GHS Classification Result
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：1,3-Cyclopentadiene
CAS：542-92-7
Result：
| ID: | 769 |
| Classifier: | Inter-ministerial Committee on GHS |
| Year Classified: | FY2006 |
| Reference Manual: | GHS Classification Manual （10 Feb, 2006） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | Classification not possible | - | - | - | - | Classification not possible due to lack of data, though the substance contains unsaturated C=C bonds as chemical groups associated with explosive properties present. |
| 2 | Flammable gases （including chemically unstable gases） | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
| 4 | Oxidizing gases | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 5 | Gases under pressure | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 6 | Flammable liquids | Category 2 |
|
Danger | H225: Highly flammable liquid and vapour |
P303+P361+P353: IF ON SKIN （or hair）: Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P370+P378: In case of fire: Use ... for extinction. P403+P235: Store in a well-ventilated place. Keep cool. P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P233: Keep container tightly closed. P240: Ground/bond container and receiving equipment. P241: Use explosion-proof electrical/ventilating/lighting/.../equipment. P242: Use only non-sparking tools. P243: Take precautionary measures against static discharge. P280: Wear protective gloves/protective clothing/eye protection/face protection. P501: Dispose of contents/container to ... |
Although there are deviations in the flash point data, ICSC (1996) data is 25 degC with Open Cup, and other data (Chapman (CD-ROM ver.14.1 2006) and Gangolli (2nd, 1999)) were less than 23 degC (unknown measurements). And it was classified as Category 2 (GHS acceptance criteria: flash point being less than 23 degC, and initial boiling point being more than 35 degC) considering its boiling point: 41.5 - 42.0 degC. |
| 7 | Flammable solids | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 8 | Self-reactive substances and mixtures | Classification not possible | - | - | - | - | Classification not possible due to lack of data, though the substance contains C=C bonds as chemical groups with explosive or self-reactive properties present |
| 9 | Pyrophoric liquids | Not classified | - | - | - | - | The ignition points is 640 degC (ICSC (1996), an organic compounds dictionary (1985), HSDB (2005)) |
| 10 | Pyrophoric solids | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 11 | Self-heating substances and mixtures | Classification not possible | - | - | - | - | Test methods applicable to liquid substances are not available |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | The chemical structure of the substance does not contain metals or metaloids(B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At). |
| 13 | Oxidizing liquids | Not applicable | - | - | - | - | Organic compounds containing no oxygen, fluorine and chlorine. |
| 14 | Oxidizing solids | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 15 | Organic peroxides | Not applicable | - | - | - | - | Organic compounds containing no -0-0- structure |
| 16 | Corrosive to metals | Classification not possible | - | - | - | - | Boiling point: <55degC (41.5-42degC). Test methods applicable to gas substance are not available. |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Category 3 |
|
Danger | H301: Toxic if swallowed |
P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment （see ... on this label）. P330: Rinse mouth. P405: Store locked up. P501: Dispose of contents/container to ... |
Category 3 based on SPECIES: Rat; ENDPOINT: LD50; VALUE: 113 mg/kg; REFERENCE SOURCE: RTECS(2004) |
| 1 | Acute toxicity （Dermal） | Category 3 |
|
Danger | H311: Toxic in contact with skin |
P302+P352: IF ON SKIN: Wash with plenty of soap and water. P280: Wear protective gloves/protective clothing/eye protection/face protection. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P322: Specific treatment （see ... on this label）. P361: Remove/Take off immediately all contaminated clothing. P363: Wash contaminated clothing before reuse. P405: Store locked up. P501: Dispose of contents/container to ... |
It was set as Category 3 from rabbit dermal LD50 = 430mg/kg (RTECS (2004)). |
| 1 | Acute toxicity （Inhalation: Gases） | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 1 | Acute toxicity （Inhalation: Vapours） | Category 4 |
|
Warning | H332: Harmful if inhaled |
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P312: Call a POISON CENTER or doctor/physician if you feel unwell. |
Based on LC50 (4hr) = 19mg/L which is a converted value for 4 hours of rat inhalation LC50 (1hr) = 39mg/L, it was classified as Category 4. In addition, the saturated concentration of this product is 5.7*10~5ppm (equivalent value: 1550mg/L), and it is presumed that this experiment was conducted with steam. |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Classification not possible | - | - | - | - | No data available |
| 2 | Skin corrosion/irritation | Classification not possible | - | - | - | - | Insufficient data available |
| 3 | Serious eye damage/eye irritation | Category 2A-2B |
|
Warning | H319: Causes serious eye irritation |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. |
Since there is the description that this product stimulates the eyes (PATTY(5th, 2001); ICSC(J) (1996); SITTIG(4th, 2002); HSDB(2005); HSFS (1999)), it was set as Category 2A-2B. [Indications] in the case that subdividing are necessary, it is more desirable to make it Category 2A from the viewpoint of safety. |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data |
| 4 | Skin sensitization | Classification not possible | - | - | - | - | Since there is no specific data for the description about this substance that skin allergy and contact dermatitis are caused (PATTY(5th, 2001);SITTIG(4th, 2002);HSFS (1999)) , it cannot be classified due to insufficiency of data. |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | No data available |
| 6 | Carcinogenicity | Classification not possible | - | - | - | - | No data available |
| 7 | Reproductive toxicity | Classification not possible | - | - | - | - | No data available |
| 8 | Specific target organ toxicity - Single exposure | Category 3 （Respiratory tract irritation） |
|
Warning | H335: May cause respiratory irritation (respiratory tract irritation) |
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P405: Store locked up. P501: Dispose of contents/container to ... |
Since this substance had description that mucosa and an respiratory irritation (PATTY (5th, 2001); ICSC(J) (1996); SITTIG (4th, 2002)), it is classified into Category 3 (respiratory irritation). |
| 9 | Specific target organ toxicity - Repeated exposure | Category 2 (liver, kidney) |
|
Warning | H373: May cause damage to organs through prolonged or repeated exposure (liver, kidney) |
P260: Do not breathe dust/fume/gas/mist/vapours/spray. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ... |
The effect on liver (slight cloudy swelling near lobule) and the kidney (opacity vacuolar degeneration of a kidney nephric tubule epithelium) was observed as a result of the inhalation experiment to the rat in the document of Priority 1(ACGIH(7th, 2001)-ATTY (5th, 2001)). If the conditions of this experiment(for 500 ppm / 7 h/day, and 53 35 times / days) is coverted to compare with a guidance value (mg/L/6 h/day, 90 days), average concentration dose serves as 0.45 mg/L/6 h/day, and it is in the range of Category 2 in a guidance value. (In addition, the concentration of saturated solution of the this product was about 574000 ppm, and since it was presumed that the inhalation experiments by 500 ppm was conducted with steam.), it was classidfied into Category 2 (liver, kidney). |
| 10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Classification not possible | - | - | - | - | No data available |
| 11 | Hazardous to the aquatic environment （Long-term） | Classification not possible | - | - | - | - | No data available. |
NOTE:
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* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
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Reference Manual |
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Definitions / Abbreviations |
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Model SDS by MHLW |
MHLW Website （in Japanese Only） |