Chemical Name:Cyanamide
CAS:420-04-2
ID: | 749 |
Classifier: | Inter-ministerial Committee on GHS |
Year Classified: | FY2006 |
Reference Manual: | GHS Classification Manual (10 Feb, 2006) |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
1 | Explosives | Not applicable | - | - | - | - | There are no chemical groups associated with explosive properties present in the molecules. |
2 | Flammable gases (including chemically unstable gases) | Not applicable | - | - | - | - | Liquid (GHS definition) |
3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
4 | Oxidizing gases | Not applicable | - | - | - | - | Liquid (GHS definition) |
5 | Gases under pressure | Not applicable | - | - | - | - | Liquid (GHS definition) |
6 | Flammable liquids | Not classified | - | - | - | - | Flash point of liquid articles: none |
7 | Flammable solids | Not applicable | - | - | - | - | Liquid (GHS definition) |
8 | Self-reactive substances and mixtures | Classification not possible | - | - | - | - | Classification not possible due to lack of data on liquid articles, though the substance contains aminonitrile groups as chemical groups with self-reactive properties present. |
9 | Pyrophoric liquids | Not classified | - | - | - | - | A liquid product is not flammable nor ignitability. |
10 | Pyrophoric solids | Not applicable | - | - | - | - | Liquid (GHS definition) |
11 | Self-heating substances and mixtures | Classification not possible | - | - | - | - | Since the liquid (liquid product) examining method hass not been established, it cannot be classified. |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | The chemical structure of the substance does not contain metals or metaloids(B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At). |
13 | Oxidizing liquids | Not applicable | - | - | - | - | Organic compounds containing no oxygen, fluorine and chlorine. |
14 | Oxidizing solids | Not applicable | - | - | - | - | Liquid (GHS definition) |
15 | Organic peroxides | Not applicable | - | - | - | - | Inorganic substance |
16 | Corrosive to metals | Classification not possible | - | - | - | - | No data available on corrosion to metals |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Category 3 (Active ingredient) | Danger | H301: Toxic if swallowed (Active ingredient) |
P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment (see ... on this label). P330: Rinse mouth. P405: Store locked up. P501: Dispose of contents/container to ... |
It is in Category 5, because it is over LD50= 2415mg/kg (Agricultural-Chemicals abstracts (2002)) in the male rat examination, and this is over 2000mg/kg (Category 4). Moreover, it is thought that a pure forms (active ingredient) is in Category 3 by being estimated from this value. | |
1 | Acute toxicity (Dermal) | Classification not possible (Active ingredient) | - | - | - | - | Death is not observed at 2000mg/kg (Category 4)(Agricultural-Chemicals abstracts (2002)) using rats, it is outside of Category. Since death is not seen and it cannot be estimated, an active ingredient cannot be classified. |
1 | Acute toxicity (Inhalation: Gases) | Classification not possible (Active ingredient) | - | - | - | - | Solutions is outside of classification since it is the liquid based on GHS definition. Since there is no data about active ingredient, it cannot be classified. |
1 | Acute toxicity (Inhalation: Vapours) | Classification not possible | - | - | - | - | No data available |
1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible | - | - | - | - | There is a rat dust inhalation test result (Agricultural-Chemicals abstracts (2002)), that contains 57% of calcium cyanamide. And it is not a test result of cyanamide active ingredient, it cannot be classified. |
2 | Skin corrosion/irritation | Not classified (about 10% liquid products) | - | - | - | - | Based on the test result of rabbit examination (solution with 13.33% purity), irritation was not observed(Agricultural-Chemicals abstracts (2002)), and it was classified as out of Category. |
3 | Serious eye damage/eye irritation | Not classified (about 10% liquid products) | - | - | - | - | It was carried out the outside of Category by the report that cyanamide 13.33% solution was judged not to indicate irritation to eye of rabbit (Agricultural-Chemicals abstracts (2002)). |
4 | Respiratory sensitization | Classification not possible | - | - | - | - | Since there is no information on respiratory sensitization, it cannot be classified. |
4 | Skin sensitization | Category 1 (about 10% liquid products) | Warning | H317: May cause an allergic skin reaction (about 10% liquid products) |
P302+P352: IF ON SKIN: Wash with plenty of soap and water. P333+P313: If skin irritation or rash occurs: Get medical advice/attention. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P272: Contaminated work clothing should not be allowed out of the workplace. P280: Wear protective gloves/protective clothing/eye protection/face protection. P321: Specific treatment (see ... on this label). P363: Wash contaminated clothing before reuse. P501: Dispose of contents/container to ... |
Skin sensitization was set to Category 1 because it was identified positive against the liquid solution of 13.34% in the test result with guinea pigs(Agricultural Chemicals abstracts (2002)). | |
5 | Germ cell mutagenicity | Category 2 | Warning | H341: Suspected of causing genetic defects |
P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ... |
It was judged to have clastogenic activity for the in vivo test and mammals cultivation cells (Agrichemical Abstracts (2002)), therefore we classified it as Category 2. | |
6 | Carcinogenicity | Classification not possible | - | - | - | - | Since there is no information of animal examination data and an evaluation organization, it cannot classify. |
7 | Reproductive toxicity | Classification not possible | - | - | - | - | Classification not possible due to lack of data on tests to reproduction and teratogenicity tests. |
8 | Specific target organ toxicity - Single exposure | Classification not possible | - | - | - | - | No data available. |
9 | Specific target organ toxicity - Repeated exposure | Classification not possible | - | - | - | - | Although the oral test result of a rat (Agricultural Chemicals abstracts (2002)) is available, since given dose etc. is unknown, it cannot be classified. |
10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available on chemical pneumonia and a dynamic viscosity |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Category 3 | - | - | H402: Harmful to aquatic life |
P273: Avoid release to the environment. P501: Dispose of contents/container to ... |
It was classified into Category 3 from 48-hour EC50=33.5mg/L of Crustacea (Daphnia magna) (Agricultural Chemical Registration Data, 2002). |
11 | Hazardous to the aquatic environment (Long-term) | Category 3 | - | - | H412: Harmful to aquatic life with long lasting effects |
P273: Avoid release to the environment. P501: Dispose of contents/container to ... |
Classified into Category 3, since acute toxicity was Category 3 and rapid degradability is unknown, though supposed less bio-accumulative (log Kow=-0.82 (PHYSPROP Database, 2005)). |
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference Manual |
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Definitions / Abbreviations |
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Model SDS by MHLW |
MHLW Website (in Japanese Only) |