GHS Classification Result

Chemical Name：Phenylmercury acetate
CAS：62-38-4

Result：
ID: 36
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual （10 Feb, 2006）

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - Containing no chemical groups with explosive properties
2 Flammable gases （including chemically unstable gases） Not applicable - - - - Classified as "solid" according to GHS definition
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Classified as "solid" according to GHS definition
5 Gases under pressure Not applicable - - - - Classified as "solid" according to GHS definition
6 Flammable liquids Not applicable - - - - Classified as "solid" according to GHS definition
7 Flammable solids Not classified - - - - Classified as "flammable" according to ICSC (2000). Classified into Division 6.1 (UN#1674) (UN Recommendations on the Transport of Dangerous Goods)
8 Self-reactive substances and mixtures Not applicable - - - - Containing no chemical groups with explosive or self-reactive properties
9 Pyrophoric liquids Not applicable - - - - Classified as "solid" according to GHS definition
10 Pyrophoric solids Not classified - - - - Classified into Division 6.1 (UN#1674) (UN Recommendations on the Transport of Dangerous Goods)
11 Self-heating substances and mixtures Not classified - - - - Classified into Division 6.1 (UN#1674) (UN Recommendations on the Transport of Dangerous Goods)
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - - Stable to water (water solubility: 0.44g/100mL (20degC), ICSC (2000))
13 Oxidizing liquids Not applicable - - - - Classified as "solid" according to GHS definition
14 Oxidizing solids Not classified - - - - No data available, though being organic compounds containing oxygen bound to carbon and hydrogen. Classified into Division 6.1 by UN Recommendations on the Transport of Dangerous Goods (UN#1674)
15 Organic peroxides Not applicable - - - - Organic compounds containing no "-O-O-" structure
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity （Oral） Category 2 Danger H300: Fatal if swallowed P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P321: Specific treatment （see ... on this label）.
P330: Rinse mouth.
P405: Store locked up.
P501: Dispose of contents/container to ... 		Based on the rat LD50 (oral route) value of 22mg/kg representing the lower of the two testing data, 41mg/kg (RTECS (2005)) and 22mg/kg (HSDB (2005)).
1 Acute toxicity （Dermal） Classification not possible - - - - No data available
1 Acute toxicity （Inhalation: Gases） Not applicable - - - - Due to the fact that the substance is "solid" according to the GHS definition and inhalation of its gas is not expected.
1 Acute toxicity （Inhalation: Vapours） Classification not possible - - - - No data available
1 Acute toxicity （Inhalation: Dusts and mists） Classification not possible - - - - No data available
2 Skin corrosion/irritation Category 2 Warning H315: Causes skin irritation P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P321: Specific treatment （see ... on this label）.
P362: Take off contaminated clothing and wash before reuse. 		Based on the evidence of "reddening, pain, blurred vision and severe deep burn" (ICSC (J) (2005)).
3 Serious eye damage/eye irritation Category 2 Warning H319: Causes serious eye irritation P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection. 		Based on the evidence of "reddening, pain, blurred vision and severe deep burn" (ICSC (J) (2005)).
4 Respiratory sensitization Classification not possible - - - - No data available
4 Skin sensitization Category 1 Warning H317: May cause an allergic skin reaction P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P333+P313: If skin irritation or rash occurs: Get medical advice/attention.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P272: Contaminated work clothing should not be allowed out of the workplace.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P321: Specific treatment （see ... on this label）.
P363: Wash contaminated clothing before reuse.
P501: Dispose of contents/container to ... 		Based on the description in DFGOT vol.15 (2001) of the human health effects: "the substance induced skin sensitization." Also due to the fact that mercury is classified as "skin sensitization" by the ad hoc committee of the Japanese Society of Occupational Allergy, and "Skin Sensitizing Substance: Group 1" by the Japan Society for Occupational Health, though these classifications are not specifying mercury phenyl acetate per se.* * There is a provision to the effect that "the category refers to the substance concerned and its compounds, but does not identify all substances causing respiratory/skin sensitization.
5 Germ cell mutagenicity Category 2 Warning H341: Suspected of causing genetic defects P308+P313: IF exposed or concerned: Get medical advice/attention.
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P405: Store locked up.
P501: Dispose of contents/container to ... 		Based on positive data on somatic cell mutagenicity tests in vivo and the absence of data on germ cell genotoxicity in vivo. The positive results (as mercury compounds) are also available in multi-generation mutagenicity tests and germ cell mutagenicity tests in vivo, but not used for effects assessment.
6 Carcinogenicity Classification not possible - - - - Insufficient data available
7 Reproductive toxicity Category 2 Warning H361: Suspected of damaging fertility or the unborn child P308+P313: IF exposed or concerned: Get medical advice/attention.
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P405: Store locked up.
P501: Dispose of contents/container to ... 		Based on the evidence of central nervous/muscle system abnormality in offspring, described in RTECS (2006) (though no data are available on maternal toxicity).
8 Specific target organ toxicity - Single exposure Category 2 (kidney, respiratory system) Warning H371: May cause damage to organs (kidney, respiratory system) P309+P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P405: Store locked up.
P501: Dispose of contents/container to ... 		Based on the evidence reported in ICSC (J) 2000: "corrosive to the respiratory tract; corrosion following oral ingestion; adversely affects the kidney; may lead to renal failure. These effects may be delayed." Classified as priority 2 by ICSC (J).
9 Specific target organ toxicity - Repeated exposure Category 1 (nervous system, digestive system, respiratory system, kidney) Danger H372: Cause damage to organs through prolonged or repeated exposure (nervous system, digestive system, respiratory system, kidney) P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P314: Get medical advice/attention if you feel unwell.
P501: Dispose of contents/container to ... 		Based on the human evidence including "severe neurotoxicity...swelling of the mouth, reddening and malacia of the gingiva, coloring of gingiva (blue line), decayed tooth, buccopharyngeal swelling" and "dyspnea, respiratory depression, breathing disturbed by viscous liquid...purulent pneumonia noted at necropsy" following inhalation exposure (ATSDR (1999)), and the evidence from animal studies including "kidney damage" following oral exposure (IRIS (2002)). The effects on the mouth and gingiva observed in humans were not caused by direct irritation. The effects on experimental animals were observed at dosing levels within the guidance value ranges for Category 1.
10 Aspiration hazard Classification not possible - - - - No data available

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment （Acute） Classification not possible - - - - Classification not possible due to lack of data
11 Hazardous to the aquatic environment （Long-term） Classification not possible - - - - Classification not possible due to lack of data


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：
Reference Manual
Definitions / Abbreviations
Model Label by MHLW

 MHLW Website （in Japanese Only）
Model SDS by MHLW

 MHLW Website （in Japanese Only）

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