GHS Classification Result

Chemical Name:mercury dinitrate
CAS:10045-94-0

Result:
ID: 1057
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual (10 Feb, 2006)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not classified - - - - Not Classified because of UNRTDG No. 1625, Class: 6.1, II and not explosive solely, though the substance contains N-O bonds as chemical groups associated with explosive properties present. (Reactions of the substance with several kinds of compounds such as acetylenes or ethanols lead to explosive products.)
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Solid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Solid (GHS definition)
5 Gases under pressure Not applicable - - - - Solid (GHS definition)
6 Flammable liquids Not applicable - - - - Solid (GHS definition)
7 Flammable solids Not classified - - - - Non-combustible (ICSC (J) (2000))
8 Self-reactive substances and mixtures Not classified - - - - Not classified based on UNRTDG No. 1625, Class: 6.1, PGII
9 Pyrophoric liquids Not applicable - - - - Solid (GHS definition)
10 Pyrophoric solids Not classified - - - - Non-combustible (ICSC (J), 2000)
11 Self-heating substances and mixtures Not classified - - - - Not combustible (ICSC(J) (2000))
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - - Stable to wate (HSDB, 2003)
13 Oxidizing liquids Not applicable - - - - Solid (GHS definition)
14 Oxidizing solids Not classified - - - - Not classified because of UNRTDG No. 1625, Class: 6.1, PGII, though it is a strong oxidizing agent (ICSC(J), 2000; Sax, 11th, 2004).
15 Organic peroxides Not applicable - - - - Inorganic compound
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Category 2 Danger H300: Fatal if swallowed P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P321: Specific treatment (see ... on this label).
P330: Rinse mouth.
P405: Store locked up.
P501: Dispose of contents/container to ...
SPECIES: Rat; ENDPOINT: LD50;VALUE:26mg/kg; REFERENCE SOURCE: RTECS (2005)
1 Acute toxicity (Dermal) Category 2 Danger H310: Fatal in contact with skin P302+P350: IF ON SKIN: Gently wash with plenty of soap and water.
P262: Do not get in eyes, on skin, or on clothing.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P310: Immediately call a POISON CENTER or doctor/physician.
P322: Specific treatment (see ... on this label).
P361: Remove/Take off immediately all contaminated clothing.
P363: Wash contaminated clothing before reuse.
P405: Store locked up.
P501: Dispose of contents/container to ...
It is based on rat dermal LD50= 75mg/kg (RTECS, 2005).
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Solid (GHS definition)
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - - No data available
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - - No data available
2 Skin corrosion/irritation Category 1A-1C Danger H314: Causes severe skin burns and eye damage P301+P330+P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P310: Immediately call a POISON CENTER or doctor/physician.
P321: Specific treatment (see ... on this label).
P363: Wash contaminated clothing before reuse.
P405: Store locked up.
P501: Dispose of contents/container to ...
It was set as Category 1A-1C from the description with the possibility which indicated skin corrosivities (ICSC, 2000) and skin irritation to humans (DFGOT, vol.15, 2001[as inorganic mercury compounds]; HSFS, 1993). [view] When subdivision needs to be performed, it is desirable to be seto as Category 1A from a viewpoint of safety.
3 Serious eye damage/eye irritation Category 1 Danger H318: Causes serious eye damage P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P310: Immediately call a POISON CENTER or doctor/physician.
There is the descripiton of oculo corrosiveness (ICSC, 2000), and it is classified into Category 1 in description of skin corrosivenesses. So it was classified into Category 1.
4 Respiratory sensitization Classification not possible - - - - No data available
4 Skin sensitization Category 1 Warning H317: May cause an allergic skin reaction P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P333+P313: If skin irritation or rash occurs: Get medical advice/attention.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P272: Contaminated work clothing should not be allowed out of the workplace.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P321: Specific treatment (see ... on this label).
P363: Wash contaminated clothing before reuse.
P501: Dispose of contents/container to ...
Metal mercury and inorganic mercury compound (as Hg) were set to Category 1 from description with the possibility which there is skin sensitization (MAK/BAT, 2005; DFGOT, vol.15, 2001), and shows skin sensitization in ICSC (2000).
5 Germ cell mutagenicity Category 2 Warning H341: Suspected of causing genetic defects P308+P313: IF exposed or concerned: Get medical advice/attention.
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P405: Store locked up.
P501: Dispose of contents/container to ...
In ATSDR (1999), since it estimated that mercury and mercury compounds induced chromosomal abnormality to the animal somatic cell in an in vivo, they were set to Category 3.
6 Carcinogenicity Not classified - - - - As inorganic mercury compounds, it was out of the Category. Since it is classified into IARC Group 3 (IARC, 58, 1993) and ACGIH A4 (ACGIH-TLV, 2004).
7 Reproductive toxicity Category 2 Warning H361: Suspected of damaging fertility or the unborn child P308+P313: IF exposed or concerned: Get medical advice/attention.
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P405: Store locked up.
P501: Dispose of contents/container to ...
Since the effect on generating (California EPA, Proposition 65 List of Chemicals, 2005) and reproductive (ACGIH-TLV, 2004) was indicated as mercury and mercury compounds or inorganic mercuries, it was considered as Category 2.
8 Specific target organ toxicity - Single exposure Category 1 (kidney), Category 2 (respiratory system) Danger
Warning
H370: Causes damage to organs (kidney)
H371: May cause damage to organs (respiratory system)
P307+P311: IF exposed: Call a POISON CENTER or doctor/physician.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P309+P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician.
The substance was classified as Category 1 (kidneys) and Category 2 (respiratory organs) based on the reports concerning humans in Priority 1 documents that the target organs of the substance in the inorganic mercury compound are the kidneys (DFGOT, vol.15, 2001), and on the reports of the effects on the kidneys and airways corrosivity or respiratory organ irritant properties in Priority 2 documents (ICSC, 2000; HSFS, 1993; SITTIG, 4th, 2002).
9 Specific target organ toxicity - Repeated exposure Category 1 (central nervous system, kidney) Danger H372: Cause damage to organs through prolonged or repeated exposure (central nervous system, kidney) P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P314: Get medical advice/attention if you feel unwell.
P501: Dispose of contents/container to ...
Since in Priority 1 document, the effect on the central nervous systems and the kidneyto humans by inorganic mercury compounds was described (ACGIH-TLV, 2004;EHC, 118, 1991) , and the effect on the nervous system and the kidney by the product was indicated in Priority 2 document (ICSC, 2000;SITTIG, 4th, 2002), it was classified into Category 1 (a central nervous systems, the kidney).
10 Aspiration hazard Classification not possible - - - - No data available

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Category 1 Warning H400: Very toxic to aquatic life P273: Avoid release to the environment.
P391: Collect spillage.
P501: Dispose of contents/container to ...
It was classified into Category 1 from 96-hour LC50=33microg/L(mercury (II) nitrate concentration equivalent: 53microg/L) of fishes (Rainbow trout) (EHC86, 1989).
11 Hazardous to the aquatic environment (Long-term) Category 1 Warning H410: Very toxic to aquatic life with long lasting effects P273: Avoid release to the environment.
P391: Collect spillage.
P501: Dispose of contents/container to ...
Classified into Category 1, since acute toxicity was Category 1, and it is a metallic compound, behavior in water and bioaccumulative potential are unknown.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model Label by MHLW

MHLW Website (in Japanese Only)

Model SDS by MHLW

MHLW Website (in Japanese Only)


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