GHS Classification Result

Chemical Name：Phosphorus (yellow)
CAS：12185-10-3

Result：
ID: 571
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual （10 Feb, 2006）

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecules.
2 Flammable gases （including chemically unstable gases） Not applicable - - - - Solid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Solid (GHS definition)
5 Gases under pressure Not applicable - - - - Solid (GHS definition)
6 Flammable liquids Not applicable - - - - Solid (GHS definition)
7 Flammable solids Not classified - - - - UNRTDG No. 1381, Class: 4.2, Subsidiary risks Class: Class: 6.1, PG I
8 Self-reactive substances and mixtures Not classified - - - - Classified in UNRTDG No. 1381, Class: 4.2, Subsidiary risks Class: 6.1, PGI
9 Pyrophoric liquids Not applicable - - - - Solid (GHS definition)
10 Pyrophoric solids Category 1 Danger H250: Catches fire spontaneously if exposed to air P335+P334: Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P370+P378: In case of fire: Use ... for extinction.
P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P222: Do not allow contact with air.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P422: Store contents under ... 		UNRTDG No. 1381, Class: 4.2, Subsidiary risks Class: 6.1, PGI
11 Self-heating substances and mixtures Not applicable - - - - Pyrophoric solids
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - - UNRTDG No. 1381, Class: 4.2, Subsidiary risks Class: Class: 6.1, PGI
13 Oxidizing liquids Not applicable - - - - Solid (GHS definition)
14 Oxidizing solids Not applicable - - - - Containing no oxygen , chlorine and fluorine.
15 Organic peroxides Not applicable - - - - Containing no -0-0- structure
16 Corrosive to metals Not classified - - - - UNRTDG No. 1381, Class: 4.2, Subsidiary risks Class: Class: 6.1, PGI

