GHS Classification Result

Chemical Name:Bis(hydrogenated tallow)dimethylammonium chloride
CAS:61789-80-8

Result:
ID: 465
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual (10 Feb, 2006)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - Containing no chemical groups with explosive properties
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Classified as "solid" according to GHS definition
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Classified as "solid" according to GHS definition
5 Gases under pressure Not applicable - - - - Classified as "solid" according to GHS definition
6 Flammable liquids Not applicable - - - - Classified as "solid" according to GHS definition
7 Flammable solids Classification not possible - - - - Classification not possible due to lack of data, though distearyldimethylammonium chloride (C38H80ClN), a main component of commercial products, is classified as flammable according to ICSC (2004).
8 Self-reactive substances and mixtures Not applicable - - - - Containing no chemical groups with explosive or self-reactive properties
9 Pyrophoric liquids Not applicable - - - - Classified as "solid" according to GHS definition
10 Pyrophoric solids Classification not possible - - - - No data available
11 Self-heating substances and mixtures Classification not possible - - - - Test methods applicable to substances which begin to decompose at temperatures lower than the test temperatures are not available (distearyldimethylammonium chloride (C38H80ClN), a main component of commercial products, decomposes at 135degC, which is lower than the melting point (ICSC, 2004), test temperature: 140degC).
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable - - - - Containing no metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At)
13 Oxidizing liquids Not applicable - - - - Classified as "solid" according to GHS definition
14 Oxidizing solids Classification not possible - - - - Classification not possible due to lack of data, though being organic compounds containing chlorine bound to elements other than carbon and hydrogen
15 Organic peroxides Not applicable - - - - Organic compounds containing no "-O-O-" structure
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available (distearyldimethylammonium chloride (C38H80ClN), a main component of commercial products, decomposes at 135degC, which is lower than the melting point (ICSC, 2004), test temperature: 55degC).

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Not classified - - - - Based on the rat LD50 (oral route) value of 11,300mg/kg (CERI-NITE Hazard Assessment No.78 (2005)).
1 Acute toxicity (Dermal) Not classified - - - - Based on the rat LD50 (dermal route) value of >2,000mg/kg (CERI-NITE Hazard Assessment No.78 (2005)).
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Due to the fact that the substance is "solid" according to the GHS definition and inhalation of its gas is not expected.
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - - No data available
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - - No data available
2 Skin corrosion/irritation Not classified - - - - Based on the description in the report on rabbit skin irritation tests performed in accordance with OECD TG404 (CERI-NITE Hazard Assessment No.78 (2005)): 72 hour application of the substance (the test material content: 97%) "showed no evidence of irritation."
3 Serious eye damage/eye irritation Category 1 Danger H318: Causes serious eye damage P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P310: Immediately call a POISON CENTER or doctor/physician.
Based on the description in the report on rabbit eye irritation tests performed in accordance with OECD TG405 (CERI-NITE Hazard Assessment No.78 (2005)): "severe irritation." Although classified as Category 1-2A in the absence of data on reversibility, the substance should be placed in Category 1 from the viewpoint of safety.
4 Respiratory sensitization Classification not possible - - - - No data available
4 Skin sensitization Not classified - - - - Based on three epidemiological case reports that provide no evidence of skin sensitization in humans (CERI-NITE Hazard Assessment No.78 (2005)) along with negative results of guinea pig skin sensitization tests performed according to Maximization Method.
5 Germ cell mutagenicity Classification not possible - - - - Based on the absence of data on multi-generation mutagenicity tests, germ/somatic cell mutagenicity tests in vivo and germ/somatic cell genotoxicity tests in vivo, and no positive data on mutagenicity tests in vitro (several indices), described in CERI-NITE Hazard Assessment No.78 (2005) and SIDS (1996).
6 Carcinogenicity Classification not possible - - - - No data available
7 Reproductive toxicity Category 2 Warning H361: Suspected of damaging fertility or the unborn child P308+P313: IF exposed or concerned: Get medical advice/attention.
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P405: Store locked up.
P501: Dispose of contents/container to ...
Based on the evidence of reduced fertility of parental animals and reduced viability of pups at doses producing parental toxicity (or in the absence of data on parental toxicity) in rat reproductive toxicity studies and mouse teratogenicity studies, described in CERI-NITE Hazard Assessment No.78 (2005).
8 Specific target organ toxicity - Single exposure Classification not possible - - - - Insufficient data available
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - Insufficient data available
10 Aspiration hazard Classification not possible - - - - No data available

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Category 1 Warning H400: Very toxic to aquatic life P273: Avoid release to the environment.
P391: Collect spillage.
P501: Dispose of contents/container to ...
It was classified into Category 1 from 48 hours LC50=0.16mg/L of the crustacea (Daphnia magna) (CERI/NITE Hazard Assessment Report (preliminary version), 2006).
11 Hazardous to the aquatic environment (Long-term) Category 1 Warning H410: Very toxic to aquatic life with long lasting effects P273: Avoid release to the environment.
P391: Collect spillage.
P501: Dispose of contents/container to ...
Although acute toxicity is Category 1 and bio-accumulation is low (BCF=13(CERI/NITE Hazard Assessment Report (preliminary version), 2006)), since there was no rapidly degrading (the decomposition by BOD: 0%(Existing Chemical Safety Inspections Data)), it was classified into Category 1.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model Label by MHLW

MHLW Website (in Japanese Only)

Model SDS by MHLW

MHLW Website (in Japanese Only)


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