miscarriage, stillbirth), and it was set as Category 2.
8 Specific target organ toxicity - Single exposure Category 2 (cardiovascular system, blood), Category 3 (respiratory tract irritation) Warning H371: May cause damage to organs (cardiovascular system, blood)
H335: May cause respiratory irritation (respiratory tract irritation) 		P309+P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P405: Store locked up.
P501: Dispose of contents/container to ...
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P271: Use only outdoors or in a well-ventilated area.
P312: Call a POISON CENTER or doctor/physician if you feel unwell. 		The substance was classified as Category 2 (cardio-vascular system, blood) and Category 3 (airway irritant) based on the reports in Priority 2 documents of the effects on the cardio-vascular system (ICSC, 2000; RTECS, 1997), and of the effects on blood (formation of methemoglobin) (ICSC, 2000; HSFS, 2004), and of airway irritant properties (ICSC, 2000; SITTIG, 2002; HSFS, 2004) in humans.
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - Although there is the description of the influence on the skin, the respiratory system, the liver, and the kidney of humans (SITTIG (4th, 2002) and HSFS (2004) of Priority 2 document), there is no data which is supported, and it cannot be classifyied due to insufficient data.
10 Aspiration hazard Classification not possible - - - - No data available

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment （Acute） Classification not possible - - - - Insufficient data available.
11 Hazardous to the aquatic environment （Long-term） Classification not possible - - - - Classification not possible due to lack of data


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：
Reference Manual
Definitions / Abbreviations
Model Label by MHLW

 MHLW Website （in Japanese Only）
Model SDS by MHLW

 MHLW Website （in Japanese Only）

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