Chemical Name:oxalonitrile
CAS:460-19-5
ID: | 781 |
Classifier: | Inter-ministerial Committee on GHS |
Year Classified: | FY2006 |
Reference Manual: | GHS Classification Manual (10 Feb, 2006) |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
1 | Explosives | Not applicable | - | - | - | - | Gas (GHS definition) |
2 | Flammable gases (including chemically unstable gases) | Category 1 | Danger | H220: Extremely flammable gas |
P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P377: Leaking gas fire: Do not extinguish, unless leak can be stopped safely. P381: Eliminate all ignition sources if safe to do so. P403: Store in a well-ventilated place. |
UNRTDG No.1026, Class: 2.3 (2.1) | |
3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
4 | Oxidizing gases | Not classified | - | - | - | - | UNRTDG No.1026, Class: 2.3 and 2.1 |
5 | Gases under pressure | Liquefied gas | Warning | H280: Contains gas under pressure; may explode if heated | P410+P403: Protect from sunlight. Store in a well-ventilated place. | Liquefied gas because of "the steam pressure: 11.5 atm at 50degC"(GESTIS, 2006) which is >3 atm, and "the critical temp: 128.3degC" (HSDB, 2005) which is >65degC | |
6 | Flammable liquids | Not applicable | - | - | - | - | Gas (GHS definition) |
7 | Flammable solids | Not applicable | - | - | - | - | Gas (GHS definition) |
8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | Gas (GHS definition) |
9 | Pyrophoric liquids | Not applicable | - | - | - | - | Gas (GHS definition) |
10 | Pyrophoric solids | Not applicable | - | - | - | - | Gas (GHS definition) |
11 | Self-heating substances and mixtures | Not applicable | - | - | - | - | Gas (GHS definition) |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | Gas (GHS definition) |
13 | Oxidizing liquids | Not applicable | - | - | - | - | Gas (GHS definition) |
14 | Oxidizing solids | Not applicable | - | - | - | - | Gas (GHS definition) |
15 | Organic peroxides | Not applicable | - | - | - | - | Gas (GHS definition) |
16 | Corrosive to metals | Classification not possible | - | - | - | - | Test methods applicable to gas substances are not available |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Classification not possible | - | - | - | - | No data available |
1 | Acute toxicity (Dermal) | Classification not possible | - | - | - | - | No data available |
1 | Acute toxicity (Inhalation: Gases) | Category 2 | Danger | H330: Fatal if inhaled |
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P284: Wear respiratory protection. P310: Immediately call a POISON CENTER or doctor/physician. P320: Specific treatment is urgent (see ... on this label). P405: Store locked up. P501: Dispose of contents/container to ... |
It was considered as Category 2 based on rat inhalation exposures LC50= 175ppm (4-hour equivalent) (Patty (5th, 2001)). | |
1 | Acute toxicity (Inhalation: Vapours) | Not applicable | - | - | - | - | Gas (GHS definition) |
1 | Acute toxicity (Inhalation: Dusts and mists) | Not applicable | - | - | - | - | Gas (GHS definition) |
2 | Skin corrosion/irritation | Classification not possible | - | - | - | - | Lack of data. [Notes] Frostbite is reported on humans with contact with solution (ICSC(2001); HSFS (2000)). |
3 | Serious eye damage/eye irritation | Category 2A-2B | Warning | H319: Causes serious eye irritation |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. |
Based on that eye irritations are reported in humans (ATSDR(2004);ACGIH (2001), it was set as Category 2A-2B. | |
4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available |
4 | Skin sensitization | Classification not possible | - | - | - | - | No data available |
5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | No data available |
6 | Carcinogenicity | Classification not possible | - | - | - | - | No data available |
7 | Reproductive toxicity | Classification not possible | - | - | - | - | No data available |
8 | Specific target organ toxicity - Single exposure | Category 1 (central nervous system), Category 3 (respiratory tract irritation) |
Danger Warning |
H370: Causes damage to organs (central nervous system) H335: May cause respiratory irritation (respiratory tract irritation) |
P307+P311: IF exposed: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment (see ... on this label). P405: Store locked up. P501: Dispose of contents/container to ... P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P312: Call a POISON CENTER or doctor/physician if you feel unwell. |
In humans, affected to the central nervous systems (respiratory failure and collapses) (ICSC (2001)). Moreover, central nervous systems influences, such as hyperkinesis, panic, cooperativeness lack, thrill, a lethargica, etc. (ATSDR (2004)) being admitted at 175 ppm (4-hour equivalent) in a rat. So it is classified into Category 1 (central nervous systems). Furthermore, based on the human nose and the respiratory irritation is reported (ATSDR(2004); ICSC (2001)), it is classified into Category 3 (respiratory irritation). | |
9 | Specific target organ toxicity - Repeated exposure | Category 2 (nervous system) | Warning | H373: May cause damage to organs through prolonged or repeated exposure (nervous system) |
P260: Do not breathe dust/fume/gas/mist/vapours/spray. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ... |
Based on that effect on the nervous system on the humans is reported (HSFS(2000);SITTING (2002)), it was classified into Category 2. However, the animal study data is not endorsing this. | |
10 | Aspiration hazard | Not applicable | - | - | - | - | Gas (GHS definition) |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Classification not possible | - | - | - | - | No data available |
11 | Hazardous to the aquatic environment (Long-term) | Classification not possible | - | - | - | - | No data available. |
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference Manual |
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Definitions / Abbreviations |
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Model SDS by MHLW |
MHLW Website (in Japanese Only) |