Chemical Name:Tetrafluoroethylene
CAS:116-14-3
ID: | 156 |
Classifier: | Inter-ministerial Committee on GHS |
Year Classified: | FY2006 |
Reference Manual: | GHS Classification Manual (10 Feb, 2006) |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
1 | Explosives | Not applicable | - | - | - | - | Classified as "gas" according to GHS definition |
2 | Flammable gases (including chemically unstable gases) | Category 1 | Danger | H220: Extremely flammable gas |
P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P377: Leaking gas fire: Do not extinguish, unless leak can be stopped safely. P381: Eliminate all ignition sources if safe to do so. P403: Store in a well-ventilated place. |
The lower explosion limit is 10vol% (NFPA (13th, 2002)). Those containing stabilizers are classified into Division 2.1 (UN#1081) (UN Recommendations on the Transport of Dangerous Goods). | |
3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
4 | Oxidizing gases | Classification not possible | - | - | - | - | No data available. Those containing stabilizers are classified into Division 2.1 (UN#1081) (UN Recommendations on the Transport of Dangerous Goods). |
5 | Gases under pressure | Liquefied gas | Warning | H280: Contains gas under pressure; may explode if heated | P410+P403: Protect from sunlight. Store in a well-ventilated place. | The boiling point is -75.9degC (Lide (84th, 2003)) and the critical temperature is 33.3degC (HSDB (2006)) - i.e., "liquefied gas." Those containing stabilizers are classified into Division 2.1 (UN#1081) (UN Recommendations on the Transport of Dangerous Goods). | |
6 | Flammable liquids | Not applicable | - | - | - | - | Classified as "gas" according to GHS definition |
7 | Flammable solids | Not applicable | - | - | - | - | Classified as "gas" according to GHS definition |
8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | Classified as "gas" according to GHS definition |
9 | Pyrophoric liquids | Not applicable | - | - | - | - | Classified as "gas" according to GHS definition |
10 | Pyrophoric solids | Not applicable | - | - | - | - | Classified as "gas" according to GHS definition |
11 | Self-heating substances and mixtures | Not applicable | - | - | - | - | Classified as "gas" according to GHS definition |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | Classified as "gas" according to GHS definition |
13 | Oxidizing liquids | Not applicable | - | - | - | - | Classified as "gas" according to GHS definition |
14 | Oxidizing solids | Not applicable | - | - | - | - | Classified as "gas" according to GHS definition |
15 | Organic peroxides | Not applicable | - | - | - | - | Classified as "gas" according to GHS definition |
16 | Corrosive to metals | Classification not possible | - | - | - | - | Test methods applicable to gaseous substances are not available |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Classification not possible | - | - | - | - | No data available |
1 | Acute toxicity (Dermal) | Classification not possible | - | - | - | - | No data available |
1 | Acute toxicity (Inhalation: Gases) | Not classified | - | - | - | - | Based on the LC50 value of 27,900ppm calculated from the testing data of rat LC50 (4-hour inhalation of gas) of 25,000ppm (ACGIH (7th, 2001)), 31,000ppm (CERI Hazard Data 2000-18 (2001)), 40,000ppm (ECETOC JACC42 (2003)), 45,000ppm (ACGIH (7th, 2001)). |
1 | Acute toxicity (Inhalation: Vapours) | Not applicable | - | - | - | - | Due to the fact that the substance is "gas" according to the GHS definition and inhalation of its vapour is not expected. |
1 | Acute toxicity (Inhalation: Dusts and mists) | Not applicable | - | - | - | - | Due to the fact that the substance is "gas" according to the GHS definition and inhalation of its dust/mist is not expected. |
2 | Skin corrosion/irritation | Classification not possible | - | - | - | - | No data available |
3 | Serious eye damage/eye irritation | Category 2B | - | Warning | H320: Causes eye irritation |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P264: Wash ... thoroughly after handling. |
Based on the description in HSDB (2005) of human exposure: "eye contact with the substance causes slight irritation." |
4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available |
4 | Skin sensitization | Classification not possible | - | - | - | - | No data available |
5 | Germ cell mutagenicity | Not classified | - | - | - | - | Based on the absence of data on multi-generation mutagenicity tests and germ cell mutagenicity tests in vivo, and negative data on somatic cell mutagenicity tests in vivo (micronucleus tests), described in NTP DB (Access on Feb., 2006), IARC 71 (1999), CERI Hazard Data 2000-18 (2001) and ACGIH (7th, 2001). |
6 | Carcinogenicity | Category 2 | Warning | H351: Suspected of causing cancer |
P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ... |
Due to the fact that the substance is classified as Category R by NTP (2005), Category A3 by ACGIH (2001) and Group 2B by IARC (1999). | |
7 | Reproductive toxicity | Classification not possible | - | - | - | - | Insufficient data available |
8 | Specific target organ toxicity - Single exposure | Category 2 (kidney, liver) | Warning | H371: May cause damage to organs (kidney, liver) |
P309+P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P405: Store locked up. P501: Dispose of contents/container to ... |
Based on the evidence from animal studies including "increases in BUN, urinary output, glycorrhea, alkalinephosphatase activity and gamma-glutamyltranspeptidase activity at 4,000 and 6,000ppm" (ACGIH (4th, 2001)). The effects on experimental animals were observed at dosing levels within the guidance value ranges for Category 2. | |
9 | Specific target organ toxicity - Repeated exposure | Category 2 (kidney) | Warning | H373: May cause damage to organs through prolonged or repeated exposure (kidney) |
P260: Do not breathe dust/fume/gas/mist/vapours/spray. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ... |
Based on the evidence from animal studies including "renal tubular degeneration in males at 625ppm" (NTP TR450 (1997)). The effects on experimental animals were observed at dosing levels within the guidance value ranges for Category 2. | |
10 | Aspiration hazard | Not applicable | - | - | - | - | Due to the fact that the substance is a gas at ordinary temperatures. |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Classification not possible | - | - | - | - | No data available |
11 | Hazardous to the aquatic environment (Long-term) | Classification not possible | - | - | - | - | No data available |
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference Manual |
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Definitions / Abbreviations |
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Model SDS by MHLW |
MHLW Website (in Japanese Only) |