GHS Classification Result

Chemical Name：sodium selenite
CAS：10102-18-8

Result：
ID: 1063
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual （10 Feb, 2006）

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecules.
2 Flammable gases （including chemically unstable gases） Not applicable - - - - Solid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Solid (GHS definition)
5 Gases under pressure Not applicable - - - - Solid (GHS definition)
6 Flammable liquids Not applicable - - - - Solid (GHS definition)
7 Flammable solids Classification not possible - - - - Although ICSC (J) (1998) has the description "it is a flammable under specific conditions", the conditions or examination data are not available. And data is insufficient, it cannot be classified.
8 Self-reactive substances and mixtures Not applicable - - - - There are no chemical groups associated with explosive or self-reactive properties present in the molecule.
9 Pyrophoric liquids Not applicable - - - - Solid (GHS definition)
10 Pyrophoric solids Not classified - - - - Even if it contacts the normal temperature air, it does not ignite spontaneously. (Merck (13th, 2001) has the description "It is stabilized in the air".)
11 Self-heating substances and mixtures Classification not possible - - - - No data available
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - - Stable to water (the water solubility is obtained)
13 Oxidizing liquids Not applicable - - - - Solid (GHS definition)
14 Oxidizing solids Classification not possible - - - - No data available
15 Organic peroxides Not applicable - - - - Inorganic compound
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity （Oral） Category 2 Danger H300: Fatal if swallowed P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P321: Specific treatment （see ... on this label）.
P330: Rinse mouth.
P405: Store locked up.
P501: Dispose of contents/container to ... 		SPECIES: Rat ENDPOINT: LD50 VALUE: 7mg/kg REFERENCE SOURCE: RTECS(2004)
1 Acute toxicity （Dermal） Classification not possible - - - - No data available
1 Acute toxicity （Inhalation: Gases） Not applicable - - - - Solid (GHS definition)
1 Acute toxicity （Inhalation: Vapours） Classification not possible - - - - No data available
1 Acute toxicity （Inhalation: Dusts and mists） Classification not possible - - - - No data available
2 Skin corrosion/irritation Category 2 Warning H315: Causes skin irritation P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P321: Specific treatment （see ... on this label）.
P362: Take off contaminated clothing and wash before reuse. 		It was thought that there was stronger skin stimulativeness by the description in the humans (redness, a burn, discoloration, etc.) (ICSC (J) (1998), SITTIG (4th, 2002), and HSFS (2002)), and it was set as Category 2.
3 Serious eye damage/eye irritation Category 2A Warning H319: Causes serious eye irritation P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection. 		It is considered that there is strong stimulativeness to the eye in human from the description (redness, pain, damage, etc.) ( ACGIH-TLV (2004), ICSC (J), (1998), SITTIG (4th, 2002), and HSFS (2002)), and it was classified into Category 2A.
4 Respiratory sensitization Classification not possible - - - - No data available
4 Skin sensitization Classification not possible - - - - Suppose that there is possibility of skin sensitization in the class of EU-Annex I (Access on May 2005). Although there is a case report which suggests human skin sensitization also in HSDB (2002), and there is the description of the human contact dermatitis in ICSC(J)(1998), since data is insufficient, it cannot classify.
5 Germ cell mutagenicity Category 2 Warning H341: Suspected of causing genetic defects P308+P313: IF exposed or concerned: Get medical advice/attention.
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P405: Store locked up.
P501: Dispose of contents/container to ... 		Although there was positive reports (PATTY, 5th, 2001) of a somatic cell in vivo mutagenicity test (mouse bone marrow chromosomal aberration test), there was no report of a productive cell in vivo heredity toxicity examination. So it was set to Category 2.
6 Carcinogenicity Not classified - - - - As selenium compounds, it is categorized into D in IRIS (1993) and is categorized into Group 3 in IARC9 (1975). It was out of the Category.
7 Reproductive toxicity Category 2 Warning H361: Suspected of damaging fertility or the unborn child P308+P313: IF exposed or concerned: Get medical advice/attention.
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P405: Store locked up.
P501: Dispose of contents/container to ... 		Although there is no descriptions on general toxicity of parent animals in RTECS (2004) of Priority 2 document, there is description of influence of the postimplantation loss of embryo, the number of child and degree of survival of a child, and it was considered as Category 2.
8 Specific target organ toxicity - Single exposure Category 2 (respiratory system, liver, heart, nervous system) Warning H371: May cause damage to organs (respiratory system, liver, heart, nervous system) P309+P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P405: Store locked up.
P501: Dispose of contents/container to ... 		The substance was classified as Category 2 (respiratory system, liver, heart, nervous system) based on the reports concerning humans in ICSC (J) (1998) and SITTIG (4th, 2002), which are Priority 2 documents.
9 Specific target organ toxicity - Repeated exposure Category 2 (central nervous system, blood, kidney, liver) Warning H373: May cause damage to organs through prolonged or repeated exposure (central nervous system, blood, kidney, liver) P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P314: Get medical advice/attention if you feel unwell.
P501: Dispose of contents/container to ... 		Since there is description of effect on the central nervous systems, blood, the kidney, and liver in human in ICSC(J)(1998), SITTIG (4th, 2002), HSFS (2002) of Priority 2 document, and description of effect on the blood, the kidney, and liver in rats in HSDB (2002) and RTECS (2004) of Priority 2, it was classified into Category 2 (a central nervous systems, blood, kidney, liver).
10 Aspiration hazard Classification not possible - - - - No data available

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment （Acute） Category 1 Warning H400: Very toxic to aquatic life P273: Avoid release to the environment.
P391: Collect spillage.
P501: Dispose of contents/container to ... 		It was classified into Category 1 from 96-hour LC50=0.22 mg/L of fishes (Fathead minnows) (CERI Hazard Data, 2002) .
11 Hazardous to the aquatic environment （Long-term） Category 1 Warning H410: Very toxic to aquatic life with long lasting effects P273: Avoid release to the environment.
P391: Collect spillage.
P501: Dispose of contents/container to ... 		Classified into Category 1, since acute toxicity was Category 1, and it is a metallic compound, behavior in water is unknown., though less bioaccumulative (BCF=12 (existing chemical safety inspections data)).


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：
Reference Manual
Definitions / Abbreviations
Model Label by MHLW

 MHLW Website （in Japanese Only）
Model SDS by MHLW

 MHLW Website （in Japanese Only）

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