GHS Classification Result
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：Dichloropentafluoropropane; HCFC-225
CAS：
Result：
| ID: | 410 |
| Classifier: | Inter-ministerial Committee on GHS |
| Year Classified: | FY2006 |
| Reference Manual: | GHS Classification Manual （10 Feb, 2006） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable | - | - | - | - | Containing no chemical groups with explosive properties |
| 2 | Flammable gases （including chemically unstable gases） | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition (3,3-dichloro-1,1,1,2,2-pentafluoropropane, 1,3-dichloro-1,1,2,2,3-pentafluoropropane) |
| 3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
| 4 | Oxidizing gases | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition (3,3-dichloro-1,1,1,2,2-pentafluoropropane, 1,3-dichloro-1,1,2,2,3-pentafluoropropane) |
| 5 | Gases under pressure | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition (3,3-dichloro-1,1,1,2,2-pentafluoropropane, 1,3-dichloro-1,1,2,2,3-pentafluoropropane) |
| 6 | Flammable liquids | Not classified | - | - | - | - | Non-flammable (PRTR Chemicals DB (2001)) |
| 7 | Flammable solids | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition (3,3-dichloro-1,1,1,2,2-pentafluoropropane, 1,3-dichloro-1,1,2,2,3-pentafluoropropane) |
| 8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | Containing no chemical groups with explosive or self-reactive properties |
| 9 | Pyrophoric liquids | Not classified | - | - | - | - | Non-flammable (PRTR Chemicals DB (2001)). |
| 10 | Pyrophoric solids | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition (3,3-dichloro-1,1,1,2,2-pentafluoropropane, 1,3-dichloro-1,1,2,2,3-pentafluoropropane) |
| 11 | Self-heating substances and mixtures | Not classified | - | - | - | - | Non-flammable (PRTR Chemicals DB (2001)). |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | Containing no metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At) |
| 13 | Oxidizing liquids | Not applicable | - | - | - | - | Organic compounds containing fluorine and chlorine (but not oxygen), with the fluorine and chlorine bound to carbon and hydrogen (but not to other elements) |
| 14 | Oxidizing solids | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition (3,3-dichloro-1,1,1,2,2-pentafluoropropane, 1,3-dichloro-1,1,2,2,3-pentafluoropropane) |
| 15 | Organic peroxides | Not applicable | - | - | - | - | Organic compounds containing no "-O-O-" structure |
| 16 | Corrosive to metals | Classification not possible | - | - | - | - | Test methods applicable to gaseous substances are not available (boiling point: 51.1degC (3,3-dichloro-1,1,1,2,2-pentafluoropropane, HSDB (2006), test temperature: 55degC). As for the isomers with boiling point of >55degC, classification is not possible due to lack of data. |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Not classified | - | - | - | - | Based on the rat LD50 (oral route) value of >5,000mg/kg (RTECS (2006)) (1,3-dichloro-1,1,2,2,3-pentafluoropropane, and 3,3-dichloro-1,1,1,2,2-pentafluoropropane) |
| 1 | Acute toxicity （Dermal） | Classification not possible | - | - | - | - | Based on the available rat LD50 (dermal route) of >2,000mg/kg (RTECS (2006)), the substance can be "Not classified" or classified as Category 5. However, there are insufficient data available to serve as a basis for classification into Category 5. (1,3-dichloro-1,1,2,2,3-pentafluoropropane, and 3,3-dichloro-1,1,1,2,2-pentafluoropropane) |
| 1 | Acute toxicity （Inhalation: Gases） | Not applicable | - | - | - | - | Due to the fact that the substance is a liquid according to the GHS definition and inhalation of its gas is not expected. |
| 1 | Acute toxicity （Inhalation: Vapours） | Category 5 | - | Warning | H333: May be harmful if inhaled | P304+P312: IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. | Based on the rat LC50 (inhalation of vapour) value of 262.78mg/L (4 hours) (RTECS (2006)) was lower than 90% of the saturated vapour concentration (377,000ppm) under a saturated vapour pressure of 286mmHg (25degC) [equivalent to 38.1kPa (25degC)] (HSDB (2006)), the substance was considered as "vapour" and was classified into Category 5. (1,3-dichloro-1,1,2,2,3-pentafluoropropane) Based on the rat LC50 (inhalation of vapour) value of 309.6mg/L (4 hours) (RTECS (2006)) was lower than 90% of the saturated vapour concentration (317,000ppm) under a saturated vapour pressure of 240mmHg (25degC) [equivalent to 32.0kPa (25degC)] (HSDB (2006)), the substance was considered as "vapour" and was classified into Category 5. (3,3-dichloro-1,1,1,2,2-pentafluoropropane) |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Classification not possible | - | - | - | - | No data available |
| 2 | Skin corrosion/irritation | Classification not possible | - | - | - | - | No data available |
| 3 | Serious eye damage/eye irritation | Classification not possible | - | - | - | - | No data available |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available |
| 4 | Skin sensitization | Classification not possible | - | - | - | - | No data available |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | No data available |
| 6 | Carcinogenicity | Classification not possible | - | - | - | - | No data available |
| 7 | Reproductive toxicity | Classification not possible | - | - | - | - | No data available |
| 8 | Specific target organ toxicity - Single exposure | Category 3 （Narcotic effects, Respiratory tract irritation） |
|
Warning |
H335: May cause respiratory irritation (narcotic effects, respiratory tract irritation) H336: May cause drowsiness or dizziness (narcotic effects, respiratory tract irritation) |
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P405: Store locked up. P501: Dispose of contents/container to ... |
Based on the evidence from animal studies including "somnolency," and "structural or functional changes in the trachea or bronchi" (RTECS (2006)). |
| 9 | Specific target organ toxicity - Repeated exposure | Classification not possible | - | - | - | - | Insufficient data available |
| 10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Classification not possible | - | - | - | - | No data available |
| 11 | Hazardous to the aquatic environment （Long-term） | Classification not possible | - | - | - | - | No data available |
NOTE:
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* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
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Reference Manual |
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Definitions / Abbreviations |