GHS Classification Result

Chemical Name:3-Pentanone
CAS:96-22-0

Result:
ID: 760
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual (10 Feb, 2006)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecules.
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Liquid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Liquid (GHS definition)
5 Gases under pressure Not applicable - - - - Liquid (GHS definition)
6 Flammable liquids Category 2 Danger H225: Highly flammable liquid and vapour P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P370+P378: In case of fire: Use ... for extinction.
P403+P235: Store in a well-ventilated place. Keep cool.
P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P233: Keep container tightly closed.
P240: Ground/bond container and receiving equipment.
P241: Use explosion-proof electrical/ventilating/lighting/.../equipment.
P242: Use only non-sparking tools.
P243: Take precautionary measures against static discharge.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P501: Dispose of contents/container to ...
Flash point: <23degC, Initial boiling point: >35degC
7 Flammable solids Not applicable - - - - Liquid (GHS definition)
8 Self-reactive substances and mixtures Not applicable - - - - There are no chemical groups associated with explosive or self-reactive properties present in the molecule.
9 Pyrophoric liquids Not classified - - - - It is the liquid with ignition points of 452 degC (ICSC (1996)) and it does not ignite in room temperatures.
10 Pyrophoric solids Not applicable - - - - Liquid (GHS definition)
11 Self-heating substances and mixtures Classification not possible - - - - Test methods applicable to liquid substances are not available
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable - - - - The chemical structure of the substance does not contain metals or metaloids(B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13 Oxidizing liquids Not applicable - - - - Organic compounds containing oxygen (but not chlorine and fluorine) chemically bonded only to carbon (but not to other elements).
14 Oxidizing solids Not applicable - - - - Liquid (GHS definition)
15 Organic peroxides Not applicable - - - - Organic compounds containing no -0-0- structure
16 Corrosive to metals Classification not possible - - - - No data available

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Category 5 - Warning H303: May be harmful if swallowed P312: Call a POISON CENTER or doctor/physician if you feel unwell. SPECIES: Rat ENDPOINT: LD50 VALUE: 2140 mg/kg REFERENCE SOURCE: ACGIH (2001)
1 Acute toxicity (Dermal) Category 5 - Warning H313: May be harmful in contact with skin P312: Call a POISON CENTER or doctor/physician if you feel unwell. It was set as Category 5 from rat LD50 : 2100mg/kg (RTECS (2004)).
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Liquid (GHS definition)
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - - Since data is insufficient, it cannot be classified. (Since there is data that 4/6-animal death with 8000ppm/4H exposure in rat test, it is presumed to be Category 5)
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - - No data available
2 Skin corrosion/irritation Category 3 - Warning H316: Causes mild skin irritation P332+P313: If skin irritation occurs: Get medical advice/attention. Based on the evaluation of Mild in the examination on rabbits (ACGIH (2001)), it was classified as Category 3. .
3 Serious eye damage/eye irritation Category 2A Warning H319: Causes serious eye irritation P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
It was set as Category 2A from the moderate by the examination of the rabbit (ACGIH (2001)).
4 Respiratory sensitization Classification not possible - - - - As there is no data, it cannot be classified.
4 Skin sensitization Not classified - - - - Based on the negative result of a test in humans (IUCLI (2000)), it was put outside of Category.
5 Germ cell mutagenicity Classification not possible - - - - Classification not possible due to lack of data
6 Carcinogenicity Classification not possible - - - - Classification not possible due to lack of data and reports
7 Reproductive toxicity Classification not possible - - - - Although there is a report of having no influence in the mouse reproduction studies (IUCLID (2000)), it cannot be classified due to insufficient data.
8 Specific target organ toxicity - Single exposure Category 1 (central nervous system), Category 3 (narcotic effects, respiratory tract irritation) Danger
Warning
H370: Causes damage to organs (central nervous system)
H336: May cause drowsiness or dizziness (narcotic effects, respiratory tract irritation)
H335: May cause respiratory irritation (narcotic effects, respiratory tract irritation)
P307+P311: IF exposed: Call a POISON CENTER or doctor/physician.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P271: Use only outdoors or in a well-ventilated area.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
By inhalation exposure, a coma (PATTY (5th, 2001)), a coma, giddiness, headache, malfunction, and depression of the central nervous system are caused (HSDB (2005)), si it was set as category 1 (central nervous system)), and it segmented into Category 3 (anaesthetic). And from the statement of respiratory irritation (ICSC (1996), HSDB (2005), ACGIH (2001)), it was set as category 3 (respiratory irritation).
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - There is only a report of the drinking water administration examination outside the guidance value of Category 2. It cannot be classified due to insufficient data.
10 Aspiration hazard Category 2 Warning H305: May be harmful if swallowed and enters airways P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P331: Do NOT induce vomiting.
P405: Store locked up.
P501: Dispose of contents/container to ...
We have a statement that the aspiration into the lungs may occure the chemical pneumonia (HSDB (2005)), and we classified it as Category 2 as it being ketone with the carbon numbers 5.

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Not classified - - - - It carried out the outside of Category from 48-hour EC50>500mg/L of Crustacea (Daphnia magna) (IUCLID, 2000).
11 Hazardous to the aquatic environment (Long-term) Not classified - - - - Since not water-insoluble (aqueous solubility =48100 mg/L (PHYSPROP Database, 2005)) and acute toxicity is low.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model SDS by MHLW

MHLW Website (in Japanese Only)


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