NITE - Chemical Management Field

GHS Classification Result

Chemical Name：Lithium hydroxide monohydrate
CAS：1310-66-3

Result：


ID:	813
Classifier:	Inter-ministerial Committee on GHS
Year Classified:	FY2006
Reference Manual:	GHS Classification Manual （10 Feb, 2006）

PHYSICAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Explosives	Not applicable	-	-	-	-	There are no chemical groups associated with explosive properties present in the molecules.
2	Flammable gases （including chemically unstable gases）	Not applicable	-	-	-	-	Solid (GHS definition)
3	Aerosols	Not applicable	-	-	-	-	Not aerosol products
4	Oxidizing gases	Not applicable	-	-	-	-	Solid (GHS definition)
5	Gases under pressure	Not applicable	-	-	-	-	Solid (GHS definition)
6	Flammable liquids	Not applicable	-	-	-	-	Solid (GHS definition)
7	Flammable solids	Not classified	-	-	-	-	Non-combustible substance
8	Self-reactive substances and mixtures	Not applicable	-	-	-	-	There are no chemical groups associated with explosive or self-reactive properties present in the molecule.
9	Pyrophoric liquids	Not applicable	-	-	-	-	Solid (GHS definition)
10	Pyrophoric solids	Not classified	-	-	-	-	Non-combustible
11	Self-heating substances and mixtures	Not classified	-	-	-	-	Non-flammable materials. Although it absorbs moisture and generates heat from air, it does not result in ignition.
12	Substances and mixtures which, in contact with water, emit flammable gases	Not classified	-	-	-	-	If water is contacted, it will react violently, but what is generated is heat of solution and flammable gases does not occur. (GESTIS (2006))
13	Oxidizing liquids	Not applicable	-	-	-	-	Solid (GHS definition)
14	Oxidizing solids	Not classified	-	-	-	-	Although it contains oxygen, lithium is a stable metal in monovalence, and lithium hydroxide does not give oxygen to other substances generally.
15	Organic peroxides	Not applicable	-	-	-	-	Inorganic substance
16	Corrosive to metals	Classification not possible	-	-	-	-	Hommmel has a description that "Since aluminum and zinc receive corrosive effects, it is not suitable as a container. The corrosive effects becomes strong remarkably, when moisture or waters exists. Steels, stainless steels, glass, ceramics and many synthetics are durable as a container. " However, the corrosion velocity data against aluminum is not found out and it cannot be classified. Category 1 is presumed.

HEALTH HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Acute toxicity （Oral）	Category 3		Danger	H301: Toxic if swallowed	P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment （see ... on this label）. P330: Rinse mouth. P405: Store locked up. P501: Dispose of contents/container to ...	Category 3 based on SPECIES: Rat; ENDPOINT: LD50;:210mg/kg; REFERENCE SOURCE: RTECS (2000)
1	Acute toxicity （Dermal）	Classification not possible	-	-	-	-	There is no data, so it cannot be classified. It is a strong corrosive substance and an experiment of dermal absorption exposure cannot be performed.
1	Acute toxicity （Inhalation: Gases）	Not applicable	-	-	-	-	Solid (GHS definition)
1	Acute toxicity （Inhalation: Vapours）	Classification not possible	-	-	-	-	It is a nonvolarility solid and inhalation exposure test with vapor cannot be done.
1	Acute toxicity （Inhalation: Dusts and mists）	Category 3		Danger	H331: Toxic if inhaled	P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P311: Call a POISON CENTER or doctor/physician. P321: Specific treatment （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ...	Category 3 because of SPECIES: Rat; ENDPOINT: LC50; VALUE: 0.96mg/L/4H
2	Skin corrosion/irritation	Category 1B		Danger	H314: Causes severe skin burns and eye damage	P301+P330+P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353: IF ON SKIN （or hair）: Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P310: Immediately call a POISON CENTER or doctor/physician. P321: Specific treatment （see ... on this label）. P363: Wash contaminated clothing before reuse. P405: Store locked up. P501: Dispose of contents/container to ...	The data of the animal examination was not able to be found out. But description of each collections of hazard data, such as ICSC (1998), HSFS (2004), and GESTIS (2006), had expression of "causing a burn on the skin,", and it was set as Category 1. It is set as a class 8 and PG II in the U.N. dangerous object shipping regulations. It is set to Category1B for the purpose of transportation.
3	Serious eye damage/eye irritation	Category 1		Danger	H318: Causes serious eye damage	P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P280: Wear protective gloves/protective clothing/eye protection/face protection. P310: Immediately call a POISON CENTER or doctor/physician.	Although the animal data was not able to be found out, collections of hazard data (such as ICSC (1998) and GESTIS (2006)), have description "severe burns is caused." Since it was also set as Category 1 in skin corrosivity, it was set as "Category 1".
4	Respiratory sensitization	Classification not possible	-	-	-	-	There is no information and we could not classify it. It is alkaline metal hydroxide and it is converted into salt in the body. We think that it has no any sensitizing property.
4	Skin sensitization	Classification not possible	-	-	-	-	There is no information and we could not classify it. It is alkaline metal hydroxide and it is converted into salt in the body. We think that it has no any sensitizing property.
5	Germ cell mutagenicity	Classification not possible	-	-	-	-	Classification not possible due to lack of data
6	Carcinogenicity	Classification not possible	-	-	-	-	Classification not possible due to lack of data
7	Reproductive toxicity	Classification not possible	-	-	-	-	Classification not possible due to lack of data
8	Specific target organ toxicity - Single exposure	Category 1 (Inhalation: respiratory)		Danger	H370: Causes damage to organs (Inhalation: respiratory)	P307+P311: IF exposed: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ...	ICSC (1998), HSFS (2004), etc. have descriptions about respiratory irritation and lung edema. Therefore we adopted "inhalation, respiratory system". Although they are the priority 2 literature, we classified it into "Category 1" because they have descriptions that the characteristic within the guidance value to Category 1 was found in animal experiments.
9	Specific target organ toxicity - Repeated exposure	Category 1 (Inhalation: respiratory), Category 2 (Oral: liver, hematopoietic system)		Danger Warning	H372: Cause damage to organs through prolonged or repeated exposure (Inhalation: respiratory) H373: May cause damage to organs through prolonged or repeated exposure (Oral: liver, hematopoietic system)	P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ...	In the animal experiment, the effects on the respiratory system was seen within the guidance value of Category 1 (RTECS (2000)). Moreover, since the bronchitis accompanied by a cough, inflammation, and respiratory distress was indicated in HSFS (2004), it was classified into "Category 1 (inhalation and respiratory system)." Moreover, the effects on liver and the hematopoietic systems in oral administration at very lower than the guidance value of Category 1 are described (RTECS (2000)), but it adopted as "Category 2 (oral, liver, hematopoietic systems)" since there was doubt of error in inputting the unit of RTECS.
10	Aspiration hazard	Classification not possible	-	-	-	-	No data available

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
11	Hazardous to the aquatic environment （Acute）	Classification not possible	-	-	-	-	No data available
11	Hazardous to the aquatic environment （Long-term）	Classification not possible	-	-	-	-	No data available.

NOTE:

* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：

Reference Manual
Definitions / Abbreviations
Model SDS by MHLW	MHLW Website （in Japanese Only）