GHS Classification Result

Chemical Name:Ammonium sulphamate
CAS:7773-06-0

Result:
ID: 636
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual (10 Feb, 2006)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecules.
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Solid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Solid (GHS definition)
5 Gases under pressure Not applicable - - - - Solid (GHS definition)
6 Flammable liquids Not applicable - - - - Solid (GHS definition)
7 Flammable solids Not classified - - - - Non-combustible (Weiss (2nd, 1985))
8 Self-reactive substances and mixtures Classification not possible - - - - Classification not possible due to lack of data, though the substance contains S=O bonds as chemical groups with self-reactive properties present.
9 Pyrophoric liquids Not applicable - - - - Solid (GHS definition)
10 Pyrophoric solids Not classified - - - - Non-combustible (Weiss, 2nd, 1985)
11 Self-heating substances and mixtures Not classified - - - - Non-combustible (Weiss, 2nd, 1985)
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable - - - - The chemical structure of the substance does not contain metals or metaloids(B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13 Oxidizing liquids Not applicable - - - - Solid (GHS definition)
14 Oxidizing solids Classification not possible - - - - No data available
15 Organic peroxides Not applicable - - - - Inorganic substance
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Category 5 - Warning H303: May be harmful if swallowed P312: Call a POISON CENTER or doctor/physician if you feel unwell. Category 5 based on SPECIES: Rat; ENDPOINT: LD50;VALUE:3900 mg/kg; REFERENCE SOURCE: ACGIH (7th, 2001)
1 Acute toxicity (Dermal) Classification not possible - - - - No data available
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Solid (GHS definition)
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - - No data available
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - - No data available
2 Skin corrosion/irritation Category 3 - Warning H316: Causes mild skin irritation P332+P313: If skin irritation occurs: Get medical advice/attention. Animal studies show no skin irritation (ACGIH (7th, 2001), HSDB (2005)) or slight reaction with repeated administration (HSDB (2005), TOXCENTER (2005)). There are statements that there was no skin irritation (HSDB (2005), HSFS (2001)) and that skin is irritated (ACGIH (7th, 2001), HSDB (2005)) on humans. Based on the above information, skin irritativeness was thought to be weak, and it was classified as Category 3.
3 Serious eye damage/eye irritation Category 2A-2B Warning H319: Causes serious eye irritation P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
It was set as Category 2A-2B based on the statement that redness, pain and irritation were produced in an eye of humans (HSDB (2005), ICSC (2004), HSFS (2001)).
4 Respiratory sensitization Classification not possible - - - - No data
4 Skin sensitization Classification not possible - - - - No data
5 Germ cell mutagenicity Classification not possible - - - - We found a negative result by in vitro mutagenicity examination (reverse mutation test using bacteria) (TOXCENTER (2005)), however, we found no in vivo data, therefore we could not classify it for the insufficiecy of data.
6 Carcinogenicity Classification not possible - - - - No data available
7 Reproductive toxicity Classification not possible - - - - Since although there is a description that in 3 generation reproduction toxicity test, it is not observed reproduction toxicity at dose below 25mg/kg/day (converted from the concentration of 500 ppm in feeding administration) (IRIS (2002)) and there is no toxicity in histopathological and at indexies of reproduction and lactation with dose below 25mg/kg/day (TOXCENTER (2005)), a possibility of reproductive toxicity in the feeding administration of higher concentrations than 500 ppm cannot be denied, it was deemed unable to be classified since data was insufficient.
8 Specific target organ toxicity - Single exposure Category 3 (Respiratory tract irritation, Narcotic effects) Warning H335: May cause respiratory irritation (respiratory tract irritation, narcotic effects)
H336: May cause drowsiness or dizziness (respiratory tract irritation, narcotic effects)
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P271: Use only outdoors or in a well-ventilated area.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P405: Store locked up.
P501: Dispose of contents/container to ...
It was set as Category 3 (respiratory irritation, anesthesia action) based on the statement that there is respiratory irritation in humans (HSFS (2001), HSDB (2005)), and the statement of the anesthesia action in a mouse (RTECS (2005)).
9 Specific target organ toxicity - Repeated exposure Not classified - - - - Since in the rats oral administrations test, toxic effects was not admitted over 250 mg/kg/day or the upper limit of the guidance value range of Cagegory 2 (10-100 mg/kg/day) (ACGIH (7th, 2001), HSDB (2005)), it was classified to as the outside of Category.
10 Aspiration hazard Classification not possible - - - - No data available

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Classification not possible - - - - Insufficient data available.
11 Hazardous to the aquatic environment (Long-term) Classification not possible - - - - Classification not possible due to lack of data


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model SDS by MHLW

MHLW Website (in Japanese Only)


To GHS Information