GHS Classification Result
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：2-Methylpropyl acetate
CAS：110-19-0
Result：
| ID: | 727 |
| Classifier: | Inter-ministerial Committee on GHS |
| Year Classified: | FY2006 |
| Reference Manual: | GHS Classification Manual （10 Feb, 2006） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable | - | - | - | - | There are no chemical groups associated with explosive properties present in the molecules. |
| 2 | Flammable gases （including chemically unstable gases） | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
| 4 | Oxidizing gases | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 5 | Gases under pressure | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 6 | Flammable liquids | Category 2 |
|
Danger | H225: Highly flammable liquid and vapour |
P303+P361+P353: IF ON SKIN （or hair）: Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P370+P378: In case of fire: Use ... for extinction. P403+P235: Store in a well-ventilated place. Keep cool. P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P233: Keep container tightly closed. P240: Ground/bond container and receiving equipment. P241: Use explosion-proof electrical/ventilating/lighting/.../equipment. P242: Use only non-sparking tools. P243: Take precautionary measures against static discharge. P280: Wear protective gloves/protective clothing/eye protection/face protection. P501: Dispose of contents/container to ... |
Flash point: <23degC, Boiling point: >35degC |
| 7 | Flammable solids | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | There are no chemical groups associated with explosive or self-reactive properties present in the molecule. |
| 9 | Pyrophoric liquids | Not classified | - | - | - | - | UNRTDG Class: 3 |
| 10 | Pyrophoric solids | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 11 | Self-heating substances and mixtures | Not classified | - | - | - | - | UNRTDG Class: 3 (flammable liquids) |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | The chemical structure of the substance does not contain metals or metaloids(B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At). |
| 13 | Oxidizing liquids | Not applicable | - | - | - | - | Organic compounds containing oxygen (but not chlorine and fluorine) chemically bonded only to carbon (but not to other elements). |
| 14 | Oxidizing solids | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 15 | Organic peroxides | Not applicable | - | - | - | - | Containing no -0-0- structure |
| 16 | Corrosive to metals | Not classified | - | - | - | - | It is judged that there is no corrosion behavior. "steel, stainless steels and aluminum are durable as a container. Existence of acetylene will corrode copper. (Hommmel (1991)) " |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Not classified | - | - | - | - | Not classified because of SPECIES: Rat; 15400mg/kg; REFERENCE SOURCE: DFGOTvol.19 (2003) |
| 1 | Acute toxicity （Dermal） | Not classified | - | - | - | - | It was set as the outside of Category from rabbit data of LD50 >17400mg/kg (DFGOT vol.19 (2003)). |
| 1 | Acute toxicity （Inhalation: Gases） | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 1 | Acute toxicity （Inhalation: Vapours） | Category 5 | - | Warning | H333: May be harmful if inhaled | P304+P312: IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. | The value with which 4 out of 6 animals died was 8000ppm (37.93 mg/L) (DFGOT vol.19 (2003)), and LC50 was presumed to be larger than 5000 ppm of Category 4. So it was classified as Category 5. |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Classification not possible | - | - | - | - | No data available |
| 2 | Skin corrosion/irritation | Category 3 | - | Warning | H316: Causes mild skin irritation | P332+P313: If skin irritation occurs: Get medical advice/attention. | There was also a report of negative on humans (DFGOTvol.19 (2003)). But it was classified as Category 3 based on the results of MILD and Moderate as a result of animal examination on rabbits (RTECS (2004)). |
| 3 | Serious eye damage/eye irritation | Category 2B | - | Warning | H320: Causes eye irritation |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P264: Wash ... thoroughly after handling. |
It was set as Category 2B by the test results of Moderate (RTECS (2004)) and slight eye irritation (DFGTO vol.19 (2003)) to the rabbit. |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | - | Since there is no report, respiratory sensitization cannot be classified. |
| 4 | Skin sensitization | Not classified | - | - | - | - | Skin sensitization was put outside of the division,based on the report that sensitization was not identified by the the skin sensitization examination in both humans and animals(DFGOT vol.19, (2003)). |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | There was a negative result (DFGOT vol.19 (2003)) for in vitro test, however, there were no in vivo test results. Therefore we presupposed that we could not classify it according to the technical guideline. |
| 6 | Carcinogenicity | Classification not possible | - | - | - | - | No data with IARC, NTP, Japan Society for Occupational Health, etc. |
| 7 | Reproductive toxicity | Classification not possible | - | - | - | - | There is no valid data of reproductive toxicity and developmental toxicity. However, it is classified into the pregnancy risk group C in MAK (DFGOTvol.19 (2003)). |
| 8 | Specific target organ toxicity - Single exposure | Classification not possible | - | - | - | - | Insufficient data available. |
| 9 | Specific target organ toxicity - Repeated exposure | Classification not possible | - | - | - | - | Classification not possible due to lack of data |
| 10 | Aspiration hazard | Classification not possible | - | - | - | - | Classification not possible due to lack of data on an animal experimentation, though the dynamic viscosity: 0.80mm2/s at 20degC. |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Category 3 | - | - | H402: Harmful to aquatic life |
P273: Avoid release to the environment. P501: Dispose of contents/container to ... |
It was classified into Category 3 from 96-hour LC50=17mg/L of fishes (Oryzias latipes) (MOE eco-toxicity tests of chemicals, 1999). |
| 11 | Hazardous to the aquatic environment （Long-term） | Not classified | - | - | - | - | Since rapidly degrading (it hydrolyzed and acetic acid and iso-butanol are generated), and supposed less bio-accumulative (log Kow=1.78 (PHYSPROP Database, 2005)). |
NOTE:
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* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
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Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website （in Japanese Only） |
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Model SDS by MHLW |
MHLW Website （in Japanese Only） |