NITE - Chemical Management Field

GHS Classification Result

Chemical Name：Nitric acid
CAS：7697-37-2

Result：


ID:	597
Classifier:	Inter-ministerial Committee on GHS
Year Classified:	FY2006
Reference Manual:	GHS Classification Manual （10 Feb, 2006）

PHYSICAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Explosives	Not classified	-	-	-	-	Not an explosive product, though containing chemical groups associated with explosive properties present.
2	Flammable gases （including chemically unstable gases）	Not applicable	-	-	-	-	Liquid (GHS definition)
3	Aerosols	Not applicable	-	-	-	-	Not aerosol products
4	Oxidizing gases	Not applicable	-	-	-	-	Liquid (GHS definition)
5	Gases under pressure	Not applicable	-	-	-	-	Liquid (GHS definition)
6	Flammable liquids	Not classified	-	-	-	-	Non-combustible (Hommel, 1991).
7	Flammable solids	Not applicable	-	-	-	-	Liquid (GHS definition)
8	Self-reactive substances and mixtures	Not applicable	-	-	-	-	Although it excludes the grouping relevant to autoreactive in a molecule and includes atomic team which relates to explosibility, it is classified into the oxidizing liquid. So it is excepted from the definition of autoreactive from the statement of the GHS documents 2.8.1.
9	Pyrophoric liquids	Not classified	-	-	-	-	Non-combustible (Hommel, 1991)
10	Pyrophoric solids	Not applicable	-	-	-	-	Liquid (GHS definition)
11	Self-heating substances and mixtures	Not classified	-	-	-	-	Non-combustible (Hommel, 1991)
12	Substances and mixtures which, in contact with water, emit flammable gases	Not applicable	-	-	-	-	The chemical structure of the substance does not contain metals or metaloids(B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13	Oxidizing liquids	Category 3		Warning	H272: May intensity fire; oxidizer	P370+P378: In case of fire: Use ... for extinction. P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P220: Keep/Store away from clothing/.../combustible materials. P221: Take any precaution to avoid mixing with combustibles/... P280: Wear protective gloves/protective clothing/eye protection/face protection. P501: Dispose of contents/container to ...	Category 3 because of UNRTDG Subsidiary risks Class: 5.1, PG III, though it is a strong oxidizing agent (NFPA, 13th, 2002)
14	Oxidizing solids	Not applicable	-	-	-	-	Liquid (GHS definition)
15	Organic peroxides	Not applicable	-	-	-	-	Inorganic compound
16	Corrosive to metals	Classification not possible	-	-	-	-	There is no data and it cannot be classified. (a stainless steel, aluminum, and glass are durable as a container. Steels, Monel metal, nickels and coppers are corroded. There is a description as (Hommmel (1991)) and it is presumed as Category 1.)

HEALTH HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Acute toxicity （Oral）	Classification not possible	-	-	-	-	Although there is a lethal (IUCLID (2000)) statement of 430 mg/kg in humans, there is no other data and it cannot be classified.
1	Acute toxicity （Dermal）	Classification not possible	-	-	-	-	No data available
1	Acute toxicity （Inhalation: Gases）	Not applicable	-	-	-	-	Liquid (GHS definition)
1	Acute toxicity （Inhalation: Vapours）	Classification not possible	-	-	-	-	No data available
1	Acute toxicity （Inhalation: Dusts and mists）	Category 2		Danger	H330: Fatal if inhaled	P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P284: Wear respiratory protection. P310: Immediately call a POISON CENTER or doctor/physician. P320: Specific treatment is urgent （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ...	Nitric acid did not exist as steam and gas, and it considered that all the data of LC50 was mist. Since all of five data were within the range of 0.05 - 0.5mg/L, it was set as Category 2.
2	Skin corrosion/irritation	Category 1A		Danger	H314: Causes severe skin burns and eye damage	P301+P330+P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353: IF ON SKIN （or hair）: Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P310: Immediately call a POISON CENTER or doctor/physician. P321: Specific treatment （see ... on this label）. P363: Wash contaminated clothing before reuse. P405: Store locked up. P501: Dispose of contents/container to ...	There is a description of corrosivity on humans (ICSC (1994)) and (HSDB (2005)), and its UN classification is class 8I, it was classified as Category 1A.
3	Serious eye damage/eye irritation	Category 1		Danger	H318: Causes serious eye damage	P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P280: Wear protective gloves/protective clothing/eye protection/face protection. P310: Immediately call a POISON CENTER or doctor/physician.	There is a statement that if exposed to the human eye, severe burns will take place, and muddiness of a cornea and visual impairment result in vision loss (ACGIH (2001)). And it was set as Category 1 since skin corrosivity / irritation was categoried into Category 1A.
4	Respiratory sensitization	Classification not possible	-	-	-	-	No data available
4	Skin sensitization	Classification not possible	-	-	-	-	No data available
5	Germ cell mutagenicity	Classification not possible	-	-	-	-	Although there is a report of negative results from the in vitro Ames test (DFGOTvol.3 (1991)), the substance cannot be classified because there are no reports about in vivo tests.
6	Carcinogenicity	Classification not possible	-	-	-	-	There is a result in the inhalation exposure test report of two cases using rats that shows no carcinogenicity (DFGOTvol.3 (1991), (IUCLID (2000)). But there is no report of evaluation organizations, such as IARC, therefore it cannot be classified.
7	Reproductive toxicity	Classification not possible	-	-	-	-	Although there is the description that teratogenicity and ferotoxity does not occur and there is only a slight ossification inhibition of cranial bone in embryo in the drinking water administration test to pregnancy rat (IUCLID (2000)), but it is considered as insufficient data for classification, and it is considered as it cannot be classified.
8	Specific target organ toxicity - Single exposure	Category 1 (respiratory system)		Danger	H370: Causes damage to organs (respiratory system)	P307+P311: IF exposed: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ...	According to the statements that when humans inhale the steam generated from nitrate, irritation of the upper airway, coughing, breathing difficulty, pain of the breast or pulmonary are caused depending on the exposure concentration and exposure time (ACGIH (2001), DFGOTvol.3 (1991), ICSC(J), (1994), and HSDB (2005)). So it was classified into Category 1. (respiratory systems).
9	Specific target organ toxicity - Repeated exposure	Category 1 (tooth, respiratory system)		Danger	H372: Cause damage to organs through prolonged or repeated exposure (tooth, respiratory system)	P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ...	According to the statement of the chronic bronchitis by occupation exposure of the steam generated from mist or nitric acid (ACGIH (2001)) and erosion of tooth (ACGIH (2001), (DFGOTvol.3 (1994)), it was classified to as Category 1 (tooth, respiratory system).
10	Aspiration hazard	Category 1		Danger	H304: May be fatal if swallowed and enters airways	P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P331: Do NOT induce vomiting. P405: Store locked up. P501: Dispose of contents/container to ...	It was classified into Category 1 based on the statement that of chemical lobar pneumonia by aspiration (ACGIH (2001)).

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
11	Hazardous to the aquatic environment （Acute）	Classification not possible	-	-	-	-	Insufficient data available.
11	Hazardous to the aquatic environment （Long-term）	Classification not possible	-	-	-	-	Classification not possible due to lack of data

NOTE:

* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：

Reference Manual
Definitions / Abbreviations
Model SDS by MHLW	MHLW Website （in Japanese Only）