Chemical Name：Mixture of 2,4-dinitro-6-octylphenyl crotonate and 2,6-dinitro-4-octylphenyl crotonate (octyl=1-methylheptyl,1-ethylhexyl,1-propylpentyl); Dinocap; DPC
CAS：131-72-6

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Acute toxicity （Oral）	Category 4		Warning	H302: Harmful if swallowed	P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P330: Rinse mouth. P501: Dispose of contents/container to ...	Based on the LD50 value of 829mg/kg calculated from the rat LD50 (oral route) of 980mg/kg, 950mg/kg, 1,190mg/kg (HSDB (2006)) and 766mg/kg (RTECS (2006)).
1	Acute toxicity （Dermal）	Not classified	-	-	-	-	Based on the rabbit LD50 (dermal route) value of 9,400mg/kg (RTECS (2006)).
1	Acute toxicity （Inhalation: Gases）	Not applicable	-	-	-	-	Due to the fact that the substance is "liquid" according to the GHS definition and inhalation of its gas is not expected.
1	Acute toxicity （Inhalation: Vapours）	Category 1		Danger	H330: Fatal if inhaled	P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P284: Wear respiratory protection. P310: Immediately call a POISON CENTER or doctor/physician. P320: Specific treatment is urgent （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ...	Based on the rat LC50 value of 24ppm (4 hours), calculated from the testing data of rat LC50 (inhalation of vapour) of 0.36mg/L (4 hours) (RTECS (2006)), was lower than the saturated vapour concentration (52,800ppm) under a saturated vapour pressure of 0.00533mPa (25degC) (Howard (1997)), the substance was considered as "vapour containing substantially no mist" and was classified based on standard values expressed in ppm.
1	Acute toxicity （Inhalation: Dusts and mists）	Classification not possible	-	-	-	-	No data available
2	Skin corrosion/irritation	Category 2		Warning	H315: Causes skin irritation	P302+P352: IF ON SKIN: Wash with plenty of soap and water. P332+P313: If skin irritation occurs: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P321: Specific treatment （see ... on this label）. P362: Take off contaminated clothing and wash before reuse.	Based on the description of the human health effects (exposure duration unknown) (HSDB (2006)): "They are only moderately irritating to the skin and mucous membranes."
3	Serious eye damage/eye irritation	Classification not possible	-	-	-	-	No data available
4	Respiratory sensitization	Classification not possible	-	-	-	-	No data available
4	Skin sensitization	Category 1		Warning	H317: May cause an allergic skin reaction	P302+P352: IF ON SKIN: Wash with plenty of soap and water. P333+P313: If skin irritation or rash occurs: Get medical advice/attention. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P272: Contaminated work clothing should not be allowed out of the workplace. P280: Wear protective gloves/protective clothing/eye protection/face protection. P321: Specific treatment （see ... on this label）. P363: Wash contaminated clothing before reuse. P501: Dispose of contents/container to ...	Based on the description of the human health effects (HSDB (2006) and ICSC (J) (1997)): "Skin sensitization: positive."
5	Germ cell mutagenicity	Not classified	-	-	-	-	Based on the absence of data on multi-generation mutagenicity tests and germ cell mutagenicity tests in vivo, and negative data on somatic cell mutagenicity tests in vivo (chromosome aberration tests), described in JMPR (1989) and JMPR (1998).
6	Carcinogenicity	Classification not possible	-	-	-	-	Classification not possible based on expert judgment in the absence of existing classification, though some toxicity data are available.
7	Reproductive toxicity	Category 1B		Danger	H360: May damage fertility or the unborn child	P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ...	Based on the evidence of increased pup mortality and fetal malformation (cleft palate, abnormal inner ear) at non-parentally toxic doses in mouse teratogenicity studies, described in JMPR (1989).
8	Specific target organ toxicity - Single exposure	Classification not possible	-	-	-	-	Insufficient data available
9	Specific target organ toxicity - Repeated exposure	Category 1 (liver), Category 2 (kidney)		Danger Warning	H372: Cause damage to organs through prolonged or repeated exposure (liver) H373: May cause damage to organs through prolonged or repeated exposure (kidney)	P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ...	Based on the evidence from animal studies: "necrosis was found in the liver" (JMPR (1998)), "histological changes were noted in the liver and kidneys" (HSDB (2006)). The effects on experimental animals were observed at dosing levels within the guidance value ranges for Categories 1 and 2.
10	Aspiration hazard	Classification not possible	-	-	-	-	No data available