Chemical Name:Sodium dichromate
CAS:10588-01-9
ID: | 260 |
Classifier: | Inter-ministerial Committee on GHS |
Year Classified: | FY2006 |
Reference Manual: | GHS Classification Manual (10 Feb, 2006) |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
1 | Explosives | Not applicable | - | - | - | - | There are no chemical groups associated with explosive properties present in the molecules. |
2 | Flammable gases (including chemically unstable gases) | Not applicable | - | - | - | - | Solid (GHS definition) |
3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
4 | Oxidizing gases | Not applicable | - | - | - | - | Solid (GHS definition) |
5 | Gases under pressure | Not applicable | - | - | - | - | Solid (GHS definition) |
6 | Flammable liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
7 | Flammable solids | Not classified | - | - | - | - | Non-combustible (Weiss, 2nd, 1985; ICSC(J), 2005) |
8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | There are no chemical groups associated with explosive or self-reactive properties present in the molecule. |
9 | Pyrophoric liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
10 | Pyrophoric solids | Not classified | - | - | - | - | Non-combustible (Weiss, 2nd, 1985; ICSC(J), 2005) |
11 | Self-heating substances and mixtures | Not classified | - | - | - | - | Non-combustible (Weiss(2nd, 1985), ICSC(J) (2005)) |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified | - | - | - | - | Not react with water. (Weiss, 2nd, 1985) |
13 | Oxidizing liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
14 | Oxidizing solids | Classification not possible | - | - | - | - | Classification not possible due to lack of data, though well-known as a strong oxidizing agent (ICSC(J), 2005) |
15 | Organic peroxides | Not applicable | - | - | - | - | Inorganic substance |
16 | Corrosive to metals | Classification not possible | - | - | - | - | Test methods applicable to solid substances are not available. |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Category 2 | Danger | H300: Fatal if swallowed |
P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment (see ... on this label). P330: Rinse mouth. P405: Store locked up. P501: Dispose of contents/container to ... |
SPECIES: Rat ENDPOINT: LD50 VALUE: 46 mg/kg REFERENCE SOURCE: EU-RAR (2005) | |
1 | Acute toxicity (Dermal) | Category 3 | Danger | H311: Toxic in contact with skin |
P302+P352: IF ON SKIN: Wash with plenty of soap and water. P280: Wear protective gloves/protective clothing/eye protection/face protection. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P322: Specific treatment (see ... on this label). P361: Remove/Take off immediately all contaminated clothing. P363: Wash contaminated clothing before reuse. P405: Store locked up. P501: Dispose of contents/container to ... |
It was set as Category 3 based on the rabbit LD50= 960mg/kg (EU-RAR (2005)). | |
1 | Acute toxicity (Inhalation: Gases) | Not applicable | - | - | - | - | Solid (GHS definition) |
1 | Acute toxicity (Inhalation: Vapours) | Classification not possible | - | - | - | - | No data available |
1 | Acute toxicity (Inhalation: Dusts and mists) | Category 2 | Danger | H330: Fatal if inhaled |
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P284: Wear respiratory protection. P310: Immediately call a POISON CENTER or doctor/physician. P320: Specific treatment is urgent (see ... on this label). P405: Store locked up. P501: Dispose of contents/container to ... |
It was set as category 2 based on rat LC50 = 0.2mg/L (EU-RAR (2005)). | |
2 | Skin corrosion/irritation | Category 1 | Danger | H314: Causes severe skin burns and eye damage |
P301+P330+P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P310: Immediately call a POISON CENTER or doctor/physician. P321: Specific treatment (see ... on this label). P363: Wash contaminated clothing before reuse. P405: Store locked up. P501: Dispose of contents/container to ... |
It was classified as Category 1 based on the erythema, edema and corrosion seen on rabbits (EU-RAR (2005), IUCLID (2000)) and the ulcer and the burn seen on humans (EHC 61 (1988)). | |
3 | Serious eye damage/eye irritation | Category 1 | Danger | H318: Causes serious eye damage |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P280: Wear protective gloves/protective clothing/eye protection/face protection. P310: Immediately call a POISON CENTER or doctor/physician. |
It was set as category 1 based on what the necrosis was looked at by the human conjunctiva, erosion was looked at by the corneal (EU-RAR (2005)), and severe irritation was seen for with the rabbit (IUCLID (2000)). | |