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity （Oral） Category 1 Danger H300: Fatal if swallowed P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P321: Specific treatment （see ... on this label）.
P330: Rinse mouth.
P405: Store locked up.
P501: Dispose of contents/container to ... 		Rat LD50 = 3.76 mg/kg (male), 3.03 mg/kg (female) (ATSDR (1997)). Estimated lethal dose for humans in oral is 1-2 mg/kg (PATTY (5th, 2001), ACGIH (2001), ATSDR (1997), HSDB (2005), IUCLID (2004)). Even if based on any data, it is set as Category 1.
1 Acute toxicity （Dermal） Category 1 Danger H310: Fatal in contact with skin P302+P350: IF ON SKIN: Gently wash with plenty of soap and water.
P262: Do not get in eyes, on skin, or on clothing.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P310: Immediately call a POISON CENTER or doctor/physician.
P322: Specific treatment （see ... on this label）.
P361: Remove/Take off immediately all contaminated clothing.
P363: Wash contaminated clothing before reuse.
P405: Store locked up.
P501: Dispose of contents/container to ... 		Rat LD50 = approx. 29mg/kg and 100mg/kg. The former higher toxicity was adopted and it was set as Category 1.
1 Acute toxicity （Inhalation: Gases） Not applicable - - - - Solid (GHS definition)
1 Acute toxicity （Inhalation: Vapours） Classification not possible - - - - No data available
1 Acute toxicity （Inhalation: Dusts and mists） Classification not possible - - - - No data available
2 Skin corrosion/irritation Category 1A-1C Danger H314: Causes severe skin burns and eye damage P301+P330+P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353: IF ON SKIN （or hair）: Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P310: Immediately call a POISON CENTER or doctor/physician.
P321: Specific treatment （see ... on this label）.
P363: Wash contaminated clothing before reuse.
P405: Store locked up.
P501: Dispose of contents/container to ... 		There are descriptions that it causes burn when contacting human skin (ACGIH (2001), ATSDR (1997), ICSC (2004)), and that it originates not only in thermals but in corrosive effects (ATSDR (1997)). Moreover, also in the animal studies, it is evaluated as "corrosive" or "necrosis" (IUCLID (2004), ATSDR (1997)). Based on what mentioned above, it was classified as Category 1A-1C.
3 Serious eye damage/eye irritation Category 1 Danger H318: Causes serious eye damage P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P310: Immediately call a POISON CENTER or doctor/physician. 		A serious injury accompanied by a eyelids convulsion, photophobia and lacrimation by touching the human eye, or corneal cloudings is caused (PATTY (5th, 2001), HSDB (2005)). Or redness, a pain, eyesight loss, and a serious burn are indicated (ICSC (2004)). So it was set as Category 1.
4 Respiratory sensitization Classification not possible - - - - No data available
4 Skin sensitization Classification not possible - - - - No data available
5 Germ cell mutagenicity Classification not possible - - - - Classification not possible due to lack of data
6 Carcinogenicity Classification not possible - - - - Classification not possible due to lack of data
7 Reproductive toxicity Category 2 Warning H361: Suspected of damaging fertility or the unborn child P308+P313: IF exposed or concerned: Get medical advice/attention.
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P405: Store locked up.
P501: Dispose of contents/container to ... 		It is described that in the rat study (generation study) with administration covering two reproductive cycles from 80 days before mating, mortality of mother animals was observed with high doses, most of them (13/16) occured during delivery period, and that administration of yellow phosphorus may be the possible cause (IRIS (1991)). Since although concentration of the death to an delivery period is considered to be an adverse effects to reproduction, influence of maternal toxicities cannot be denied, either, it was classified into Category 2. In addition, inhibition of growth and survival of a child was observed in lactation period with the administration starting three weeks before mating and the effect on lactation is suggested as a cause of this (ATSDR (1997)).
8 Specific target organ toxicity - Single exposure Category 1 (liver, kidney, digestive system, blood, central nervous system), Category 3 (respiratory tract irritation) Danger
Warning 		H370: Causes damage to organs (liver, kidney, digestive system, blood, central nervous system)
H335: May cause respiratory irritation (respiratory tract irritation) 		P307+P311: IF exposed: Call a POISON CENTER or doctor/physician.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P321: Specific treatment （see ... on this label）.
P405: Store locked up.
P501: Dispose of contents/container to ...
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P271: Use only outdoors or in a well-ventilated area.
P312: Call a POISON CENTER or doctor/physician if you feel unwell. 		It was classified into Category 1(liver, kidney, digestive systems, hematopoietic systems, central nervous systems), since there are reports or descriptions that it affects to wide range of organs, such as the liver, kidney, gastrointestinal system, haematopoietic system, central nerves by acute exposure of this product to human (ACGIH (2001), PATTY (5th, 2001), IRIS (1991), HSDB (2005)). Moreover, it was classified into Category 3 (respiratory irritant) due to the respiratory irritant by short time exposures is also observed (ATSDR (1997)). In addition, the reason of the death in the examination of mouse is that mucosal swellings or mucus secretions occurred by irritation, the airway was closed and died by suffocation (ATSDR (1997)).
9 Specific target organ toxicity - Repeated exposure Category 1 (bone, blood) Danger H372: Cause damage to organs through prolonged or repeated exposure (bone, blood) P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P314: Get medical advice/attention if you feel unwell.
P501: Dispose of contents/container to ... 		According to human case reports or epidemiological study, a necrosis of a jaw part and bony destruction, so-called "phossy jaw" is reported (IRIS (1991), PATTY (5th, 2001), ATSDR (1997)) , and the denaturation of the mouth and anemia are also reported (PATTY (5th, 2001), ATSDR (1997)).) Moreover, effects on bone is observed also the animal studies (IRIS (1991).). The effects above were considered to be serious toxicity, it was classified in Category 1 (a bone, hematologic).
10 Aspiration hazard Classification not possible - - - - Insufficient data available.

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment （Acute） Category 1 Warning H400: Very toxic to aquatic life P273: Avoid release to the environment.
P391: Collect spillage.
P501: Dispose of contents/container to ... 		It was classified into Category 1 from 96-hour LC50=2microg/L of fishes (Bluegill) (AQUIRE, 2003).
11 Hazardous to the aquatic environment （Long-term） Category 1 Warning H410: Very toxic to aquatic life with long lasting effects P273: Avoid release to the environment.
P391: Collect spillage.
P501: Dispose of contents/container to ... 		Classified into Category 1, since acute toxicity was Category 1, and behavior in water and bioaccumulative potential are unknown.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：
Reference Manual
Definitions / Abbreviations
Model SDS by MHLW

 MHLW Website （in Japanese Only）

To GHS Information