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GHS Classification Result

Chemical Name：Methyl cyclohexane
CAS：108-87-2

Result：


ID:	977
Classifier:	Inter-ministerial Committee on GHS
Year Classified:	FY2006
Reference Manual:	GHS Classification Manual （10 Feb, 2006）

PHYSICAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Explosives	Not applicable	-	-	-	-	There are no chemical groups associated with explosive properties present in the molecules.
2	Flammable gases （including chemically unstable gases）	Not applicable	-	-	-	-	Liquid (GHS definition)
3	Aerosols	Not applicable	-	-	-	-	Not aerosol products
4	Oxidizing gases	Not applicable	-	-	-	-	Liquid (GHS definition)
5	Gases under pressure	Not applicable	-	-	-	-	Liquid (GHS definition)
6	Flammable liquids	Category 2		Danger	H225: Highly flammable liquid and vapour	P303+P361+P353: IF ON SKIN （or hair）: Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P370+P378: In case of fire: Use ... for extinction. P403+P235: Store in a well-ventilated place. Keep cool. P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P233: Keep container tightly closed. P240: Ground/bond container and receiving equipment. P241: Use explosion-proof electrical/ventilating/lighting/.../equipment. P242: Use only non-sparking tools. P243: Take precautionary measures against static discharge. P280: Wear protective gloves/protective clothing/eye protection/face protection. P501: Dispose of contents/container to ...	UNRTDG Class: 3; PG II
7	Flammable solids	Not applicable	-	-	-	-	Liquid (GHS definition)
8	Self-reactive substances and mixtures	Not applicable	-	-	-	-	There are no chemical groups associated with explosive or self-reactive properties present in the molecule.
9	Pyrophoric liquids	Not classified	-	-	-	-	Not ignite spontaneously on coming into contact with air at normal temperatures
10	Pyrophoric solids	Not applicable	-	-	-	-	Liquid (GHS definition)
11	Self-heating substances and mixtures	Classification not possible	-	-	-	-	Test methods applicable to liquid substances are not available
12	Substances and mixtures which, in contact with water, emit flammable gases	Not applicable	-	-	-	-	The chemical structure of the substance does not contain metals or metaloids(B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13	Oxidizing liquids	Not applicable	-	-	-	-	Organic compounds containing no oxygen, fluorine and chlorine.
14	Oxidizing solids	Not applicable	-	-	-	-	Liquid (GHS definition)
15	Organic peroxides	Not applicable	-	-	-	-	Containing no -0-0- structure
16	Corrosive to metals	Not classified	-	-	-	-	Steel and aluminum can be used as a container.

HEALTH HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Acute toxicity （Oral）	Category 4		Warning	H302: Harmful if swallowed	P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P330: Rinse mouth. P501: Dispose of contents/container to ...	Rabbit LDLo: 4000 - 4500mg/kg (PATTY 4th, 1994), rat LD50 value: >3200mg/kg (RTECS, 2005) and mouse LD50 value: 1200mg /kg (RTECS, 2005). Based on the lowest LD50 value of the mouse data, it was classified to category 4.
1	Acute toxicity （Dermal）	Not classified	-	-	-	-	Based on rabbit LD50 value: >86700mg/kg (PATTY 4th, 1994), it was set as the outside of Category.
1	Acute toxicity （Inhalation: Gases）	Not applicable	-	-	-	-	Liquid (GHS definition)
1	Acute toxicity （Inhalation: Vapours）	Not classified	-	-	-	-	There is description of LC50 (2 hours) value: 36.9mg/L (4-hour equivalent: 26.1mg/L). But death is not observed with 7500 - 10000ppm on mouse but observed with 2-hour exposure to 10000 - 12,500ppm (4-hour equivalent assuming 10000ppm: 28.399mg/L) (ACGIH (7th, 2001) and Industrial Hygiene Society advice state). It was judged that there is no death observed below 28.399mg/L (equivalent of 7082ppm), and it was classified as out of Category by the ppm concentration standard.
1	Acute toxicity （Inhalation: Dusts and mists）	Classification not possible	-	-	-	-	No data available
2	Skin corrosion/irritation	Category 3	-	Warning	H316: Causes mild skin irritation	P332+P313: If skin irritation occurs: Get medical advice/attention.	It was set as Category 3 from description that the skin was stimulated without concrete case report (ICSC (J) (1997), HSDB (2005), and SITTIG (4th, 2002)), and description that mild irritating was acknowledged in the test applied to the skin of the rabbit although it was exposure for 24 hours (RTECS (2005)).
3	Serious eye damage/eye irritation	Category 2B	-	Warning	H320: Causes eye irritation	P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P264: Wash ... thoroughly after handling.	Based on the description in RTECS (2005) that mild irritant property was acknowledged in the test applied to the eyes of the rabbits, and on the descriptions in ICSC (J) (1997) and SITTIG (4th, 2002) that it stimulated the eyes, we categorized it as Category 2B although there were no concrete case reports.
4	Respiratory sensitization	Classification not possible	-	-	-	-	No data available
4	Skin sensitization	Classification not possible	-	-	-	-	No data available
5	Germ cell mutagenicity	Classification not possible	-	-	-	-	No data available
6	Carcinogenicity	Classification not possible	-	-	-	-	No data available
7	Reproductive toxicity	Classification not possible	-	-	-	-	No data available
8	Specific target organ toxicity - Single exposure	Category 3 （Narcotic effects）		Warning	H336: May cause drowsiness or dizziness (narcotic effects)	P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P405: Store locked up. P501: Dispose of contents/container to ...	Because of descriptions in ACGIH (7th, 2001) and Japan Society for Occupational Health recommendation (1993) referring to confirmation of abdominal positions in inhalation exposure tests with mice, and of a description in ACGIH (7th, 2001) referring to that anesthetic actions were confirmed in an inhalation exposure test using rabbits, and of descriptions in ICSC (J) (1997), HSDB (2005), HSFS (2002), and SITTIG (4th, 2002) referring to that central nervous systems were affected. So it was judged that there were anesthetic actions, and determined as Category 3 (anesthetic actions).
9	Specific target organ toxicity - Repeated exposure	Classification not possible	-	-	-	-	Classification not possible due to lack of data
10	Aspiration hazard	Category 1		Danger	H304: May be fatal if swallowed and enters airways	P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P331: Do NOT induce vomiting. P405: Store locked up. P501: Dispose of contents/container to ...	Since it is a hydrocarbon and the dynmic viscosity is about 0.95 mm2/s at 20 degrees C ( viscosity/density = 0.732 (mPas)/0.7694 (g/cm3)), and the dynamic viscosity at 40 degrees C is considered to be less than 20.5 mm2/s, we classified it as Category 1.

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
11	Hazardous to the aquatic environment （Acute）	Category 2	-	-	H401: Toxic to aquatic life	P273: Avoid release to the environment. P501: Dispose of contents/container to ...	It was classified into Category 2 from 96-hour LC50=3300microg/L of Crustacea (Brown shrimp) (AQUIRE, 2003).
11	Hazardous to the aquatic environment （Long-term）	Category 2		-	H411: Toxic to aquatic life with long lasting effects	P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ...	Classified into Category 2, since acute toxicity was Category 2 and not rapidly degrading (BOD: 0% (existing chemical safety inspections data)), though less bio-accumulative (BCF=321 (existing chemical safety inspections data)).

NOTE:

* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：

Reference Manual
Definitions / Abbreviations
Model SDS by MHLW	MHLW Website （in Japanese Only）