4 | Respiratory sensitization | Category 1 | Danger | H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled |
P304+P341: IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. P342+P311: If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P285: In case of inadequate ventilation wear respiratory protection. P501: Dispose of contents/container to ... |
Based on the fact that asthna can be identified in humans (EHC 61 (1988)EU-RAR (2005)), it was referred to as Ctegory 1. | |
4 | Skin sensitization | Category 1 | Warning | H317: May cause an allergic skin reaction |
P302+P352: IF ON SKIN: Wash with plenty of soap and water. P333+P313: If skin irritation or rash occurs: Get medical advice/attention. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P272: Contaminated work clothing should not be allowed out of the workplace. P280: Wear protective gloves/protective clothing/eye protection/face protection. P321: Specific treatment (see ... on this label). P363: Wash contaminated clothing before reuse. P501: Dispose of contents/container to ... |
Guinea pigs indicated skin sensitization (EU-RAR (2005), DFGOT (1996)), and, based on what is also seen for skin sensitization by humans (EHC 61 (1988)), it was referred to as Category 1. | |
5 | Germ cell mutagenicity | Category 2 | Warning | H341: Suspected of causing genetic defects |
P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ... |
The substance was classified as Category 2 by the guidelines. Based on the positive results from the in vivo chromosome aberration test, micronucleus test and DNA damage test (alkaline elution test) (IARC 49(1999), EU-RAR (2005)). | |
6 | Carcinogenicity | Category 1B | Danger | H350: May cause cancer |
P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ... |
It is classified into 1 according to IARC (1987), and is classified into 2 (2005) in EU. And it was set as Category 1B based on newer European Union category. | |
7 | Reproductive toxicity | Not classified | - | - | - | - | Based on that there is no bad reproductive effect, and bad developmental effect of this material (EU-RAR (2005), IRIS (1998), IUCLID (2000)), it was considered as on the outside of Categry. |
8 | Specific target organ toxicity - Single exposure | Category 1 (liver, kidney), Category 3 (respiratory tract irritation) |
Danger Warning |
H370: Causes damage to organs (liver, kidney) H335: May cause respiratory irritation (respiratory tract irritation) |
P307+P311: IF exposed: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment (see ... on this label). P405: Store locked up. P501: Dispose of contents/container to ... P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P312: Call a POISON CENTER or doctor/physician if you feel unwell. |
Due to the descriptions that the effects to the liver, kidney, and the hematopoietic organ were observed in humans (EU-RAR (2005)), and that respiratory irritantation was observed (EU-RAR (2005)), it was classified into Category 1 (liver, the kidney, hematogenous machine) and into Category 3 (respiratory irritant). | |
9 | Specific target organ toxicity - Repeated exposure | Category 1 (respiratory system, kidney) | Danger | H372: Cause damage to organs through prolonged or repeated exposure (respiratory system, kidney) |
P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ... |
In a rat, in the range of guidance value of Category , respiratory distress is seen (IRIS (1998)), and an harmful effects is seen in airways and lungs (IUCLID (2000)). It was classified in Category 1 (respiratory system, kidney) based on a nasal ulcers (IRIS (1998)), a lung dysfunction (EHC 61 (1998)), ulceration of the nasal septum (EHC 61 (1998)), bronchitis (EHC 61 (1998)), and kidney disorders (IRIS (1998)) in humans being reported. | |
10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Category 1 | Warning | H400: Very toxic to aquatic life |
P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ... |
It was classified into Category 1 from 48-hour EC50=0.112mg/L of Crustacea (Daphnia magna) (EU-RAR, 2003). | |
11 | Hazardous to the aquatic environment (Long-term) | Category 1 | Warning | H410: Very toxic to aquatic life with long lasting effects |
P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ... |
Classified into Category 1, since acute toxicity was Category 1, and it is a metallic compound, behavior in water is unknown., though less bioaccumulative (BCF<36 (existing chemical safety inspections data)). |
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference Manual |
|
Definitions / Abbreviations |
|
Model Label by MHLW |
MHLW Website (in Japanese Only) |
Model SDS by MHLW |
MHLW Website (in Japanese Only) |