GHS Classification Result
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：sulphuryl difluoride
CAS：2699-79-8
Result：
| ID: | 1096 |
| Classifier: | Inter-ministerial Committee on GHS |
| Year Classified: | FY2006 |
| Reference Manual: | GHS Classification Manual （10 Feb, 2006） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable | - | - | - | - | Gas (GHS definition) |
| 2 | Flammable gases （including chemically unstable gases） | Not classified | - | - | - | - | Non-combustible (ICSC(J), 2001) |
| 3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
| 4 | Oxidizing gases | Not classified | - | - | - | - | Not classified because it is UNRTDG No. 2191, Class: 2.3(8) but not Subsidiary risks Class: 5.1. |
| 5 | Gases under pressure | Liquefied gas |
|
Warning | H280: Contains gas under pressure; may explode if heated | P410+P403: Protect from sunlight. Store in a well-ventilated place. | Liquefied gas because of "the critical temp: -20 or 96degC" (HSDB, 2002). |
| 6 | Flammable liquids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 7 | Flammable solids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | Gas (GHS definition) |
| 9 | Pyrophoric liquids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 10 | Pyrophoric solids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 11 | Self-heating substances and mixtures | Not applicable | - | - | - | - | Gas (GHS definition) |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | Gas (GHS definition) |
| 13 | Oxidizing liquids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 14 | Oxidizing solids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 15 | Organic peroxides | Not applicable | - | - | - | - | Gas (GHS definition) |
| 16 | Corrosive to metals | Classification not possible | - | - | - | - | Test methods applicable to gas substances are not available |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Category 3 |
|
Danger | H301: Toxic if swallowed |
P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment （see ... on this label）. P330: Rinse mouth. P405: Store locked up. P501: Dispose of contents/container to ... |
Category 3 based on SPECIES: Rat; ENDPOINT: LD50; VALUE: 100 mg/kg; REFERENCE SOURCE: RTECS(2004) |
| 1 | Acute toxicity （Dermal） | Classification not possible | - | - | - | - | No data available |
| 1 | Acute toxicity （Inhalation: Gases） | Category 3 |
|
Danger | H331: Toxic if inhaled |
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P311: Call a POISON CENTER or doctor/physician. P321: Specific treatment （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ... |
Rad LC50 value (4-hour equivalent) = 1865ppm (male) and 1510ppm (female) (all are ACGIH(s) (7th, 2001)) (in the information on Priority 1), and the higher toxic value (1510ppm) was adopted, and it was considered as Category 3. |
| 1 | Acute toxicity （Inhalation: Vapours） | Not applicable | - | - | - | - | Gas (GHS definition) |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Not applicable | - | - | - | - | Gas (GHS definition) |
| 2 | Skin corrosion/irritation | Category 2 |
|
Warning | H315: Causes skin irritation |
P302+P352: IF ON SKIN: Wash with plenty of soap and water. P332+P313: If skin irritation occurs: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P321: Specific treatment （see ... on this label）. P362: Take off contaminated clothing and wash before reuse. |
There is no data about skin corrosivity/stimulativeness. It was set as category 2 in order to call attention, since chilblain may be started by touching the liquid when the this product is in state of a compressed liquefied gas (ICSC (J), (2001), SITTIG (4th, 2002)). |
| 3 | Serious eye damage/eye irritation | Category 2A-2B |
|
Warning | H319: Causes serious eye irritation |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. |
Although there is the description that it irritates to human eyes (ACGIH (7th, 2001), SITTIG (4th, 2002), ICSC (J), (2001), HSFS (2000)), its level of irritation is unknown. Therefore, it was classified into Category 2A-2B. [Indication] 2A is recommended based on the safety, when the Category needs to subdivide. |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available |
| 4 | Skin sensitization | Classification not possible | - | - | - | - | No data available |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | No data available |
| 6 | Carcinogenicity | Classification not possible | - | - | - | - | No data available |
| 7 | Reproductive toxicity | Classification not possible | - | - | - | - | Although a teratogenic effects was not acknowledged in rats and rabbits (Catalog of Teratogenic Agents, 11th ed. (2004)), there is no data which performed evaluation to the fertility of this product and it cannot be classified for the insufficient data. . |
| 8 | Specific target organ toxicity - Single exposure | Category 1 (central nervous system), Category 2 (respiratory system) |
|
Danger Warning |
H370: Causes damage to organs (central nervous system) H371: May cause damage to organs (respiratory system) |
P307+P311: IF exposed: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ... P309+P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician. |
The substance was classified as Category 1 (central nervous system) because there is a report in Priority 1 that "it affects the central nervous system" in humans (ACGIH (7th, 2001)), and there are also mentions of effects CNS in the ACGIH-TLV (2005). The substance was also classified as Category 2 (respiratory system) because there are reports concerning humans in Priority 2 that it "causes serious irritation to the airways," "inhalation of the gas may cause pulmonary edema," etc. (ICSC (J) (2001), SITTIG (4th, 2002). |
| 9 | Specific target organ toxicity - Repeated exposure | Category 2 (kidney, respiratory system, central nervous system, tooth/bone) |
|
Warning | H373: May cause damage to organs through prolonged or repeated exposure (kidney, respiratory system, central nervous system, tooth/bone) |
P260: Do not breathe dust/fume/gas/mist/vapours/spray. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ... |
In the evaluation report of Priority 1, it is described that the result of the repetitive toxicity examination to a rat and a rabbit is effect on the kidney, respiratory tract, a central nervous system, and a tooth (fluorosis) in the inhalation of 300 ppm / 6 h/day (partially 100 ppm / 6 h/day) (5 days/wk) (ACGIH (7th, 2001)). Since this figure is almost equivalent to the guidance value which helps the classification to Category 2 and in an assessment report of Priority 2 to human, the influence to the kidney and fluorosis (tooth/bone) are occdured (SITTIG (4th, 2002)), it was classified into Category 2 (the kidney, respiratory tract, central nervous system, tooth/bone). |
| 10 | Aspiration hazard | Not applicable | - | - | - | - | Gas (GHS definition) |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Classification not possible | - | - | - | - | No data available |
| 11 | Hazardous to the aquatic environment （Long-term） | Classification not possible | - | - | - | - | No data available. |
NOTE:
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* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
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Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website （in Japanese Only） |
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Model SDS by MHLW |
MHLW Website （in Japanese Only） |