Chemical Name:sodium selenite
CAS:10102-18-8
ID: | 1063 |
Classifier: | Inter-ministerial Committee on GHS |
Year Classified: | FY2006 |
Reference Manual: | GHS Classification Manual (10 Feb, 2006) |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
1 | Explosives | Not applicable | - | - | - | - | There are no chemical groups associated with explosive properties present in the molecules. |
2 | Flammable gases (including chemically unstable gases) | Not applicable | - | - | - | - | Solid (GHS definition) |
3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
4 | Oxidizing gases | Not applicable | - | - | - | - | Solid (GHS definition) |
5 | Gases under pressure | Not applicable | - | - | - | - | Solid (GHS definition) |
6 | Flammable liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
7 | Flammable solids | Classification not possible | - | - | - | - | Although ICSC (J) (1998) has the description "it is a flammable under specific conditions", the conditions or examination data are not available. And data is insufficient, it cannot be classified. |
8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | There are no chemical groups associated with explosive or self-reactive properties present in the molecule. |
9 | Pyrophoric liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
10 | Pyrophoric solids | Not classified | - | - | - | - | Even if it contacts the normal temperature air, it does not ignite spontaneously. (Merck (13th, 2001) has the description "It is stabilized in the air".) |
11 | Self-heating substances and mixtures | Classification not possible | - | - | - | - | No data available |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified | - | - | - | - | Stable to water (the water solubility is obtained) |
13 | Oxidizing liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
14 | Oxidizing solids | Classification not possible | - | - | - | - | No data available |
15 | Organic peroxides | Not applicable | - | - | - | - | Inorganic compound |
16 | Corrosive to metals | Classification not possible | - | - | - | - | Test methods applicable to solid substances are not available. |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Category 2 | Danger | H300: Fatal if swallowed |
P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment (see ... on this label). P330: Rinse mouth. P405: Store locked up. P501: Dispose of contents/container to ... |
SPECIES: Rat ENDPOINT: LD50 VALUE: 7mg/kg REFERENCE SOURCE: RTECS(2004) | |
1 | Acute toxicity (Dermal) | Classification not possible | - | - | - | - | No data available |
1 | Acute toxicity (Inhalation: Gases) | Not applicable | - | - | - | - | Solid (GHS definition) |
1 | Acute toxicity (Inhalation: Vapours) | Classification not possible | - | - | - | - | No data available |
1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible | - | - | - | - | No data available |
2 | Skin corrosion/irritation | Category 2 | Warning | H315: Causes skin irritation |
P302+P352: IF ON SKIN: Wash with plenty of soap and water. P332+P313: If skin irritation occurs: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P321: Specific treatment (see ... on this label). P362: Take off contaminated clothing and wash before reuse. |
It was thought that there was stronger skin stimulativeness by the description in the humans (redness, a burn, discoloration, etc.) (ICSC (J) (1998), SITTIG (4th, 2002), and HSFS (2002)), and it was set as Category 2. | |
3 | Serious eye damage/eye irritation | Category 2A | Warning | H319: Causes serious eye irritation |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. |
It is considered that there is strong stimulativeness to the eye in human from the description (redness, pain, damage, etc.) ( ACGIH-TLV (2004), ICSC (J), (1998), SITTIG (4th, 2002), and HSFS (2002)), and it was classified into Category 2A. | |
4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available |
4 | Skin sensitization | Classification not possible | - | - | - | - | Suppose that there is possibility of skin sensitization in the class of EU-Annex I (Access on May 2005). Although there is a case report which suggests human skin sensitization also in HSDB (2002), and there is the description of the human contact dermatitis in ICSC(J)(1998), since data is insufficient, it cannot classify. |
5 | Germ cell mutagenicity | Category 2 | Warning | H341: Suspected of causing genetic defects |
P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ... |
Although there was positive reports (PATTY, 5th, 2001) of a somatic cell in vivo mutagenicity test (mouse bone marrow chromosomal aberration test), there was no report of a productive cell in vivo heredity toxicity examination. So it was set to Category 2. | |
6 | Carcinogenicity | Not classified | - | - | - | - | As selenium compounds, it is categorized into D in IRIS (1993) and is categorized into Group 3 in IARC9 (1975). It was out of the Category. |
7 | Reproductive toxicity | Category 2 | Warning | H361: Suspected of damaging fertility or the unborn child |
P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ... |
Although there is no descriptions on general toxicity of parent animals in RTECS (2004) of Priority 2 document, there is description of influence of the postimplantation loss of embryo, the number of child and degree of survival of a child, and it was considered as Category 2. | |
8 | Specific target organ toxicity - Single exposure | Category 2 (respiratory system, liver, heart, nervous system) | Warning | H371: May cause damage to organs (respiratory system, liver, heart, nervous system) |
P309+P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P405: Store locked up. P501: Dispose of contents/container to ... |
The substance was classified as Category 2 (respiratory system, liver, heart, nervous system) based on the reports concerning humans in ICSC (J) (1998) and SITTIG (4th, 2002), which are Priority 2 documents. | |
9 | Specific target organ toxicity - Repeated exposure | Category 2 (central nervous system, blood, kidney, liver) | Warning | H373: May cause damage to organs through prolonged or repeated exposure (central nervous system, blood, kidney, liver) |
P260: Do not breathe dust/fume/gas/mist/vapours/spray. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ... |
Since there is description of effect on the central nervous systems, blood, the kidney, and liver in human in ICSC(J)(1998), SITTIG (4th, 2002), HSFS (2002) of Priority 2 document, and description of effect on the blood, the kidney, and liver in rats in HSDB (2002) and RTECS (2004) of Priority 2, it was classified into Category 2 (a central nervous systems, blood, kidney, liver). | |
10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Category 1 | Warning | H400: Very toxic to aquatic life |
P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ... |
It was classified into Category 1 from 96-hour LC50=0.22 mg/L of fishes (Fathead minnows) (CERI Hazard Data, 2002) . | |
11 | Hazardous to the aquatic environment (Long-term) | Category 1 | Warning | H410: Very toxic to aquatic life with long lasting effects |
P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ... |
Classified into Category 1, since acute toxicity was Category 1, and it is a metallic compound, behavior in water is unknown., though less bioaccumulative (BCF=12 (existing chemical safety inspections data)). |
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website (in Japanese Only) |
Model SDS by MHLW |
MHLW Website (in Japanese Only) |